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NCBI C++ ToolKit: src/objtools/edit/loc_edit.cpp Source File

76  else

best_id = sid.AsFastaString();

101

from = seq_int.

GetTo

();

104

f_from.

GetLabel

(&lab_from, from,

false

);

114

to = seq_int.

GetTo

();

118

f_from.

GetLabel

(&lab_from, from,

false

);

127  location

+= lab_from +

"-"

+ lab_to;

137  if

(seq_loc.

IsPnt

()) {

156  if

(seq_loc.

IsInt

()) {

161  const

list <CRef <CSeq_loc> >* seq_loc_ls;

162  if

(seq_loc.

IsMix

()) {

163

seq_loc_ls = &(seq_loc.

GetMix

().

Get

());

169  if

(it == seq_loc.

GetMix

().

Get

().begin()) {

199  else if

(seq_loc.

IsBond

()) {

278  size_t

num_intervals = last_l.

GetSize

();

279

last_l.

SetPos

(num_intervals - 1);

303  bool

& do_set_5_partial,

304  bool

& do_clear_5_partial)

const 306

do_set_5_partial =

false

;

307

do_clear_5_partial =

false

;

316

do_set_5_partial =

true

;

318  bool

confident =

false

;

320  if

(confident && !at_5) {

321

do_set_5_partial =

true

;

327  bool

confident =

false

;

329

do_set_5_partial =

true

;

337  bool

confident =

true

;

347

do_set_5_partial =

true

;

357

do_set_5_partial =

true

;

362

do_clear_5_partial =

true

;

367  bool

confident =

false

;

369

do_clear_5_partial =

true

;

380  bool

confident =

true

;

390

do_clear_5_partial =

true

;

395  return

do_set_5_partial || do_clear_5_partial;

402  bool

& do_set_3_partial,

403  bool

& do_clear_3_partial)

const 405

do_set_3_partial =

false

;

406

do_clear_3_partial =

false

;

415

do_set_3_partial =

true

;

417  bool

confident =

false

;

419  if

(confident && !at_3) {

420

do_set_3_partial =

true

;

426  bool

confident =

false

;

428  if

(at_3 && confident) {

429

do_set_3_partial =

true

;

437  bool

confident =

true

;

447

do_set_3_partial =

true

;

456

do_clear_3_partial =

true

;

461  bool

confident =

false

;

463  if

(!at_3 && confident) {

464

do_clear_3_partial =

true

;

472  bool

confident =

true

;

482

do_clear_3_partial =

true

;

487  return

do_set_3_partial || do_clear_3_partial;

520  size_t

num_intervals = last_l.

GetSize

();

521

last_l.

SetPos

(num_intervals - 1);

555  if

(pos < loc_start) {

557  id

->Assign(*(loc.

GetId

()));

559  new CSeq_loc

(*

id

,

static_cast<TSeqPos>

(pos), loc_start - 1, strand));

563

}

else if

(pos > loc_stop) {

565  id

->Assign(*(loc.

GetId

()));

567

*

id

, loc_stop + 1,

static_cast<TSeqPos>

(pos), strand));

584  bool

any_change =

false

;

587  bool

do_set_5_partial =

false

;

588  bool

do_clear_5_partial =

false

;

589

any_change |=

Interpret5Policy

(feat, scope, do_set_5_partial, do_clear_5_partial);

590  if

(do_set_5_partial) {

596

}

else if

(do_clear_5_partial) {

601  bool

do_set_3_partial =

false

;

602  bool

do_clear_3_partial =

false

;

603

any_change |=

Interpret3Policy

(feat, scope, do_set_3_partial, do_clear_3_partial);

604  if

(do_set_3_partial) {

610

}

else if

(do_clear_3_partial) {

619  bool

changed =

false

;

630  bool

changed =

false

;

661  if

((*it)->IsNull()) {

675

new_loc->

Assign

(orig_loc);

681  if

(subloc && !subloc->

IsNull

()) {

684

new_loc->

SetMix

().Set().push_back(add);

699

new_loc->

Assign

(orig_loc);

702  switch

(orig_loc.

Which

()) {

712

new_loc->

Assign

(orig_loc);

727

new_loc->

SetMix

().Set().push_back(null_loc);

730

new_loc->

SetMix

().Set().push_back(add);

754  switch

((orig_frame + diff % 3) % 3) {

765

feat.

SetData

().SetCdregion().SetFrame(new_frame);

772  bool

extend =

false

;

774  bool

confident =

false

;

807  bool

extend =

false

;

809  bool

confident =

false

;

812  size_t

num_intervals = last_l.

GetSize

();

813

last_l.

SetPos

(num_intervals - 1);

836  CScope

& scope,

bool

adjust_gene,

bool

retranslate_cds)

839

new_feat->

Assign

(orig_feat);

856

new_gene->

Assign

(*old_gene);

857  bool

gene_change =

false

;

915

interval.

SetTo

(from);

916

}

else if

(interval.

IsSetTo

()) {

977

vector<int> new_pnts;

982  ITERATE

(vector<int>, it, new_pnts) {

993  switch

(loc.

Which

()) {

1052  if

((*it)->IsSetLoc()) {

1126  switch

(loc.

Which

()) {

1129

CSeq_loc::TEquiv::Tdata::iterator it = loc.

SetEquiv

().Set().begin();

1130  while

(it != loc.

SetEquiv

().Set().end()) {

1133

it = loc.

SetEquiv

().Set().erase(it);

1144

}

else if

(loc.

GetEquiv

().

Get

().size() == 0) {

1152

CSeq_loc::TMix::Tdata::iterator it = loc.

SetMix

().Set().begin();

1153  while

(it != loc.

SetMix

().Set().end()) {

1156

it = loc.

SetMix

().Set().erase(it);

1163  if

(loc.

GetMix

().

Get

().size() == 1) {

1167

}

else if

(loc.

GetMix

().

Get

().size() == 0) {

1179

loc.

SetInt

().Assign(*sub);

1197

loc.

SetPnt

().Assign(*sub);

1210  bool

& bCompleteCut,

1229  TSeqPos

cut_size = cut_to - cut_from + 1;

1232  if

(feat_to < cut_from)

1239  if

(feat_from >= cut_from && feat_to <= cut_to)

1242

bCompleteCut =

true

;

1243

trim5 += feat_from - feat_to + 1;

1248  if

(feat_from > cut_to)

1251

feat_from -= cut_size;

1252

feat_to -= cut_size;

1253

interval.

SetFrom

(feat_from);

1254

interval.

SetTo

(feat_to);

1269  if

(feat_to > cut_to) {

1271

feat_to -= cut_size;

1276  TSeqPos

diff = cut_from - 1 - feat_to;

1279

feat_to = cut_from - 1;

1283  if

(feat_from >= cut_from) {

1285  TSeqPos

diff = cut_to + 1 - feat_from;

1288

feat_from = cut_to + 1;

1289

feat_from -= cut_size;

1292

interval.

SetFrom

(feat_from);

1293

interval.

SetTo

(feat_to);

1301  bool

& bCompleteCut,

1305  if

(packint.

IsSet

()) {

1308

CPacked_seqint::Tdata::iterator it;

1309  for

(it = packint.

Set

().begin();

1310

it != packint.

Set

().end(); )

1312  bool

bDeleted =

false

;

1315

bDeleted, this_trim, bAdjusted);

1322

it = packint.

Set

().erase(it);

1329  if

(packint.

Get

().empty()) {

1333  if

(!packint.

IsSet

()) {

1334

bCompleteCut =

true

;

1342  bool

& bCompleteCut,

1346  if

(mix.

IsSet

()) {

1349

CSeq_loc_mix::Tdata::iterator it;

1350  for

(it = mix.

Set

().begin();

1351

it != mix.

Set

().end(); )

1353  bool

bDeleted =

false

;

1362

it = mix.

Set

().erase(it);

1370  if

(!mix.

IsSet

() || mix.

Set

().empty()) {

1371

bCompleteCut =

true

;

1379  bool

& bCompleteCut,

1388  auto

diff = to - from + 1;

1391

}

else if

(from < pnt.

GetPoint

()) {

1392

bCompleteCut =

true

;

1401  bool

& bCompleteCut,

TSeqPos

& trim5,

bool

& bAdjusted)

1407  if

(

pack

.IsSetPoints()) {

1409  auto

it =

pack

.SetPoints().begin();

1410  while

(it !=

pack

.SetPoints().end()) {

1412  auto

diff = to - from + 1;

1417

}

else if

(from < *it) {

1418

it =

pack

.SetPoints().erase(it);

1429  if

(

pack

.SetPoints().empty()) {

1430

bCompleteCut =

true

;

1438  bool

& bCompleteCut,

1442  bool

cutA =

false

, cutB =

false

;

1455

bCompleteCut =

true

;

1463  bool

& bCompleteCut,

1468

CSeq_loc_equiv::Tdata::iterator it = equiv.

Set

().begin();

1469  while

(it != equiv.

Set

().end()) {

1473  if

(this_trim5 > max_trim5) {

1474

max_trim5 = this_trim5;

1477

it = equiv.

Set

().erase(it);

1482  if

(equiv.

Set

().empty()) {

1483

bCompleteCut =

true

;

1492  bool

& bCompleteCut,

1493  TSeqPos

& trim5,

bool

& bAdjusted)

1497  switch

(loc.

Which

())

1502

bCompleteCut, trim5, bAdjusted);

1534  if

(!bCompleteCut) {

1559  TSeqPos

insert_size = insert_to - insert_from + 1;

1562  if

(feat_to < insert_from)

1569  if

(feat_from > insert_from) {

1570

feat_from += insert_size;

1571

feat_to += insert_size;

1572

interval.

SetFrom

(feat_from);

1573

interval.

SetTo

(feat_to);

1578  if

(feat_from <= insert_from && feat_to >= insert_from)

1580

feat_to += insert_size;

1581

interval.

SetTo

(feat_to);

1591  if

(packint.

IsSet

()) {

1593

CPacked_seqint::Tdata::iterator it;

1594  for

(it = packint.

Set

().begin();

1595

it != packint.

Set

().end(); it++)

1607  if

(mix.

IsSet

()) {

1609

CSeq_loc_mix::Tdata::iterator it;

1610  for

(it = mix.

Set

().begin();

1611

it != mix.

Set

().end(); it++)

1630  if

(insert_from < pnt.

GetPoint

()) {

1631  auto

diff = insert_to - insert_from + 1;

1645  auto

it = packpnt.

SetPoints

().begin();

1646  while

(it != packpnt.

SetPoints

().end()) {

1648  auto

diff = to - from + 1;

1674

CSeq_loc_equiv::Tdata::iterator it = equiv.

Set

().begin();

1675  while

(it != equiv.

Set

().end()) {

1688  switch

(loc.

Which

())

1730  const CSeq_id

* seqid,

bool

& cut,

1731  unsigned int

options)

1747  if

(feat_to < start) {

1758  if

(feat_from < start && feat_to > stop) {

1765  if

(feat_to > stop) {

1768  if

(stop + 1 > feat_from) {

1775  if

(feat_from < start) {

1776

before.

SetTo

(start - 1);

1790  const CSeq_id

* seqid,

unsigned int

options)

1792  if

(before_intervals.

IsSet

()) {

1794

reverse(before_intervals.

Set

().begin(), before_intervals.

Set

().end());

1797  auto

it = before_intervals.

Set

().begin();

1798  while

(it != before_intervals.

Set

().end()) {

1802  if

(int_from > stop && after_intervals.

IsSet

() && !after_intervals.

Get

().empty()) {

1803

after_intervals.

Set

().push_back(

Ref

(&sub_interval));

1804

it = before_intervals.

Set

().erase(it);

1812

it = before_intervals.

Set

().erase(it);

1818

after_intervals.

Set

().push_back(after);

1824

reverse(after_intervals.

Set

().begin(), after_intervals.

Set

().end());

1827

reverse(before_intervals.

Set

().begin(), before_intervals.

Set

().end());

1834  size_t

start,

size_t

stop,

1835  const CSeq_id

* seqid,

unsigned int

options)

1840  switch

(loc1.

Which

())

1848

seqid, cut, options);

1886  if

(before_intervals.

Set

().empty()) {

1889  if

(!after_intervals->Set().empty()) {

1906  if

(before_mix.

IsSet

()) {

1908

reverse(before_mix.

Set

().begin(), before_mix.

Set

().end());

1910  auto

it = before_mix.

Set

().begin();

1911  while

(it != before_mix.

Set

().end()) {

1915  if

(from > stop && after_mix->IsSet() && !after_mix->Get().empty()) {

1916

after_mix->Set().push_back(

Ref

(&sub_loc));

1917

it = before_mix.

Set

().erase(it);

1924

it = before_mix.

Set

().erase(it);

1930

after_mix->Set().push_back(after);

1935  if

(after_mix->IsReverseStrand()) {

1936

reverse(after_mix->Set().begin(), after_mix->Set().end());

1939

reverse(before_mix.

Set

().begin(), before_mix.

Set

().end());

1943  if

(before_mix.

Set

().empty()) {

1946  if

(!after_mix->Set().empty()) {

1948

loc2.

SetMix

().Assign(*after_mix);

1952

add->

SetMix

().Assign(*after_mix);

1963  if

(before_equiv.

IsSet

()) {

1965

CSeq_loc_equiv::Tdata::iterator it;

1966  for

(it = before_equiv.

Set

().begin();

1967

it != before_equiv.

Set

().end(); )

1973

it = before_equiv.

Set

().erase(it);

1979

after_equiv->Set().push_back(after);

1984  if

(before_equiv.

Set

().empty()) {

1987  if

(!after_equiv->Set().empty()) {

1989

loc2.

SetMix

().Assign(*after_equiv);

1992

add->

SetMix

().Assign(*after_equiv);

2003

CPacked_seqpnt::TPoints::iterator it = loc1.

SetPacked_pnt

().SetPoints().begin();

2006

after_points.push_back(*it);

2009

it = before_points.erase(it);

2014  if

(!after_points.empty()) {

2017

after->SetPoints().assign(after_points.begin(), after_points.end());

2026  if

(before_points.empty()) {

2049

CCdregion::TCode_break::iterator it = cdr.

SetCode_break

().begin();

2051  if

((*it)->IsSetLoc()) {

2053  bool

adjusted =

false

;

2077  bool

trimmed =

false

;

2090  bool

& bCompleteCut,

2118

CCdregion::TCode_break::iterator it = cdr.

SetCode_break

().begin();

2120  if

((*it)->IsSetLoc()) {

2212  if

(pint.

Get

().size() < 2) {

2215  bool

any_change =

false

;

2217  bool

this_change =

true

;

2218  while

(this_change) {

2219

this_change =

false

;

2222

CPacked_seqint::Tdata::iterator

a

= pint.

Set

().begin();

2223

CPacked_seqint::Tdata::iterator

b

=

a

;

2225  while

(

b

!= pint.

Set

().end()) {

2226  if

((*a)->IsSetId() && (*b)->IsSetId() &&

2227

(*a)->GetId().Equals((*b)->GetId()) &&

2228

(*a)->IsSetFrom() && (*a)->IsSetTo() && (*a)->GetFrom() < (*a)->GetTo() &&

2229

(*b)->IsSetFrom() && (*b)->IsSetTo() && (*b)->GetFrom() < (*b)->GetTo() &&

2232  if

((*b)->GetTo() > (*a)->GetFrom()) {

2234  a

->Reset(

b

->GetPointer());

2236

this_change =

true

;

2240  if

((*b)->GetTo() < (*a)->GetFrom()) {

2242  a

->Reset(

b

->GetPointer());

2244

this_change =

true

;

2278  if

(this_strand != strand) {

2292  bool

any_change =

false

;

2296  if

(mix.size() < 2) {

2299  bool

this_change =

true

;

2300  while

(this_change) {

2301

this_change =

false

;

2304

CSeq_loc::TMix::Tdata::iterator

a

= mix.begin();

2305

CSeq_loc::TMix::Tdata::iterator

b

=

a

;

2307  while

(

b

!= mix.end()) {

2316

a_strand == b_strand) {

2320  a

->Reset(

b

->GetPointer());

2322

this_change =

true

;

2328  a

->Reset(

b

->GetPointer());

2330

this_change =

true

;

2348  bool

any_change =

false

;

2349  switch

(loc.

Which

()) {

2388  if

((*it)->IsLiteral()) {

2389  offset

+= (*it)->GetLiteral().GetLength();

2390  if

(!(*it)->GetLiteral().IsSetSeq_data()) {

2392

}

else if

((*it)->GetLiteral().GetSeq_data().IsGap()) {

2395

}

else if

((*it)->IsLoc()) {

2402  if

(left >= last_gap_stop && left - last_gap_stop <= 3) {

2404

extend_len = left - last_gap_stop;

2416

extend_len = seq.

GetLength

() - right - 1;

2424  if

((*it)->IsLiteral()) {

2425  if

(!(*it)->GetLiteral().IsSetSeq_data()) {

2426

next_gap_start =

offset

;

2427

}

else if

((*it)->GetLiteral().GetSeq_data().IsGap()) {

2428

next_gap_start =

offset

;

2430  offset

+= (*it)->GetLiteral().GetLength();

2431

}

else if

((*it)->IsLoc()) {

2434  if

(

offset

> right + 4) {

2438  if

(next_gap_start > right && next_gap_start - right - 1 <= 3) {

2440

extend_len = next_gap_start - right - 1;

2462  bool

extendable =

false

;

2468

new_start = start - extend_len;

2471  if

(start < seq->GetInst().

GetLength

() - 1) {

2473

new_start = start + extend_len;

2479  for

(

auto

it : related_features) {

2483

it->SetLocation().Assign(*related_loc);

2484  if

(it->IsSetData() && it->GetData().IsCdregion()) {

2512  size_t

num_intervals = last_l.

GetSize

();

2513

last_l.

SetPos

(num_intervals - 1);

2521  bool

extendable =

false

;

2525  if

(stop < seq->GetInst().

GetLength

() - 1) {

2527

new_stop = stop + extend_len;

2532

new_stop = stop - extend_len;

2538  for

(

auto

it : related_features) {

2542

it->SetLocation().Assign(*related_loc);

2563  if

(

IsExtendableLeft

(start, *seq, &scope, extend_len) && extend_len > 0) {

2569  size_t

num_intervals = last_l.

GetSize

();

2570

last_l.

SetPos

(num_intervals - 1);

2587  bool

any_change =

false

;

2591  if

(

f

->GetData().IsCdregion()) {

2594

vector<CRef<CSeq_feat> > related_features;

2598

related_features.push_back(new_gene);

2603

related_features.push_back(new_mRNA);

2606

new_cds->

Assign

(*(

f

->GetOriginalSeq_feat()));

2611  if

(adjusted_5prime || adjusted_3prime) {

2617

geh.

Replace

(*(related_features.front()));

2621

meh.

Replace

(*(related_features.back()));

User-defined methods of the data storage class.

User-defined methods of the data storage class.

User-defined methods of the data storage class.

User-defined methods of the data storage class.

@ eExtreme_Positional

numerical value

@ eExtreme_Biological

5' and 3'

User-defined methods of the data storage class.

User-defined methods of the data storage class.

User-defined methods of the data storage class.

TSeqPos GetLength(void) const

void GetLabel(string *label, TSeqPos pos, bool right=true) const

static CRef< CSeq_loc > ConvertToOrder(const CSeq_loc &orig_loc, bool &changed)

bool Interpret5Policy(const CSeq_feat &orig_feat, CScope &scope, bool &do_set_5_partial, bool &do_clear_5_partial) const

@ eMergePolicy_SingleInterval

static bool HasNulls(const CSeq_loc &orig_loc)

static bool Extend3(CSeq_feat &feat, CScope &scope)

static bool Extend5(CSeq_feat &feat, CScope &scope)

static CRef< CSeq_loc > ConvertToJoin(const CSeq_loc &orig_loc, bool &changed)

EPartialPolicy m_PartialPolicy3

static bool Is3AtEndOfSeq(const CSeq_loc &loc, CBioseq_Handle bsh)

static bool Is5AtEndOfSeq(const CSeq_loc &loc, CBioseq_Handle bsh)

EPartialPolicy m_PartialPolicy5

@ ePartialPolicy_eSetForFrame

@ ePartialPolicy_eSetAtEnd

@ ePartialPolicy_eNoChange

@ ePartialPolicy_eSetForBadEnd

@ ePartialPolicy_eClearForGoodEnd

@ ePartialPolicy_eClearNotAtEnd

EMergePolicy m_MergePolicy

bool Interpret3Policy(const CSeq_feat &orig_feat, CScope &scope, bool &do_set_3_partial, bool &do_clear_3_partial) const

bool ApplyPolicyToFeature(CSeq_feat &feat, CScope &scope) const

bool IsReverseStrand(void) const

ESubtype GetSubtype(void) const

CSeq_feat_EditHandle –.

namespace ncbi::objects::

Seq-loc iterator class – iterates all intervals from a seq-loc in the correct order.

bool IsReverseStrand(void) const

Include a standard set of the NCBI C++ Toolkit most basic headers.

static DLIST_TYPE *DLIST_NAME() first(DLIST_LIST_TYPE *list)

static const char * pack(const char *fmt,...)

static const char location[]

unsigned int TSeqPos

Type for sequence locations and lengths.

#define ITERATE(Type, Var, Cont)

ITERATE macro to sequence through container elements.

#define NON_CONST_ITERATE(Type, Var, Cont)

Non constant version of ITERATE macro.

void swap(NCBI_NS_NCBI::pair_base_member< T1, T2 > &pair1, NCBI_NS_NCBI::pair_base_member< T1, T2 > &pair2)

virtual void Assign(const CSerialObject &source, ESerialRecursionMode how=eRecursive)

Set object to copy of another one.

virtual bool Equals(const CSerialObject &object, ESerialRecursionMode how=eRecursive) const

Check if both objects contain the same values.

const string AsFastaString(void) const

CConstRef< CSeq_id > GetSeqId(void) const

E_SIC Compare(const CSeq_id &sid2) const

Compare() - more general.

@ e_YES

SeqIds compared, but are different.

void SetPacked_int(TPacked_int &v)

void InvalidateCache(void) const

Combine invalidation of all cached values.

void SetPacked_pnt(TPacked_pnt &v)

bool IsPartialStart(ESeqLocExtremes ext) const

check start or stop of location for e_Lim fuzz

ENa_strand GetStrand(void) const

Get the location's strand.

virtual void Assign(const CSerialObject &source, ESerialRecursionMode how=eRecursive)

Override Assign() to incorporate cache invalidation.

TSeqPos GetStart(ESeqLocExtremes ext) const

Return start and stop positions of the seq-loc.

CConstRef< CSeq_loc > GetRangeAsSeq_loc(void) const

Get seq-loc for the current iterator position.

bool IsSetStrand(void) const

Get strand.

void Add(const CSeq_loc &other)

Simple adding of seq-locs.

bool IsSetStrand(EIsSetStrand flag=eIsSetStrand_Any) const

Check if strand is set for any/all part(s) of the seq-loc depending on the flag.

void SetPos(size_t pos)

Set iterator's position.

const CSeq_id * GetId(void) const

Get the id of the location return NULL if has multiple ids or no id at all.

size_t GetSize(void) const

Get number of ranges.

TRange GetRange(void) const

Get the range.

void SetPartialStart(bool val, ESeqLocExtremes ext)

set / remove e_Lim fuzz on start or stop (lt/gt - indicating partial interval)

ENa_strand GetStrand(void) const

const CSeq_id & GetSeq_id(void) const

Get seq_id of the current location.

void GetLabel(string *label) const

Appends a label suitable for display (e.g., error messages) label must point to an existing string ob...

void SetPartialStop(bool val, ESeqLocExtremes ext)

void SetNull(void)

Override all setters to incorporate cache invalidation.

bool IsPartialStop(ESeqLocExtremes ext) const

TSeqPos GetStop(ESeqLocExtremes ext) const

bool RetranslateCDS(const CSeq_feat &cds, CScope &scope)

RetranslateCDS A function to replace the protein Bioseq pointed to by cds.product with the current tr...

bool AdjustFeaturePartialFlagForLocation(CSeq_feat &new_feat)

AdjustFeaturePartialFlagForLocation A function to ensure that Seq-feat.partial is set if either end o...

bool AdjustForCDSPartials(const CSeq_feat &cds, CSeq_entry_Handle seh)

AdjustForCDSPartials A function to make all of the necessary related changes to a Seq-entry after the...

const CSeq_id & GetId(const CSeq_loc &loc, CScope *scope)

If all CSeq_ids embedded in CSeq_loc refer to the same CBioseq, returns the first CSeq_id found,...

TSeqPos GetLength(const CSeq_id &id, CScope *scope)

Get sequence length if scope not null, else return max possible TSeqPos.

sequence::ECompare Compare(const CSeq_loc &loc1, const CSeq_loc &loc2, CScope *scope)

Returns the sequence::ECompare containment relationship between CSeq_locs.

CRef< CSeq_loc > Seq_loc_Merge(const CSeq_loc &loc, CSeq_loc::TOpFlags flags, CScope *scope)

Merge ranges in the seq-loc.

CRef< CSeq_loc > Seq_loc_Add(const CSeq_loc &loc1, const CSeq_loc &loc2, CSeq_loc::TOpFlags flags, CScope *scope)

Add two seq-locs.

@ fCompareOverlapping

Check if seq-locs are overlapping.

@ eSame

CSeq_locs contain each other.

CConstRef< CSeq_feat > GetOverlappingGene(const CSeq_loc &loc, CScope &scope, ETransSplicing eTransSplicing=eTransSplicing_Auto)

static void Translate(const string &seq, string &prot, const CGenetic_code *code, bool include_stop=true, bool remove_trailing_X=false, bool *alt_start=NULL, bool is_5prime_complete=true, bool is_3prime_complete=true)

Translate a string using a specified genetic code.

@ eGetId_Best

return the "best" gi (uses FindBestScore(), with CSeq_id::CalculateScore() as the score function

CBioseq_Handle GetBioseqHandle(const CSeq_id &id)

Get bioseq handle by seq-id.

CSeq_feat_Handle GetSeq_featHandle(const CSeq_feat &feat, EMissing action=eMissing_Default)

CConstRef< CBioseq > GetCompleteBioseq(void) const

Get the complete bioseq.

const CSeq_annot_Handle & GetAnnot(void) const

Get handle to seq-annot for this feature.

TSeqPos GetBioseqLength(void) const

CSeq_entry_Handle GetParentEntry(void) const

Get parent Seq-entry handle.

CSeq_entry_EditHandle GetEditHandle(void) const

Get 'edit' version of handle.

TInst_Length GetInst_Length(void) const

CScope & GetScope(void) const

Get scope this handle belongs to.

CConstRef< CSeq_feat > GetOriginalSeq_feat(void) const

void Replace(const CSeq_feat &new_feat) const

Replace the feature with new Seq-feat object.

const TInst & GetInst(void) const

CRef< C > Ref(C *object)

Helper functions to get CRef<> and CConstRef<> objects.

TObjectType * GetPointer(void) THROWS_NONE

Get pointer,.

void Reset(void)

Reset reference object.

#define END_NCBI_SCOPE

End previously defined NCBI scope.

#define END_SCOPE(ns)

End the previously defined scope.

#define BEGIN_NCBI_SCOPE

Define ncbi namespace.

#define BEGIN_SCOPE(ns)

Define a new scope.

static bool EndsWith(const CTempString str, const CTempString end, ECase use_case=eCase)

Check if a string ends with a specified suffix value.

static string IntToString(int value, TNumToStringFlags flags=0, int base=10)

Convert int to string.

static bool StartsWith(const CTempString str, const CTempString start, ECase use_case=eCase)

Check if a string starts with a specified prefix value.

@ eNocase

Case insensitive compare.

TTo GetTo(void) const

Get the To member data.

TFrom GetFrom(void) const

Get the From member data.

bool IsSetAnticodon(void) const

location of anticodon Check if a value has been assigned to Anticodon data member.

void SetAnticodon(TAnticodon &value)

Assign a value to Anticodon data member.

void ResetAnticodon(void)

Reset Anticodon data member.

bool IsSetData(void) const

the specific data Check if a value has been assigned to Data data member.

void SetLocation(TLocation &value)

Assign a value to Location data member.

bool IsCdregion(void) const

Check if variant Cdregion is selected.

void ResetCode_break(void)

Reset Code_break data member.

const TLocation & GetLocation(void) const

Get the Location member data.

list< CRef< CCode_break > > TCode_break

TFrame GetFrame(void) const

Get the Frame member data.

const TData & GetData(void) const

Get the Data member data.

void SetData(TData &value)

Assign a value to Data data member.

TCode_break & SetCode_break(void)

Assign a value to Code_break data member.

const TCdregion & GetCdregion(void) const

Get the variant data.

const TCode_break & GetCode_break(void) const

Get the Code_break member data.

bool IsSetProduct(void) const

product of process Check if a value has been assigned to Product data member.

bool IsSetCode_break(void) const

individual exceptions Check if a value has been assigned to Code_break data member.

bool IsSetFrame(void) const

Check if a value has been assigned to Frame data member.

bool IsSetLocation(void) const

feature made from Check if a value has been assigned to Location data member.

@ eFrame_not_set

not set, code uses one

@ eFrame_three

reading frame

bool IsSet(void) const

Check if a value has been assigned to data member.

void SetTo(TTo value)

Assign a value to To data member.

const TFuzz_from & GetFuzz_from(void) const

Get the Fuzz_from member data.

void SetPoint(TPoint value)

Assign a value to Point data member.

void SetId(TId &value)

Assign a value to Id data member.

void SetA(TA &value)

Assign a value to A data member.

bool IsSetId(void) const

WARNING: this used to be optional Check if a value has been assigned to Id data member.

void ResetFuzz_to(void)

Reset Fuzz_to data member.

bool IsMix(void) const

Check if variant Mix is selected.

bool CanGetFuzz_to(void) const

Check if it is safe to call GetFuzz_to method.

const TB & GetB(void) const

Get the B member data.

list< CRef< CSeq_interval > > Tdata

ENa_strand

strand of nucleic acid

const Tdata & Get(void) const

Get the member data.

bool CanGetStrand(void) const

Check if it is safe to call GetStrand method.

void ResetPoints(void)

Reset Points data member.

TStrand GetStrand(void) const

Get the Strand member data.

const TId & GetId(void) const

Get the Id member data.

bool IsSetPoint(void) const

Check if a value has been assigned to Point data member.

bool IsSetPoints(void) const

Check if a value has been assigned to Points data member.

bool IsPacked_pnt(void) const

Check if variant Packed_pnt is selected.

Tdata & Set(void)

Assign a value to data member.

const TPnt & GetPnt(void) const

Get the variant data.

TPoint GetPoint(void) const

Get the Point member data.

const TFuzz_to & GetFuzz_to(void) const

Get the Fuzz_to member data.

bool IsSetA(void) const

connection to a least one residue Check if a value has been assigned to A data member.

void SetStrand(TStrand value)

Assign a value to Strand data member.

bool IsSetStrand(void) const

Check if a value has been assigned to Strand data member.

TFrom GetFrom(void) const

Get the From member data.

bool CanGetTo(void) const

Check if it is safe to call GetTo method.

void SetFuzz(TFuzz &value)

Assign a value to Fuzz data member.

bool IsSetFuzz(void) const

Check if a value has been assigned to Fuzz data member.

list< CRef< CSeq_loc > > Tdata

bool IsEquiv(void) const

Check if variant Equiv is selected.

E_Choice Which(void) const

Which variant is currently selected.

const TId & GetId(void) const

Get the Id member data.

const TId & GetId(void) const

Get the Id member data.

bool IsSet(void) const

Check if a value has been assigned to data member.

void SetFrom(TFrom value)

Assign a value to From data member.

bool IsBond(void) const

Check if variant Bond is selected.

bool IsSetFuzz(void) const

Check if a value has been assigned to Fuzz data member.

const Tdata & Get(void) const

Get the member data.

const TPacked_pnt & GetPacked_pnt(void) const

Get the variant data.

void SetFuzz(TFuzz &value)

Assign a value to Fuzz data member.

const Tdata & Get(void) const

Get the member data.

void ResetFuzz_from(void)

Reset Fuzz_from data member.

const TEquiv & GetEquiv(void) const

Get the variant data.

TPoints & SetPoints(void)

Assign a value to Points data member.

list< CRef< CSeq_loc > > Tdata

vector< TSeqPos > TPoints

virtual void Reset(void)

Reset the whole object.

void SetFuzz_to(TFuzz_to &value)

Assign a value to Fuzz_to data member.

void SetFuzz_from(TFuzz_from &value)

Assign a value to Fuzz_from data member.

bool IsPacked_int(void) const

Check if variant Packed_int is selected.

const TA & GetA(void) const

Get the A member data.

bool IsSetTo(void) const

Check if a value has been assigned to To data member.

bool IsSet(void) const

Check if a value has been assigned to data member.

bool CanGetB(void) const

Check if it is safe to call GetB method.

bool IsSetStrand(void) const

Check if a value has been assigned to Strand data member.

Tdata & Set(void)

Assign a value to data member.

bool IsSetFuzz_to(void) const

Check if a value has been assigned to Fuzz_to data member.

void Reset(void)

Reset data member.

Tdata & Set(void)

Assign a value to data member.

void ResetFrom(void)

Reset From data member.

const TPoints & GetPoints(void) const

Get the Points member data.

TStrand GetStrand(void) const

Get the Strand member data.

bool IsSetId(void) const

WARNING: this used to be optional Check if a value has been assigned to Id data member.

TTo GetTo(void) const

Get the To member data.

bool IsSetFrom(void) const

Check if a value has been assigned to From data member.

bool IsInt(void) const

Check if variant Int is selected.

const TInt & GetInt(void) const

Get the variant data.

bool IsNull(void) const

Check if variant Null is selected.

void SetB(TB &value)

Assign a value to B data member.

bool IsSetId(void) const

Check if a value has been assigned to Id data member.

bool IsSetFuzz_from(void) const

Check if a value has been assigned to Fuzz_from data member.

const TFuzz & GetFuzz(void) const

Get the Fuzz member data.

const TMix & GetMix(void) const

Get the variant data.

void ResetTo(void)

Reset To data member.

bool IsPnt(void) const

Check if variant Pnt is selected.

bool IsSetB(void) const

other end may not be available Check if a value has been assigned to B data member.

const TPacked_int & GetPacked_int(void) const

Get the variant data.

const TBond & GetBond(void) const

Get the variant data.

bool CanGetFrom(void) const

Check if it is safe to call GetFrom method.

bool CanGetFuzz_from(void) const

Check if it is safe to call GetFuzz_from method.

@ eNa_strand_both_rev

in reverse orientation

@ e_not_set

No variant selected.

@ e_Equiv

equivalent sets of locations

@ e_Empty

to NULL one Seq-id in a collection

@ e_Feat

indirect, through a Seq-feat

TRepr GetRepr(void) const

Get the Repr member data.

const TInst & GetInst(void) const

Get the Inst member data.

bool IsSetRepr(void) const

Check if a value has been assigned to Repr data member.

bool IsSetExt(void) const

extensions for special types Check if a value has been assigned to Ext data member.

bool IsSetInst(void) const

the sequence data Check if a value has been assigned to Inst data member.

TLength GetLength(void) const

Get the Length member data.

bool IsDelta(void) const

Check if variant Delta is selected.

const TExt & GetExt(void) const

Get the Ext member data.

const TDelta & GetDelta(void) const

Get the variant data.

const Tdata & Get(void) const

Get the member data.

list< CRef< CDelta_seq > > Tdata

@ eRepr_delta

sequence made by changes (delta) to others

unsigned int

A callback function used to compare two keys in a database.

CRef< CSeq_loc > SeqLocExtend5(const CSeq_loc &loc, TSeqPos pos, CScope *scope)

bool IsExtendableRight(TSeqPos right, const CBioseq &seq, CScope *scope, TSeqPos &extend_len)

bool IsExtendableLeft(TSeqPos left, const CBioseq &seq, CScope *scope, TSeqPos &extend_len)

void AdjustFrameFor5Extension(CSeq_feat &feat, size_t diff)

bool OkToAdjustLoc(const CSeq_interval &interval, const CSeq_id *seqid)

void SeqLocAdjustForInsert(CSeq_interval &interval, TSeqPos insert_from, TSeqPos insert_to, const CSeq_id *seqid)

void CdregionAdjustForTrim(CCdregion &cdr, TSeqPos from, TSeqPos to, const CSeq_id *seqid)

void ReverseComplementCDRegion(CCdregion &cdr, CScope &scope)

bool AdjustFeatureEnd3(CSeq_feat &cds, vector< CRef< CSeq_feat > > related_features, CScope &scope)

void FeatureAdjustForInsert(CSeq_feat &feat, TSeqPos from, TSeqPos to, const CSeq_id *seqid)

bool ExtendPartialFeatureEnds(CBioseq_Handle bsh)

bool s_StrandsConsistent(const CSeq_interval &a, const CSeq_interval &b)

void ReverseComplementFeature(CSeq_feat &feat, CScope &scope)

bool s_PPntCompareMinus(const TSeqPos &p1, const TSeqPos &p2)

string PrintSeqIntUseBestID(const CSeq_interval &seq_int, CScope &scope, bool range_only)

void TrnaAdjustForTrim(CTrna_ext &trna, TSeqPos from, TSeqPos to, const CSeq_id *seqid)

void SeqLocAdjustForTrim(CSeq_interval &interval, TSeqPos cut_from, TSeqPos cut_to, const CSeq_id *seqid, bool &bCompleteCut, TSeqPos &trim5, bool &bAdjusted)

void NormalizeLoc(CSeq_loc &loc)

bool CorrectIntervalOrder(CPacked_seqpnt &ppnt)

bool AdjustFeatureEnd5(CSeq_feat &cds, vector< CRef< CSeq_feat > > related_features, CScope &scope)

string PrintBestSeqId(const CSeq_id &sid, CScope &scope)

void TrnaAdjustForInsert(CTrna_ext &trna, TSeqPos from, TSeqPos to, const CSeq_id *seqid)

bool OneIdOneStrand(const CSeq_loc &loc, const CSeq_id **id, ENa_strand &strand)

void ReverseComplementLocation(CSeq_interval &interval, CScope &scope)

bool ApplyPolicyToFeature(const CLocationEditPolicy &policy, const CSeq_feat &orig_feat, CScope &scope, bool adjust_gene, bool retranslate_cds)

bool IsExtendable(const CSeq_feat &cds, CScope &scope)

string SeqLocPrintUseBestID(const CSeq_loc &seq_loc, CScope &scope, bool range_only)

CRef< CSeq_loc > SeqLocExtend3(const CSeq_loc &loc, TSeqPos pos, CScope *scope)

string PrintPntAndPntsUseBestID(const CSeq_loc &seq_loc, CScope &scope, bool range_only)

bool s_PPntComparePlus(const TSeqPos &p1, const TSeqPos &p2)

void FeatureAdjustForTrim(CSeq_feat &feat, TSeqPos from, TSeqPos to, const CSeq_id *seqid, bool &bCompleteCut, bool &bTrimmed)

void CdregionAdjustForInsert(CCdregion &cdr, TSeqPos from, TSeqPos to, const CSeq_id *seqid)

static const string strand_symbol[]

void ReverseComplementTrna(CTrna_ext &trna, CScope &scope)

CRef< CSeq_interval > SplitLocationForGap(CSeq_interval &before, TSeqPos start, TSeqPos stop, const CSeq_id *seqid, bool &cut, unsigned int options)

CRef< CSeq_loc > SeqLocExtend(const CSeq_loc &loc, size_t pos, CScope *scope)

@ eSplitLocOption_split_in_intron

@ eSplitLocOption_make_partial

@ eSplitLocOption_split_in_exon

Portable reference counted smart and weak pointers using CWeakRef, CRef, CObject and CObjectEx.

Generic utility macros and templates for exploring NCBI objects.

bool seq_mac_is_sorted(Iter first, Iter last, Comp comp)

static SLJIT_INLINE sljit_ins l(sljit_gpr r, sljit_s32 d, sljit_gpr x, sljit_gpr b)


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