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Showing content from https://bioconductor.org/packages/devel/bioc/html/../../bioc/html/../../bioc/html/crupR.html below:

Bioconductor - crupR (development version)

crupR

This is the development version of crupR; for the stable release version, see crupR.

An R package to predict condition-specific enhancers from ChIP-seq data

Bioconductor version: Development (3.22)

An R package that offers a workflow to predict condition-specific enhancers from ChIP-seq data. The prediction of regulatory units is done in four main steps: Step 1 - the normalization of the ChIP-seq counts. Step 2 - the prediction of active enhancers binwise on the whole genome. Step 3 - the condition-specific clustering of the putative active enhancers. Step 4 - the detection of possible target genes of the condition-specific clusters using RNA-seq counts.

Author: Persia Akbari Omgba [cre], Verena Laupert [aut], Martin Vingron [aut]

Maintainer: Persia Akbari Omgba <omgba at molgen.mpg.de>

Citation (from within R, enter citation("crupR")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("crupR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("crupR")
Details biocViews DifferentialPeakCalling, FunctionalPrediction, GeneTarget, HistoneModification, PeakDetection, Software Version 1.1.0 In Bioconductor since BioC 3.21 (R-4.5) (< 6 months) License GPL-3 Depends R (>= 4.4.0) Imports bamsignals, Rsamtools, GenomicRanges, preprocessCore, randomForest, rtracklayer, GenomeInfoDb, S4Vectors, ggplot2, matrixStats, dplyr, IRanges, GenomicAlignments, GenomicFeatures, TxDb.Mmusculus.UCSC.mm10.knownGene, TxDb.Mmusculus.UCSC.mm9.knownGene, TxDb.Hsapiens.UCSC.hg19.knownGene, TxDb.Hsapiens.UCSC.hg38.knownGene, reshape2, magrittr, stats, utils, grDevices, SummarizedExperiment, BiocParallel, fs, methods System Requirements URL https://github.com/akbariomgba/crupR Bug Reports https://github.com/akbariomgba/crupR/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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