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AMIGAS: a multicity, multicomponent cervical cancer prevention trial among Mexican American women

Randomized Controlled Trial

. 2013 Apr 1;119(7):1365-72. doi: 10.1002/cncr.27926. Epub 2012 Dec 21. AMIGAS: a multicity, multicomponent cervical cancer prevention trial among Mexican American women

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Randomized Controlled Trial

AMIGAS: a multicity, multicomponent cervical cancer prevention trial among Mexican American women

Theresa L Byrd et al. Cancer. 2013.

. 2013 Apr 1;119(7):1365-72. doi: 10.1002/cncr.27926. Epub 2012 Dec 21. Affiliation

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Abstract

Background: Considerable efforts have been undertaken in the United States to reduce cervical cancer incidence and mortality by increasing screening; however, disparities in screening rates continue to exist among certain racial and ethnic minority groups. The objective of the current study was to determine the effectiveness of a lay health worker-delivered intervention-AMIGAS (Ayudando a las Mujeres con Informacion, Guia, y Amor para su Salud [helping women with information, guidance, and love for their health])-to increase Papanicolaou (Pap) test screening among 3 populations of women of Mexican origin.

Methods: Six hundred thirteen women of Mexican origin in 3 treatment sites were randomized among 4 study arms: the full AMIGAS program with a video and a flip chart (n = 151), the AMIGAS program without the video (n = 154), the AMIGAS program without the flip chart (n = 155), and a usual care control group (n = 153). Six months after enrollment, women were surveyed and reported whether or not they had been screened.

Results: Women in any of the intervention arms were statistically significantly more likely to report being screened than those in the usual care group in both an intent-to-treat analysis and a per-protocol analysis. In the intent-to-treat analysis, 25% of women in the control group and 52% in the full AMIGAS program group reported having had Pap tests (P < .001); in the per-protocol analysis, the percentages were 29% and 62%, respectively (P < .001).

Conclusions: AMIGAS was effective in increasing Pap test screening among women of Mexican descent when used in a 1-to-1 setting. Future research should compare the 1-on-1 intervention with the group-based intervention.

Copyright © 2012 American Cancer Society.

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Conflict of interest statement

CONFLICT OF INTEREST DISCLOSURES

The authors made no disclosures.

Figures

Figure 1

The allocation of participants is…

Figure 1

The allocation of participants is illustrated for the study arms. Pap indicates Papanicolaou…

Figure 1

The allocation of participants is illustrated for the study arms. Pap indicates Papanicolaou test; ITT, intent-to-treat analysis; AMIGAS, Ayudando a las Mujeres con Informacion, Guia, y Amor para su Salud (helping women with information, guidance, and love for their health).

Similar articles Cited by References
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