This is the development version of HiCDCPlus; for the stable release version, see HiCDCPlus.
Hi-C Direct Caller PlusBioconductor version: Development (3.22)
Systematic 3D interaction calls and differential analysis for Hi-C and HiChIP. The HiC-DC+ (Hi-C/HiChIP direct caller plus) package enables principled statistical analysis of Hi-C and HiChIP data sets â including calling significant interactions within a single experiment and performing differential analysis between conditions given replicate experiments â to facilitate global integrative studies. HiC-DC+ estimates significant interactions in a Hi-C or HiChIP experiment directly from the raw contact matrix for each chromosome up to a specified genomic distance, binned by uniform genomic intervals or restriction enzyme fragments, by training a background model to account for random polymer ligation and systematic sources of read count variation.
Author: Merve Sahin [cre, aut] ORCID: 0000-0003-3858-8332
Maintainer: Merve Sahin <merve.sahn at gmail.com>
Citation (from within R, entercitation("HiCDCPlus")): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("HiCDCPlus")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("HiCDCPlus")Follow Installation instructions to use this package in your R session.
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