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Showing content from http://www.ncbi.nlm.nih.gov/IEB/ToolBox/CPP_DOC/doxyhtml/hmm_8cpp_source.html below:

NCBI C++ ToolKit: src/algo/gnomon/hmm.cpp Source File

51  int i

= (

l

-1)/m_step;

52  int

delx =

min

((

i

+1)*m_step,MaxLen())-

l

;

53  double

dely = (

i

== 0 ? 1 : m_clscore[

i

-1])-m_clscore[

i

];

54  return log

(dely/m_step*delx+m_clscore[

i

]);

58

: m_stop(point), m_strand(strn),

59

m_score(

BadScore

()), m_leftstate(0), m_terminal(0),

110

:

CHMM_State

(strn,point,seqscr), m_phase(ph),

111

m_prevexon(0), m_mscore(

BadScore

()),

112

m_param(&exon_params)

124  if

(frame < 0) frame += 3;

140  if

(frame < 0) frame += 3;

156  if

(frame < 0) frame += 3;

176

:

CExon

(strn,point,2,seqscr,exon_params)

202

:

CExon

(strn,point,ph,seqscr,exon_params)

235  if

((ph+1)%3 ==

next

.Phase())

return

0;

240

:

CExon

(strn,point,ph,seqscr,exon_params)

254

ph0 = (ph1-

last

)%3;

255  if

(ph0 < 0) ph0 += 3;

260

ph1 = (ph0+

last

)%3;

273

:

CExon

(strn,point,ph,seqscr,exon_params)

307

:

CHMM_State

(strn,point,seqscr), m_phase(ph),

308

m_param(&intron_params)

327  int

shift =

next

.Stop()-

next

.Start();

342

m_param(&intergenic_params)

403

CMarkov_chain_params::TProbabilities::const_iterator

i

= from.

GetProbabilities

().begin();

404

m_score[

enA

] = (*

i

++)->GetValue();

405

m_score[

enC

] = (*

i

++)->GetValue();

406

m_score[

enG

] = (*

i

++)->GetValue();

407

m_score[

enT

] = (*

i

++)->GetValue();

410

m_score[

enN

] = 0.25*(m_score[

enA

]+m_score[

enC

]+m_score[

enG

]+m_score[

enT

]);

419

m_score[

enN

] = 0.25*(m_score[

enA

]+m_score[

enC

]+m_score[

enG

]+m_score[

enT

]);

448  if

(first < 0 || last >= (

int

)seq.size())

return BadScore

();

470  if

((seq[

i

+1] !=

enT

|| seq[

i

+2] !=

enA

|| seq[

i

+3] !=

enA

) &&

471

(seq[

i

+1] !=

enT

|| seq[

i

+2] !=

enA

|| seq[

i

+3] !=

enG

) &&

522  for

(

int i

= 0;

i

< num; ++

i

)

m_score

[

i

] /= sum;

525  for

(

int i

= num-2;

i

>= 0; --

i

)

528  for

(

int i

= 0;

i

< num; ++

i

)

538  if

(seqlen >=

MinLen

()) {

543

through = (l2-2*seqlen)*w/2*exp(

m_score

[ifirst]);

546  int

ilast = (seqlen-1)/

m_step

;

547  for

(

int i

= 0;

i

< ilast; ++

i

) {

554  int

w = seqlen-ilast*

m_step

;

555  int

l2 = ilast*

m_step

+1+seqlen;

556

through += (l2-2*seqlen)*w/2*exp(

m_score

[ilast]);

560

through = (

AvLen

()-seqlen-through)/

AvLen

();

561

through = (through <= 0) ?

BadScore

() :

log

(through);

575  Error

(

label

+

" Too long First_exon_phase_probabilities"

);

582  for

(

int i

= 0;

i

< 3; ++

i

) {

583  for

(

int

j = 0; j < 3; ++j) {

588  Error

(

label

+

" Too long Internal_exon_phase_probabilities"

);

624  for

(

int i

= 0;

i

< 3; ++

i

)

662  ITERATE

(vector<CInputModel*>,

i

, all_created_models)

664

all_created_models.clear();

671  if

(

i

->second.empty())

672  i

->second.push_back(make_pair<int,CInputModel*>(101,

NULL

));

682

TCGContentList::iterator

i

= list.begin();

683  while

(

i

->first <= low ) {

689  i

= list.insert(

i

, *

i

);

694  if

(high < i->

first

) {

695  i

= list.insert(

i

, *

i

);

697

}

else if

(high >

i

->first) {

701  i

->second = input_model;

720 template

<

class

CParam>

724  if

((*p)->GetParam().Which() != choice)

727  int

low = (*p)->GetGc_content_range().GetFrom();

728  int

high = (*p)->GetGc_content_range().GetTo();

729  if

(!( 0<=low && low < high && high <= 100) )

733  if

(input_model==

NULL

)

736

all_created_models.push_back(input_model);

738

StoreParam(CParam::class_id(), input_model, low, high);

744

DeleteAllCreatedModels();

767  else if

(cgcontent >= 100)

771  if

(i_param == params.end())

775  if

(cgcontent < i->

first

) {

776  if

(

i

->second ==

NULL

) {

785  return

*params.begin()->second.front().second;

double m_internalphase[3][3]

CExonParameters(const objects::CGnomon_param::C_Param &from)

void UpdatePrevExon(const CExon &e)

const CExonParameters * m_param

CExon(EStrand strn, int point, int ph, const CSeqScores &seqscr, const CExonParameters &params)

double BranchScore(const CHMM_State &) const

CFirstExon(EStrand strn, int ph, int point, const CSeqScores &seqscr, const CExonParameters &params)

double LengthScore() const

void DeleteAllCreatedModels()

void ReadParameters(const objects::CGnomon_params &hmm_params_asn, objects::CGnomon_param::C_Param::E_Choice choice)

vector< pair< int, CInputModel * > > TCGContentList

TCGContentList & GetCGList(const string &type)

void StoreParam(const string &type, CInputModel *input_model, int low, int high)

SDetails(const objects::CGnomon_params &hmm_params_asn)

const CInputModel & GetParameter(const string &type, int cgcontent) const

CHMMParameters(const objects::CGnomon_params &hmm_params_asn)

CRef< SDetails > m_details

const CInputModel & GetParameter(const string &type, int cgcontent) const

const CSeqScores * m_seqscr

const CTerminal * m_terminal

CHMM_State(EStrand strn, int point, const CSeqScores &seqscr)

const CHMM_State * m_leftstate

static void Error(const string &label)

void SetSeqLen(int seqlen) const

CIntergenicParameters(const objects::CGnomon_param::C_Param &from)

CIntergenic(EStrand strn, int point, const CSeqScores &seqscr, const CIntergenicParameters &params)

double BranchScore(const CHMM_State &) const

const CIntergenicParameters * m_param

double LengthScore() const

CInternalExon(EStrand strn, int ph, int point, const CSeqScores &seqscr, const CExonParameters &params)

void SetSeqLen(int seqlen) const

CIntronParameters(const objects::CGnomon_param::C_Param &from)

const CIntronParameters * m_param

double BranchScore(const CHMM_State &) const

CIntron(int j_in, char amin_in, char don11, char don21, char acs11, char acs21, const CAlignInfo &prev, const CAlignInfo &cur, const CNSeq &nseq_in, const CProSplignScaledScoring &scoring)

double ClosingLengthScore() const

double LengthScore() const

CLastExon(EStrand strn, int ph, int point, const CSeqScores &seqscr, const CExonParameters &params)

double BranchScore(const CHMM_State &) const

CLength_distribution_params –.

double Score(int l) const

void Init(const objects::CLength_distribution_params &from)

double Through(int seqlen) const

double ClosingScore(int l) const

void InitScore(int l, const objects::CMarkov_chain_array &from)

double Score(const EResidue *seq) const

void Init(const objects::CMarkov_chain_params &hmm_param_asn)

void InitScore(const objects::CMarkov_chain_params &hmm_param_asn)

void Average(Type &mc0, Type &mc1, Type &mc2, Type &mc3)

CMarkov_chain_params –.

bool OpenCodingRegion(int a, int b, int strand, int frame) const

const CTerminal & Acceptor() const

const CTerminal & Stop() const

double StartScore(int i, int strand) const

bool OpenIntergenicRegion(int a, int b) const

double IntergenicScore(int a, int b, int strand) const

const CTerminal & Start() const

double AcceptorScore(int i, int strand) const

double CodingScore(int a, int b, int strand, int frame) const

double DonorScore(int i, int strand) const

const CTerminal & Donor() const

bool StopInside(int a, int b, int strand, int frame) const

double StopScore(int i, int strand) const

double BranchScore(const CHMM_State &) const

double LengthScore() const

CSingleExon(EStrand strn, int point, const CSeqScores &seqscr, const CExonParameters &params)

double Score(const CEResidueVec &seq, int i) const

CWAM_Stop(const objects::CGnomon_param::C_Param &from)

CMarkovChainArray< 1 > m_matrix

CWMM_Start(const objects::CGnomon_param::C_Param &from)

CMarkovChainArray< 0 > m_matrix

double Score(const CEResidueVec &seq, int i) const

container_type::const_iterator const_iterator

container_type::iterator iterator

static DLIST_TYPE *DLIST_NAME() first(DLIST_LIST_TYPE *list)

static DLIST_TYPE *DLIST_NAME() last(DLIST_LIST_TYPE *list)

static DLIST_TYPE *DLIST_NAME() next(DLIST_LIST_TYPE *list, DLIST_TYPE *item)

#define ITERATE(Type, Var, Cont)

ITERATE macro to sequence through container elements.

#define NCBI_THROW(exception_class, err_code, message)

Generic macro to throw an exception, given the exception class, error code and message string.

ESerialDataFormat

Data file format.

static CObjectIStream * Open(ESerialDataFormat format, CNcbiIstream &inStream, bool deleteInStream)

Create serial object reader and attach it to an input stream.

#define END_NCBI_SCOPE

End previously defined NCBI scope.

#define END_SCOPE(ns)

End the previously defined scope.

#define BEGIN_NCBI_SCOPE

Define ncbi namespace.

#define BEGIN_SCOPE(ns)

Define a new scope.

IO_PREFIX::istream CNcbiIstream

Portable alias for istream.

static const char label[]

list< double > TFirst_exon_phase_probabilities

TMin GetMin(void) const

Get the Min member data.

TL GetL(void) const

Get the L member data.

const TSingle_exon_length & GetSingle_exon_length(void) const

Get the Single_exon_length member data.

const TLast_exon_length & GetLast_exon_length(void) const

Get the Last_exon_length member data.

TA GetA(void) const

Get the A member data.

const Tdata & Get(void) const

Get the member data.

TStep GetStep(void) const

Get the Step member data.

const TRange & GetRange(void) const

Get the Range member data.

const TStop & GetStop(void) const

Get the variant data.

const TLength & GetLength(void) const

Get the Length member data.

const TInternal_exon_length & GetInternal_exon_length(void) const

Get the Internal_exon_length member data.

const TStart & GetStart(void) const

Get the variant data.

TIn_intron GetIn_intron(void) const

Get the In_intron member data.

TTo_term GetTo_term(void) const

Get the To_term member data.

const TIntron & GetIntron(void) const

Get the variant data.

const TFirst_exon_length & GetFirst_exon_length(void) const

Get the First_exon_length member data.

TTo_single GetTo_single(void) const

Get the To_single member data.

TIn_exon GetIn_exon(void) const

Get the In_exon member data.

const TP & GetP(void) const

Get the P member data.

TInitp GetInitp(void) const

Get the Initp member data.

const TFirst_exon_phase_probabilities & GetFirst_exon_phase_probabilities(void) const

Get the First_exon_phase_probabilities member data.

TMax GetMax(void) const

Get the Max member data.

list< double > TPhase_probabilities

E_Choice

Choice variants.

const TProbabilities & GetProbabilities(void) const

Get the Probabilities member data.

TInitp GetInitp(void) const

Get the Initp member data.

const TPhase_probabilities & GetPhase_probabilities(void) const

Get the Phase_probabilities member data.

const TLength & GetLength(void) const

Get the Length member data.

list< CRef< CGnomon_param > > Tdata

const TIntergenic & GetIntergenic(void) const

Get the variant data.

const TExon & GetExon(void) const

Get the variant data.

const TInternal_exon_phase_probabilities & GetInternal_exon_phase_probabilities(void) const

Get the Internal_exon_phase_probabilities member data.

TOrder GetOrder(void) const

Get the Order member data.

@ e_Coding_region

three elements (per phase)

void EvaluateInitialScore(State &r)

The blob sat and sat key Both must be positive integers</td > n< td > Non empty string The interpretation of the blob id depends on a processor Cassandra n processor expects the following format

static SLJIT_INLINE sljit_ins l(sljit_gpr r, sljit_s32 d, sljit_gpr x, sljit_gpr b)


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