Home - News ( United States | United Kingdom | Italy | Germany ) - Football scores

Showing content from http://www.ncbi.nlm.nih.gov/pubmed/32109013 below:

Clinical Characteristics of Coronavirus Disease 2019 in China

Collaborators, Affiliations

• China Medical Treatment Expert Group for Covid-19:

• ¹ From the State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University (W.G., W.L., J.H., R.C., C.T., T.W., S.L., Jin-lin Wang, N.Z., J.H., W.L.), the Departments of Thoracic Oncology (W.L.), Thoracic Surgery and Oncology (J.H.), and Emergency Medicine (Z.L.), First Affiliated Hospital of Guangzhou Medical University, and Guangzhou Eighth People's Hospital, Guangzhou Medical University (C.L.), and the State Key Laboratory of Organ Failure Research, Department of Biostatistics, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University (C.O., P.C.), Guangzhou, Wuhan Jinyintan Hospital (Z.N., J.X.), Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (Yu Hu), the Central Hospital of Wuhan (Y.P.), Wuhan No. 1 Hospital, Wuhan Hospital of Traditional Chinese and Western Medicine (L.W.), Wuhan Pulmonary Hospital (P.P.), Tianyou Hospital Affiliated to Wuhan University of Science and Technology (Jian-ming Wang), and the People's Hospital of Huangpi District (S.Z.), Wuhan, Shenzhen Third People's Hospital and the Second Affiliated Hospital of Southern University of Science and Technology, National Clinical Research Center for Infectious Diseases (L. Liu), and the Department of Clinical Microbiology and Infection Control, University of Hong Kong-Shenzhen Hospital (K.-Y.Y.), Shenzhen, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai (H.S.), the Department of Medicine and Therapeutics, Chinese University of Hong Kong, Shatin (D.S.C.H.), and the Department of Microbiology and the Carol Yu Center for Infection, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pok Fu Lam (K.-Y.Y.), Hong Kong, Medical ICU, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences (B.D.), and the Chinese Center for Disease Control and Prevention (G.Z.), Beijing, the State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou (L. Li), Chengdu Public Health Clinical Medical Center, Chengdu (Y.L.), Huangshi Central Hospital of Edong Healthcare Group, Affiliated Hospital of Hubei Polytechnic University, Huangshi (Ya-hua Hu), the First Hospital of Changsha, Changsha (J. Liu), the Third People's Hospital of Hainan Province, Sanya (Z.C.), Huanggang Central Hospital, Huanggang (G.L.), Wenling First People's Hospital, Wenling (Z.Z.), the Third People's Hospital of Yichang, Yichang (S.Q.), Affiliated Taihe Hospital of Hubei University of Medicine, Shiyan (J. Luo), and Xiantao First People's Hospital, Xiantao (C.Y.) - all in China.

• PMID: 32109013
• PMCID: PMC7092819
• DOI: 10.1056/NEJMoa2002032

Item in Clipboard

Wei-Jie Guan et al. N Engl J Med. 2020.

• China Medical Treatment Expert Group for Covid-19:

• ¹ From the State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University (W.G., W.L., J.H., R.C., C.T., T.W., S.L., Jin-lin Wang, N.Z., J.H., W.L.), the Departments of Thoracic Oncology (W.L.), Thoracic Surgery and Oncology (J.H.), and Emergency Medicine (Z.L.), First Affiliated Hospital of Guangzhou Medical University, and Guangzhou Eighth People's Hospital, Guangzhou Medical University (C.L.), and the State Key Laboratory of Organ Failure Research, Department of Biostatistics, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University (C.O., P.C.), Guangzhou, Wuhan Jinyintan Hospital (Z.N., J.X.), Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (Yu Hu), the Central Hospital of Wuhan (Y.P.), Wuhan No. 1 Hospital, Wuhan Hospital of Traditional Chinese and Western Medicine (L.W.), Wuhan Pulmonary Hospital (P.P.), Tianyou Hospital Affiliated to Wuhan University of Science and Technology (Jian-ming Wang), and the People's Hospital of Huangpi District (S.Z.), Wuhan, Shenzhen Third People's Hospital and the Second Affiliated Hospital of Southern University of Science and Technology, National Clinical Research Center for Infectious Diseases (L. Liu), and the Department of Clinical Microbiology and Infection Control, University of Hong Kong-Shenzhen Hospital (K.-Y.Y.), Shenzhen, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai (H.S.), the Department of Medicine and Therapeutics, Chinese University of Hong Kong, Shatin (D.S.C.H.), and the Department of Microbiology and the Carol Yu Center for Infection, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pok Fu Lam (K.-Y.Y.), Hong Kong, Medical ICU, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences (B.D.), and the Chinese Center for Disease Control and Prevention (G.Z.), Beijing, the State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou (L. Li), Chengdu Public Health Clinical Medical Center, Chengdu (Y.L.), Huangshi Central Hospital of Edong Healthcare Group, Affiliated Hospital of Hubei Polytechnic University, Huangshi (Ya-hua Hu), the First Hospital of Changsha, Changsha (J. Liu), the Third People's Hospital of Hainan Province, Sanya (Z.C.), Huanggang Central Hospital, Huanggang (G.L.), Wenling First People's Hospital, Wenling (Z.Z.), the Third People's Hospital of Yichang, Yichang (S.Q.), Affiliated Taihe Hospital of Hubei University of Medicine, Shiyan (J. Luo), and Xiantao First People's Hospital, Xiantao (C.Y.) - all in China.

• PMID: 32109013
• PMCID: PMC7092819
• DOI: 10.1056/NEJMoa2002032

Item in Clipboard

Background: Since December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, data have been needed on the clinical characteristics of the affected patients.

Methods: We extracted data regarding 1099 patients with laboratory-confirmed Covid-19 from 552 hospitals in 30 provinces, autonomous regions, and municipalities in mainland China through January 29, 2020. The primary composite end point was admission to an intensive care unit (ICU), the use of mechanical ventilation, or death.

Results: The median age of the patients was 47 years; 41.9% of the patients were female. The primary composite end point occurred in 67 patients (6.1%), including 5.0% who were admitted to the ICU, 2.3% who underwent invasive mechanical ventilation, and 1.4% who died. Only 1.9% of the patients had a history of direct contact with wildlife. Among nonresidents of Wuhan, 72.3% had contact with residents of Wuhan, including 31.3% who had visited the city. The most common symptoms were fever (43.8% on admission and 88.7% during hospitalization) and cough (67.8%). Diarrhea was uncommon (3.8%). The median incubation period was 4 days (interquartile range, 2 to 7). On admission, ground-glass opacity was the most common radiologic finding on chest computed tomography (CT) (56.4%). No radiographic or CT abnormality was found in 157 of 877 patients (17.9%) with nonsevere disease and in 5 of 173 patients (2.9%) with severe disease. Lymphocytopenia was present in 83.2% of the patients on admission.

Conclusions: During the first 2 months of the current outbreak, Covid-19 spread rapidly throughout China and caused varying degrees of illness. Patients often presented without fever, and many did not have abnormal radiologic findings. (Funded by the National Health Commission of China and others.).

Copyright © 2020 Massachusetts Medical Society.

PubMed Disclaimer

Shown are the official statistics…

Shown are the official statistics of all documented, laboratory-confirmed cases of coronavirus disease 2019 (Covid-19) throughout China, according to the National Health Commission as of February 4, 2020. The numerator denotes the number of patients who were included in the study cohort and the denominator denotes the number of laboratory-confirmed cases for each province, autonomous region, or provincial municipality, as reported by the National Health Commission.

• Clinical Characteristics of Covid-19 in China.

  Zavascki AP, Falci DR. Zavascki AP, et al. N Engl J Med. 2020 May 7;382(19):1859. doi: 10.1056/NEJMc2005203. Epub 2020 Mar 27. N Engl J Med. 2020. PMID: 32220202 No abstract available.

• Clinical Characteristics of Covid-19 in China.

  Chen ATC, Coura-Filho GB, Rehder MHH. Chen ATC, et al. N Engl J Med. 2020 May 7;382(19):1860. doi: 10.1056/NEJMc2005203. Epub 2020 Mar 27. N Engl J Med. 2020. PMID: 32220203 No abstract available.

• Clinical Characteristics of Covid-19 in China.

  Rolf JD. Rolf JD. N Engl J Med. 2020 May 7;382(19):1860. doi: 10.1056/NEJMc2005203. Epub 2020 Mar 27. N Engl J Med. 2020. PMID: 32220204 No abstract available.

• Clinical Characteristics of Covid-19 in China.

  Henry BM, Vikse J. Henry BM, et al. N Engl J Med. 2020 May 7;382(19):1860-1861. doi: 10.1056/NEJMc2005203. Epub 2020 Mar 27. N Engl J Med. 2020. PMID: 32220205 No abstract available.

• Importing coronavirus disease 2019 (COVID-19) into China after international air travel.

  Zhang XA, Fan H, Qi RZ, Zheng W, Zheng K, Gong JH, Fang LQ, Liu W. Zhang XA, et al. Travel Med Infect Dis. 2020 May-Jun;35:101620. doi: 10.1016/j.tmaid.2020.101620. Epub 2020 Mar 25. Travel Med Infect Dis. 2020. PMID: 32222421 Free PMC article. No abstract available.

• COVID-19, diabetes mellitus and ACE2: The conundrum.

  Pal R, Bhansali A. Pal R, et al. Diabetes Res Clin Pract. 2020 Apr;162:108132. doi: 10.1016/j.diabres.2020.108132. Epub 2020 Mar 29. Diabetes Res Clin Pract. 2020. PMID: 32234504 Free PMC article. No abstract available.

• Commentary: What is the relationship between Covid-19 and cardiovascular disease?

  Ferrari R, Di Pasquale G, Rapezzi C. Ferrari R, et al. Int J Cardiol. 2020 Jul 1;310:167-168. doi: 10.1016/j.ijcard.2020.03.074. Epub 2020 Mar 31. Int J Cardiol. 2020. PMID: 32276773 Free PMC article. No abstract available.

• Impact of COVID-19: perspectives from gastroenterology.

  Tay SW, Teh KKJ, Wang LM, Ang TL. Tay SW, et al. Singapore Med J. 2020 Sep;61(9):460-462. doi: 10.11622/smedj.2020051. Epub 2020 Apr 13. Singapore Med J. 2020. PMID: 32279480 Free PMC article. No abstract available.

• How we deal with the COVID-19 epidemic in an Italian paediatric onco-haematology clinic located in a region with a high density of cases.

  Sainati L, Biffi A. Sainati L, et al. Br J Haematol. 2020 May;189(4):640-642. doi: 10.1111/bjh.16699. Epub 2020 Apr 30. Br J Haematol. 2020. PMID: 32298461 Free PMC article. No abstract available.

• COVID-19: the risk of respiratory techniques in healthcare workers.

  Torres-Castro R, Vilaró J, Vera-Uribe R. Torres-Castro R, et al. Spinal Cord. 2020 Jun;58(6):724-725. doi: 10.1038/s41393-020-0472-0. Epub 2020 Apr 21. Spinal Cord. 2020. PMID: 32317765 Free PMC article. No abstract available.

• Rising Concern on Damaged Testis of COVID-19 Patients.

  Chen F, Lou D. Chen F, et al. Urology. 2020 Aug;142:42. doi: 10.1016/j.urology.2020.04.069. Epub 2020 Apr 25. Urology. 2020. PMID: 32343996 Free PMC article. No abstract available.

• Continuous positive airway pressure to avoid intubation in SARS-CoV-2 pneumonia: a two-period retrospective case-control study.

  Oranger M, Gonzalez-Bermejo J, Dacosta-Noble P, Llontop C, Guerder A, Trosini-Desert V, Faure M, Raux M, Decavele M, Demoule A, Morélot-Panzini C, Similowski T. Oranger M, et al. Eur Respir J. 2020 Aug 13;56(2):2001692. doi: 10.1183/13993003.01692-2020. Print 2020 Aug. Eur Respir J. 2020. PMID: 32430410 Free PMC article.

• A predictive model for disease progression in non-severely ill patients with coronavirus disease 2019.

  Ji M, Yuan L, Shen W, Lv J, Li Y, Chen J, Zhu C, Liu B, Liang Z, Lin Q, Xie W, Li M, Chen Z, Lu X, Ding Y, An P, Zhu S, Gao M, Ni H, Hu L, Shi G, Shi L, Dong W. Ji M, et al. Eur Respir J. 2020 Jul 16;56(1):2001234. doi: 10.1183/13993003.01234-2020. Print 2020 Jul. Eur Respir J. 2020. PMID: 32430433 Free PMC article.

• Smoking amidst the COVID-19 Pandemic - the invisible threat?

  Anand S. Anand S. Med J Malaysia. 2020 May;75(3):309-310. Med J Malaysia. 2020. PMID: 32467553

• Cholesterol: A new game player accelerating vasculopathy caused by SARS-CoV-2?

  Cao X, Yin R, Albrecht H, Fan D, Tan W. Cao X, et al. Am J Physiol Endocrinol Metab. 2020 Jul 1;319(1):E197-E202. doi: 10.1152/ajpendo.00255.2020. Epub 2020 Jun 5. Am J Physiol Endocrinol Metab. 2020. PMID: 32501731 Free PMC article.

• [Medical rehabilitation and COVID-19: Current impact and future challenges in rehabilitation services].

  Expósito Tirado JA, Rodríguez-Piñero Durán M, Echevarría Ruiz de Vargas C. Expósito Tirado JA, et al. Rehabilitacion (Madr). 2020 Oct-Dec;54(4):228-230. doi: 10.1016/j.rh.2020.06.002. Epub 2020 Jul 8. Rehabilitacion (Madr). 2020. PMID: 32723577 Free PMC article. Spanish. No abstract available.

• Maintaining Patient Safety and Data Integrity of Nonalcoholic Steatohepatitis Clinical Trials During the Severe Acute Respiratory Syndrome-Coronavirus 2 Pandemic.

  Alkhouri N, Kohli A, Loomba R, Harrison SA. Alkhouri N, et al. Hepatology. 2020 Nov;72(5):1509-1513. doi: 10.1002/hep.31522. Epub 2020 Oct 29. Hepatology. 2020. PMID: 32794597 Free PMC article. No abstract available.

• Collateral damage of the COVID-19 pandemic: Exacerbation of antimicrobial resistance and disruptions to antimicrobial stewardship programmes?

  Chibabhai V, Duse AG, Perovic O, Richards GA. Chibabhai V, et al. S Afr Med J. 2020 Jun 2;110(7):572-573. doi: 10.7196/SAMJ.2020.v110i7.14917. S Afr Med J. 2020. PMID: 32880323 No abstract available.

• Identification and validation of predictive factors for progression to severe COVID-19 pneumonia by proteomics.

  Di B, Jia H, Luo OJ, Lin F, Li K, Zhang Y, Wang H, Liang H, Fan J, Yang Z. Di B, et al. Signal Transduct Target Ther. 2020 Oct 3;5(1):217. doi: 10.1038/s41392-020-00333-1. Signal Transduct Target Ther. 2020. PMID: 33011738 Free PMC article. No abstract available.

• Thank You for Not Smoking.

  Hashmi SK, Hussain F, Hays JT. Hashmi SK, et al. Mayo Clin Proc. 2020 Oct;95(10):2062-2064. doi: 10.1016/j.mayocp.2020.08.012. Mayo Clin Proc. 2020. PMID: 33012336 Free PMC article. No abstract available.

• Tobacco and COVID-19: A position from Sociedade Portuguesa de Pneumologia.

  Matos CP, Boléo-Tomé JP, Rosa P, Morais A. Matos CP, et al. Pulmonology. 2021 Mar-Apr;27(2):91-93. doi: 10.1016/j.pulmoe.2020.11.002. Epub 2020 Nov 17. Pulmonology. 2021. PMID: 33303350 Free PMC article. No abstract available.

• COVID-19 Pandemic and the Burden of Acute Kidney Injury: The Known and the Unknown.

  Imam TH. Imam TH. Perm J. 2020 Dec;25:1. doi: 10.7812/TPP/20.140. Perm J. 2020. PMID: 33635771 Free PMC article.

• Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.

  Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, Zhao Y, Li Y, Wang X, Peng Z. Wang D, et al. JAMA. 2020 Mar 17;323(11):1061-1069. doi: 10.1001/jama.2020.1585. JAMA. 2020. PMID: 32031570 Free PMC article.

• Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2.

  Xu X, Yu C, Qu J, Zhang L, Jiang S, Huang D, Chen B, Zhang Z, Guan W, Ling Z, Jiang R, Hu T, Ding Y, Lin L, Gan Q, Luo L, Tang X, Liu J. Xu X, et al. Eur J Nucl Med Mol Imaging. 2020 May;47(5):1275-1280. doi: 10.1007/s00259-020-04735-9. Epub 2020 Feb 28. Eur J Nucl Med Mol Imaging. 2020. PMID: 32107577 Free PMC article.

• Epidemiological and clinical characteristics analysis of COVID-19 in the surrounding areas of Wuhan, Hubei Province in 2020.

  Zheng Y, Xiong C, Liu Y, Qian X, Tang Y, Liu L, Leung EL, Wang M. Zheng Y, et al. Pharmacol Res. 2020 Jul;157:104821. doi: 10.1016/j.phrs.2020.104821. Epub 2020 Apr 30. Pharmacol Res. 2020. PMID: 32360481 Free PMC article.

• Maternal and infant outcomes of full-term pregnancy combined with COVID-2019 in Wuhan, China: retrospective case series.

  Chen Y, Bai J. Chen Y, et al. Arch Gynecol Obstet. 2020 Sep;302(3):545-551. doi: 10.1007/s00404-020-05573-8. Epub 2020 Jul 21. Arch Gynecol Obstet. 2020. PMID: 32696241 Free PMC article. Review.

• Clinical Characteristics and Morbidity Associated With Coronavirus Disease 2019 in a Series of Patients in Metropolitan Detroit.

  Suleyman G, Fadel RA, Malette KM, Hammond C, Abdulla H, Entz A, Demertzis Z, Hanna Z, Failla A, Dagher C, Chaudhry Z, Vahia A, Abreu Lanfranco O, Ramesh M, Zervos MJ, Alangaden G, Miller J, Brar I. Suleyman G, et al. JAMA Netw Open. 2020 Jun 1;3(6):e2012270. doi: 10.1001/jamanetworkopen.2020.12270. JAMA Netw Open. 2020. PMID: 32543702 Free PMC article. Review.

• A rapid point-of-care population-scale dipstick assay to identify and differentiate SARS-CoV-2 variants in COVID-19-positive patients.

  Paul D, Verma J, Kumar S, Talukdar D, Jana P, Narendrakumar L, Kumar R, Tanwar S, Gosain M, Porey Karmakar S, Pareek M, Mani S, Chaudhuri S, Kshetrapal P, Wadhwa N, Bhatnagar S, Garg PK, Das B. Paul D, et al. Front Microbiol. 2024 Oct 21;15:1459644. doi: 10.3389/fmicb.2024.1459644. eCollection 2024. Front Microbiol. 2024. PMID: 39498137 Free PMC article.

• T-Cell Immune Responses to SARS-CoV-2 Infection and Vaccination.

  Notarbartolo S. Notarbartolo S. Vaccines (Basel). 2024 Sep 30;12(10):1126. doi: 10.3390/vaccines12101126. Vaccines (Basel). 2024. PMID: 39460293 Free PMC article. Review.

• COVID-19 and AKI: Where Do We Stand?

  Palevsky PM. Palevsky PM. J Am Soc Nephrol. 2021 May 3;32(5):1029-1032. doi: 10.1681/ASN.2020121768. Epub 2021 Feb 26. J Am Soc Nephrol. 2021. PMID: 33637516 Free PMC article. Review. No abstract available.

• Clinical, radiological and functional outcomes in patients with SARS-CoV-2 pneumonia: a prospective observational study.

  Gianella P, Rigamonti E, Marando M, Tamburello A, Grazioli Gauthier L, Argentieri G, Puligheddu C, Pagnamenta A, Pons M, Fusi-Schmidhauser T. Gianella P, et al. BMC Pulm Med. 2021 Apr 26;21(1):136. doi: 10.1186/s12890-021-01509-3. BMC Pulm Med. 2021. PMID: 33902513 Free PMC article.

• Virus-Induced Changes of the Respiratory Tract Environment Promote Secondary Infections With Streptococcus pneumoniae.

  Sender V, Hentrich K, Henriques-Normark B. Sender V, et al. Front Cell Infect Microbiol. 2021 Mar 22;11:643326. doi: 10.3389/fcimb.2021.643326. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 33828999 Free PMC article. Review.

1. 1. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020;395:497-506. - PMC - PubMed
2. 1. Lu R, Zhao X, Li J, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 2020;395:565-574. - PMC - PubMed
3. 1. Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 2020;382:727-733. - PMC - PubMed
4. 1. Chan JF, Yuan S, Kok KH, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet 2020;395:514-523. - PMC - PubMed
5. 1. Phan LT, Nguyen TV, Luong QC, et al. Importation and human-to-human transmission of a novel coronavirus in Vietnam. N Engl J Med. DOI: 10.1056/NEJMc2001272. - DOI - PMC - PubMed

RetroSearch is an open source project built by @garambo | Open a GitHub Issue

Search and Browse the WWW like it's 1997 | Search results from DuckDuckGo

HTML: 3.2 | Encoding: UTF-8 | Version: 0.7.3