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Showing content from http://www.ncbi.nlm.nih.gov/pubmed/28987544 below:

Adenoma detection rate influences the risk of metachronous advanced colorectal neoplasia in low-risk patients

Affiliations

• ¹ Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
• ² Statistics and Data Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

• PMID: 28987544
• DOI: 10.1016/j.gie.2017.09.028

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Tae Jun Kim et al. Gastrointest Endosc. 2018 Mar.

• ¹ Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
• ² Statistics and Data Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

• PMID: 28987544
• DOI: 10.1016/j.gie.2017.09.028

Item in Clipboard

Background and aims: In individuals with either no or 1 to 2 nonadvanced adenomas, future risks of advanced colorectal neoplasia (AN) vary according to clinical risk factors. However, little is known about the association between the adenoma detection rate (ADR) and the risk for metachronous AN in patients with low-risk adenomas.

Methods: We identified 7171 participants with no or 1 to 2 nonadvanced adenomas at first-time screening colonoscopy. The risk of metachronous AN was investigated at surveillance colonoscopy, according to clinical characteristics and the ADR.

Results: In multivariate analysis the risk for metachronous AN was strongly associated with increasing age, male sex, increasing number of adenomas, and the ADR of the endoscopist. With the ADR modeled as a continuous variable, each 1.0% increase in the rate of ADR predicted a 3.0% decrease in the risk of metachronous AN (adjusted odds ratio [OR], .97; 95% confidence interval [CI], .95-.99). With the ADR modeled using a binary cut-off (32%), the risk of metachronous AN was reduced in patients of endoscopists with an ADR ≥32% (adjusted OR, .53; 95% CI, .35-.83). Moreover, the risk of metachronous AN was reduced (adjusted OR, .66; 95% CI, .46-.95) in patients of endoscopists with an ADR in the highest tertile, compared with patients of endoscopists with ADRs in the lowest tertile. The impact of ADR on metachronous AN was significant for patients with low-risk adenomas rather than patients with no adenoma.

Conclusions: In patients with low-risk adenomas, the ADR of the endoscopist was inversely associated with the risk of metachronous AN.

Copyright © 2018 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

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• Dynamic adenoma detection rate influences the risk of metachronous advanced neoplasia after removal of low-risk findings in screening colonoscopy.

  Dong Z, Li O, Li Y, Xiao Z, Li F, Xu S, Ji D. Dong Z, et al. Surg Endosc. 2025 May;39(5):3354-3363. doi: 10.1007/s00464-025-11732-2. Epub 2025 Apr 17. Surg Endosc. 2025. PMID: 40246761 Free PMC article.

• Advanced adenoma detection rate is independent of nonadvanced adenoma detection rate.

  Greenspan M, Rajan KB, Baig A, Beck T, Mobarhan S, Melson J. Greenspan M, et al. Am J Gastroenterol. 2013 Aug;108(8):1286-92. doi: 10.1038/ajg.2013.149. Epub 2013 May 28. Am J Gastroenterol. 2013. PMID: 23711625

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  Kaminski MF, Wieszczy P, Rupinski M, Wojciechowska U, Didkowska J, Kraszewska E, Kobiela J, Franczyk R, Rupinska M, Kocot B, Chaber-Ciopinska A, Pachlewski J, Polkowski M, Regula J. Kaminski MF, et al. Gastroenterology. 2017 Jul;153(1):98-105. doi: 10.1053/j.gastro.2017.04.006. Epub 2017 Apr 17. Gastroenterology. 2017. PMID: 28428142

• A Review of the Management of Sporadic Colorectal Adenomas in Young People: Is Surveillance Wasted on the Young?

  Bushyhead D, Lin OST, Kozarek RA. Bushyhead D, et al. Dig Dis Sci. 2019 Aug;64(8):2107-2112. doi: 10.1007/s10620-019-05521-w. Epub 2019 Feb 20. Dig Dis Sci. 2019. PMID: 30788685 Review.

• Systematic review with meta-analysis: the incidence of advanced neoplasia after polypectomy in patients with and without low-risk adenomas.

  Hassan C, Gimeno-García A, Kalager M, Spada C, Zullo A, Costamagna G, Senore C, Rex DK, Quintero E. Hassan C, et al. Aliment Pharmacol Ther. 2014 May;39(9):905-12. doi: 10.1111/apt.12682. Epub 2014 Mar 4. Aliment Pharmacol Ther. 2014. PMID: 24593121 Review.

• Risk of Metachronous Advanced Neoplasia in Patients With Multiple Diminutive Adenomas.

  Kim JY, Kim TJ, Baek SY, Ahn S, Kim ER, Hong SN, Chang DK, Kim YH. Kim JY, et al. Am J Gastroenterol. 2018 Dec;113(12):1855-1861. doi: 10.1038/s41395-018-0210-9. Epub 2018 Aug 3. Am J Gastroenterol. 2018. PMID: 30072776 Free PMC article.

• Does Increased Adenoma Detection Reduce the Risk of Colorectal Cancer, and How Good Do We Need to Be?

  Dilly CK, Kahi CJ. Dilly CK, et al. Curr Gastroenterol Rep. 2019 Feb 28;21(4):9. doi: 10.1007/s11894-019-0678-5. Curr Gastroenterol Rep. 2019. PMID: 30815756 Review.

• Thinking Big About Small Adenomas: Moving Toward "Precision Surveillance".

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• Dynamic adenoma detection rate influences the risk of metachronous advanced neoplasia after removal of low-risk findings in screening colonoscopy.

  Dong Z, Li O, Li Y, Xiao Z, Li F, Xu S, Ji D. Dong Z, et al. Surg Endosc. 2025 May;39(5):3354-3363. doi: 10.1007/s00464-025-11732-2. Epub 2025 Apr 17. Surg Endosc. 2025. PMID: 40246761 Free PMC article.

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