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Takotsubo cardiomyopathy triggered by SARS-CoV-2 infection in a critically ill patient

Case Reports

. 2020 Jun 14;13(6):e236561. doi: 10.1136/bcr-2020-236561. Takotsubo cardiomyopathy triggered by SARS-CoV-2 infection in a critically ill patient

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Case Reports

Takotsubo cardiomyopathy triggered by SARS-CoV-2 infection in a critically ill patient

Fadi Taza et al. BMJ Case Rep. 2020.

. 2020 Jun 14;13(6):e236561. doi: 10.1136/bcr-2020-236561. Affiliations

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Abstract

COVID-19 became a global pandemic in early 2020. While well known for its pulmonary manifestations, the virus also has a number of cardiac manifestations as well. Takotsubo syndrome has scarcely been reported in patients with COVID-19, but it is possible that the cytokine storm associated with the infection can trigger Takotsubo syndrome in patients with underlying risk factors for Takotsubo (emotional distress, physical distress, history of psychiatric disorders).

Keywords: adult intensive care; cardiovascular medicine; heart failure; infectious diseases.

© BMJ Publishing Group Limited 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1

ECG with ST segment elevations…

Figure 1

ECG with ST segment elevations in leads II, III and aVF, suggesting inferior…

Figure 1

ECG with ST segment elevations in leads II, III and aVF, suggesting inferior wall myocardial infarction.

Figure 2

Coronary angiogram in left anterior…

Figure 2

Coronary angiogram in left anterior oblique view demonstrating patent right coronary artery.

Figure 2

Coronary angiogram in left anterior oblique view demonstrating patent right coronary artery.

Figure 3

Ventriculogram during left heart catheterisation…

Figure 3

Ventriculogram during left heart catheterisation with normal diastolic filling.

Figure 3

Ventriculogram during left heart catheterisation with normal diastolic filling.

Figure 4

Ventriculogram during left heart catheterisation…

Figure 4

Ventriculogram during left heart catheterisation showing apical ballooning consistent with Takotsubo syndrome.

Figure 4

Ventriculogram during left heart catheterisation showing apical ballooning consistent with Takotsubo syndrome.

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    1. Bybee KA, Kara T, Prasad A, et al. . Systematic review: transient left ventricular apical ballooning: a syndrome that mimics ST-segment elevation myocardial infarction. Ann Intern Med 2004;141:858. 10.7326/0003-4819-141-11-200412070-00010 - DOI - PubMed
    1. Templin C, Ghadri JR, Diekmann J, et al. . Clinical features and outcomes of takotsubo (stress) cardiomyopathy. N Engl J Med. - PubMed
    1. Cappelletti S, Ciallella C, Aromatario M, et al. . Takotsubo cardiomyopathy and sepsis. Angiology 2017;68:288–303. 10.1177/0003319716653886 - DOI - PubMed
    1. Gianni M, Dentali F, Grandi AM, et al. . Apical ballooning syndrome or takotsubo cardiomyopathy: a systematic review. Eur. Heart J 2006. - PubMed

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