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Impact of 3-tier formularies on drug treatment of attention-deficit/hyperactivity disorder in children

Comparative Study

doi: 10.1001/archpsyc.62.4.435. Impact of 3-tier formularies on drug treatment of attention-deficit/hyperactivity disorder in children

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Comparative Study

Impact of 3-tier formularies on drug treatment of attention-deficit/hyperactivity disorder in children

Haiden A Huskamp et al. Arch Gen Psychiatry. 2005 Apr.

doi: 10.1001/archpsyc.62.4.435. Affiliation

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Abstract

Background: Expenditures for medications used to treat attention-deficit/hyperactivity disorder (ADHD) in children have increased rapidly. Many employers and health plans have adopted 3-tier formularies in an attempt to control costs for these and other drugs.

Objective: To assess the effect of copayment increases associated with 3-tier formulary adoption on use and spending patterns for ADHD medications for children.

Design and setting: Observational study using quasi-experimental design to compare effects on ADHD medication use and spending for children enrolled as dependents in an employer-sponsored plan that made major changes to its pharmacy benefit design and a comparison group of children covered by the same insurer. The plan simultaneously moved from a 1-tier (same copayment required for all drugs) to a 3-tier formulary and implemented an across-the-board copayment increase. The plan later moved 3 drugs from tier 3 to tier 2.

Participants: An intervention group of 20 326 and a comparison group of 15 776 children aged 18 years and younger.

Main outcome measures: Monthly probability of using an ADHD medication; plan, enrollee, and total ADHD medication spending; and medication continuation.

Results: A 3-tier formulary implementation resulted in a 17% decrease in the monthly probability of using medication (P<.001), a 20% decrease in expected total medication expenditures, and a substantial shifting of costs from the plan to families (P<.001). Intervention group children using medications in the pre-period were more likely to change to a medication in a different tier after 3-tier adoption, relative to the comparison group (P = .08). The subsequent tier changes resulted in increased plan spending (P<.001) and decreased patient spending (P = .003) for users but no differences in continuation.

Conclusions: The copayment increases associated with 3-tier formulary implementation by 1 employer resulted in lower total ADHD medication spending, sizeable increases in out-of-pocket expenditures for families of children with ADHD, and a significant decrease in the probability of using these medications.

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Figures

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Monthly total spending on attention-deficit/hyperactivity disorder…

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Monthly total spending on attention-deficit/hyperactivity disorder medications for children aged 18 years and younger.

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Monthly total spending on attention-deficit/hyperactivity disorder medications for children aged 18 years and younger.

Similar articles Cited by References
    1. American Academy of Pediatrics. Clinical practice guideline: treatment of the school-aged child with attention-deficit/hyperactivity disorder. Pediatrics. 2001;108:1033–1044. - PubMed
    1. Biederman J. Practical considerations in stimulant drug selection for the attention-deficit/hyperactivity disorder patient–efficacy, potency and titration. Today’s Therapeutic Trends. 2002;20:311–328.
    1. Medco Health Solutions Inc. 2004 Drug Trend Report: Navigating the New Health Economy. Franklin Lakes, NJ: Medco Health Solutions Inc; 2004:5–27.
    1. Frank R. Prescription drug prices: why do some pay more than others do? Health Aff (Millwood) 2001;20:115–128. - PubMed
    1. Kaiser Family Foundation and the Health Research and Educational Trust. Employer Health Benefits 2004 Annual Report. Available at: http://www.kff.org/insurance/7148/index.cfm Accessed February 1, 2005.

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