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NCBI C++ ToolKit: src/objtools/cleanup/cleanup.cpp Source File

128 #define CLEANUP_SETUP \ 129  auto changes = makeCleanupChange(options); \ 130  CNewCleanup_imp clean_i(changes, options); \ 131  clean_i.SetScope(*m_Scope); 136

clean_i.BasicCleanupSeqEntry(se);

144

clean_i.BasicCleanupSeqSubmit(ss);

152

clean_i.BasicCleanupSubmitblock(block);

160

clean_i.BasicCleanupBioseqSet(bss);

168

clean_i.BasicCleanupSeqAnnot(sa);

176

clean_i.BasicCleanupSeqFeat(sf);

184

clean_i.BasicCleanupBioSource(src);

242

clean_i.BasicCleanup(desc);

252  for

(

auto

& it : desc.

Set

()) {

253

clean_i.BasicCleanup(*it);

263

clean_i.ExtendedCleanupSeqEntry(se);

272

clean_i.ExtendedCleanupSeqSubmit(ss);

280

clean_i.ExtendedCleanupSeqAnnot(sa);

303

vector<string_view>

result

;

313 static

constexpr std::array<string_view, CCleanupChangeCore::eNumberofChangeTypes>

sm_ChangeDesc

= {

314  "Invalid Change Code"

,

317  "Clean Double Quotes"

,

320  "Clean Qualifiers List"

,

321  "Clean Dbxrefs List"

,

322  "Clean CitonFeat List"

,

323  "Clean Keywords List"

,

324  "Clean Subsource List"

,

325  "Clean Orgmod List"

,

328  "Change Feature Key"

,

329  "Normalize Authors"

,

330  "Change Publication"

,

331  "Change Qualifiers"

,

343  "Change Code Break"

,

344  "Change Genetic Code"

,

350  "Change WholeLocation"

,

352  "Change MolInfo Descriptor"

,

358  "Add Protein Feature"

,

368  "Remove Descriptor"

,

372  "Convert Feature to Descriptor"

,

374  "Change Feature Location"

,

375  "Remove Annotation"

,

378  "Add BioSource OrgMod"

,

379  "Add BioSource SubSource"

,

380  "Change BioSource Genome"

,

381  "Change BioSource Origin"

,

382  "Change BioSource Other"

,

384  "Remove Empty Publication"

,

387  "Change BioseqInst"

,

391  "Change Prot Names"

,

392  "Change Prot Activities"

,

394  "Change PCR Primers"

,

396  "Move To Prot Xref"

,

401  "Create Gene Nomenclature"

,

402  "Clean Seq-feat xref"

,

403  "Clean User-Object Or -Field"

,

404  "Letter Case Change"

,

405  "Change Bioseq-set Class"

,

406  "Unique Without Sort"

,

414  "Add NcbiCleanupObject"

,

416  "Trim Flanking Quotes"

,

417  "Clean Bioseq Title"

,

419  "Remove Dup BioSource"

,

421  "Trim Internal Semicolons"

,

423  "Convert Unstructured Org-ref Modifier"

,

425  "Move GO term to GeneOntology object"

,

460  return "mat_peptide"

;

463  return "preprotein"

;

466  return "sig_peptide"

;

469  return "transit_peptide"

;

472  return "propeptide"

;

493

new_feat->

SetQual

().push_back(q);

531

CSeq_feat::TQual::iterator it = feat.

SetQual

().begin();

532  while

(it != feat.

SetQual

().end()) {

533  if

((*it)->IsSetQual() &&

535  if

((*it)->IsSetVal() && !

NStr::IsBlank

((*it)->GetVal())) {

536

feat.

SetData

().SetProt().SetName().push_back((*it)->GetVal());

538

it = feat.

SetQual

().erase(it);

544  if

(feat.

SetQual

().empty()) {

552  const bool

feat_by_product =

true

;

572  if

(cdsScores.empty()) {

577  for

(

auto

cdsScore : cdsScores) {

580  return

cdsScore.second;

585  return

cdsScores.front().second;

611  if

(parent_bsh.

IsAa

()) {

617  bool

matched_by_product =

false

;

625

matched_by_product =

true

;

628  if

(!matched_by_product) {

637  bool

require_frame =

false

;

638  if

(!require_frame) {

640  if

((*id_it)->IsEmbl() || (*id_it)->IsDdbj()) {

641

require_frame =

true

;

655

new_feat->

Assign

(*orig_feat);

657

new_feat->

SetData

().SetProt().SetProcessed(processed);

666

new_feat->

SetData

().SetProt().SetName().push_back(

"unnamed"

);

675  if

(matched_by_product) {

699  if

((*annot_it)->IsFtable()) {

727  bool

any_change =

false

;

733  for

(

CFeat_CI

prot_it(*bi, sel); prot_it; ++prot_it) {

764  if

(scores.size() == 1) {

766

}

else if

(scores.size() == 0) {

771  if

(

g

->second.GetPointer() != gene.

GetPointer

() &&

782  if

(!

f

.IsSetXref()) {

785  bool

any_removed =

false

;

786

CSeq_feat::TXref::iterator xit =

f

.SetXref().begin();

787  while

(xit !=

f

.SetXref().end()) {

788  if

((*xit)->IsSetData() && (*xit)->GetData().IsGene() &&

790

xit =

f

.SetXref().erase(xit);

797  if

(

f

.IsSetXref() &&

f

.GetXref().empty()) {

807  bool

any_change =

false

;

811  if

(fi->IsSetXref()) {

813

new_feat->

Assign

(*(fi->GetOriginalSeq_feat()));

831  if

(!

f

.IsSetXref()) {

834  bool

any_removed =

false

;

835

CSeq_feat::TXref::iterator xit =

f

.SetXref().begin();

836  while

(xit !=

f

.SetXref().end()) {

837  if

((*xit)->IsSetData() && (*xit)->GetData().IsGene() &&

838

!(*xit)->GetData().GetGene().IsSuppressed()) {

839

xit =

f

.SetXref().erase(xit);

846  if

(

f

.IsSetXref() &&

f

.GetXref().empty()) {

867  bool

has_xref =

false

;

870  if

((*xit)->IsSetId() && (*xit)->GetId().IsLocal()) {

871  if

((*xit)->GetId().Equals(src.

GetId

())) {

910  if

(!

f

.IsSetId() || !

f

.IsSetXref()) {

915  if

((*xit)->IsSetId() && (*xit)->GetId().IsLocal()) {

918  if

(far_feats.size() == 1) {

952  if

( !

f

.Equals(*feat_ci->GetSeq_feat()) && feat_ci->GetSeq_feat()->IsSetData() && feat_ci->GetSeq_feat()->GetData().IsGene()

953

&& feat_ci->GetSeq_feat()->GetData().GetGene().IsSetLocus())

955

locus2 = feat_ci->GetSeq_feat()->GetData().GetGene().GetLocus();

957  if

(!locus1.empty() && !locus2.empty() && locus1 == locus2)

968  if

(!

f

.IsSetXref()) {

971  bool

any_removed =

false

;

972

CSeq_feat::TXref::iterator xit =

f

.SetXref().begin();

973  while

(xit !=

f

.SetXref().end()) {

974  if

((*xit)->IsSetData() && (*xit)->GetData().IsGene() &&

975

!(*xit)->GetData().GetGene().IsSuppressed() && !

FindMatchingLocusGene

(

f

, (*xit)->GetData().GetGene(), bsh)) {

976

xit =

f

.SetXref().erase(xit);

983  if

(

f

.IsSetXref() &&

f

.GetXref().empty()) {

1000  if

( !

f

.Equals(*feat_ci->GetSeq_feat()) && feat_ci->GetSeq_feat()->IsSetData() && feat_ci->GetSeq_feat()->GetData().IsGene()

1001

&& feat_ci->GetSeq_feat()->GetData().GetGene().IsSetLocus_tag())

1003

locus_tag2 = feat_ci->GetSeq_feat()->GetData().GetGene().GetLocus_tag();

1005  if

(!locus_tag1.empty() && !locus_tag2.empty() && locus_tag1 == locus_tag2)

1016  if

(!

f

.IsSetXref()) {

1019  bool

any_removed =

false

;

1020

CSeq_feat::TXref::iterator xit =

f

.SetXref().begin();

1021  while

(xit !=

f

.SetXref().end()) {

1022  if

((*xit)->IsSetData() && (*xit)->GetData().IsGene() &&

1024

xit =

f

.SetXref().erase(xit);

1025

any_removed =

true

;

1031  if

(

f

.IsSetXref() &&

f

.GetXref().empty()) {

1048  bool

changed =

false

;

1050  if

(pos < loc_start) {

1052  id

->Assign(*(loc.

GetId

()));

1057

}

else if

(pos > loc_stop) {

1059  id

->Assign(*(loc.

GetId

()));

1079  if

(new_loc->

IsMix

()) {

1080

last_interval = new_loc->

SetMix

().SetLastLoc();

1088

last_interval = new_loc;

1110

last_interval->

SetInt

().SetFrom(new_start);

1111

last_interval->

SetInt

().SetTo(new_stop);

1112

last_interval->

SetInt

().SetId().Assign(*

id

);

1121  const CSeq_loc

& loc =

f

.GetLocation();

1126  if

(

f

.IsSetData() &&

f

.GetData().IsCdregion())

1128  if

(

f

.GetData().GetCdregion().IsSetCode())

1129  code

= &(

f

.GetData().GetCdregion().GetCode());

1130  if

(

f

.GetData().GetCdregion().IsSetFrame())

1131

frame =

f

.GetData().GetCdregion().GetFrame();

1141  size_t len

= orig_len;

1151

vector_loc->

SetInt

().SetId().Assign(*(bsh.

GetId

().front().GetSeqId()));

1154

vector_loc->

SetInt

().SetFrom(0);

1155

vector_loc->

SetInt

().SetTo(stop +

mod

- 1);

1158

vector_loc->

SetInt

().SetFrom(stop -

mod

+ 1);

1164  size_t

usable_size = seq.

size

();

1166  if

(limit > 0 && usable_size > limit) {

1167

usable_size = limit;

1181  size_t

length = usable_size / 3;

1183  for

(

i

= 0;

i

< length; ++

i

) {

1185  for

(k = 0; k < 3; ++k, ++start) {

1202  bool

changed =

false

;

1209  if

(frame != new_frame) {

1210

cds.

SetData

().SetCdregion().SetFrame(new_frame);

1236  switch

( (seq_len % 3) + 1 ) {

1251  if

(frame != desired_frame) {

1252

frame = desired_frame;

1299  if

(!

f

.GetData().IsCdregion()) {

1318  if

(check_for_stop) {

1355

prot_ref.

SetName

().front() +=

"; "

;

1357

prot_ref.

SetName

().front() += protein_name;

1359

prot_ref.

SetName

().push_back(protein_name);

1366  bool

used_qual =

false

;

1368  for

(

auto

it = mrna.

SetQual

().begin(); it != mrna.

SetQual

().end(); it++) {

1370

(*it)->SetVal(protein_name);

1378

mrna.

SetData

().SetRna().SetRnaProductName(protein_name, remainder);

1388  for

(

auto

it = cds.

GetXref

().begin(); it != cds.

GetXref

().end(); it++) {

1389  if

((*it)->IsSetData() && (*it)->GetData().IsProt()) {

1395  for

(

auto

it = cds.

GetQual

().begin(); it != cds.

GetQual

().end(); it++) {

1410  for

(

auto

it = feat.

SetXref

().begin(); it != feat.

SetXref

().end(); it++) {

1411  if

((*it)->IsSetData() && (*it)->GetData().IsProt()) {

1418  for

(

auto

it = feat.

SetQual

().begin(); it != feat.

SetQual

().end(); it++) {

1421

(*it)->SetVal((*it)->GetVal() +

"; "

+ protein_name);

1423

(*it)->SetVal(protein_name);

1434  bool

added =

false

;

1457  if

((*it)->IsSetData() && (*it)->GetData().IsProt()) {

1466

xref->SetData().SetProt().SetName().push_back(protein_name);

1467

cds.

SetXref

().push_back(xref);

1475  if

(

prot

.IsSetName() && !

prot

.GetName().empty()) {

1476  return prot

.GetName().front();

1486  if

((*it)->IsSetData() && (*it)->GetData().IsProt()) {

1492  for

(

auto

it = cds.

GetQual

().begin(); it != cds.

GetQual

().end(); it++) {

1493  if

((*it)->IsSetQual() && (*it)->IsSetVal() &&

NStr::EqualNocase

((*it)->GetQual(),

"product"

)) {

1494  return

(*it)->GetVal();

1521  bool

any_change =

false

;

1539

}

catch

(

const

runtime_error&) {

1562  switch

(loc.

Which

()) {

1580  bool

this_is_last = is_last && (*it == mix.

Set

().back());

1581  if

((*it)->IsMix() || (*it)->IsPacked_int()) {

1589  if

(!this_is_last &&

1606  bool

this_is_last = is_last && (*it == pint.

Set

().back());

1627

new_feat->

Assign

(*(

f

->GetSeq_feat()));

1641  if

(!

f

.IsSetLocation()) {

1644  bool

partial =

false

;

1646  while

(li && !partial) {

1653  bool

changed =

false

;

1654  if

(

f

.IsSetPartial() &&

f

.GetPartial()) {

1661  f

.SetPartial(

true

);

1671  bool

changed =

false

;

1675  string

& ec_num = *ec_num_iter;

1676  size_t

tlen = ec_num.length();

1678  if

(tlen != ec_num.length()) {

1697  bool

changed =

false

;

1698

CProt_ref::TEc::iterator ec_num_iter = ec_num_list.begin();

1699  while

(ec_num_iter != ec_num_list.end()) {

1700  string

& ec_num = *ec_num_iter;

1701  size_t

tlen = ec_num.length();

1703  if

(tlen != ec_num.length()) {

1708

ec_num_iter = ec_num_list.erase(ec_num_iter);

1721  bool

any_change =

false

;

1724  if

(

f

->GetData().GetProt().IsSetEc()) {

1725  bool

this_change =

false

;

1727

new_feat->

Assign

(*(

f

->GetSeq_feat()));

1731

new_feat->

SetData

().SetProt().ResetEc();

1732

this_change =

true

;

1764  bool

check_outer_gene =

true

;

1769

check_outer_gene =

false

;

1772  if

(check_outer_gene) {

1779  if

(

len

> longest) {

1788  bool

changed =

false

;

1849  bool

needs_molinfo =

true

;

1853  if

((*it)->IsMolinfo()) {

1854

needs_molinfo =

false

;

1856

(!(*it)->GetMolinfo().IsSetBiomol() ||

1863  if

(needs_molinfo) {

1870

seq.

SetDescr

().Set().push_back(m);

1875

seq.

SetDescr

().Set().push_back(m);

1877

needs_molinfo =

false

;

1881  return

needs_molinfo;

1893  switch

(it->Which()) {

1907  string

new_defline = sequence::CDeflineGenerator().GenerateDefline(bsh, sequence::CDeflineGenerator::fIgnoreExisting);

1911  bool

modified = title_desc.

Set

().

SetTitle

() != new_defline;

1913

title_desc.

Set

().

SetTitle

().swap(new_defline);

1921  return

(desc.

IsUser

() &&

1928  if

(!descr.

IsSet

() || descr.

Get

().empty()) {

1932  auto

& elements = descr.

Set

();

1933  auto

it = elements.begin();

1936  while

(it != elements.end()) {

1938

it = elements.erase(it);

1955  if

(rval && seq_entry.

GetDescr

().

Get

().empty()) {

1956  if

(seq_entry.

IsSeq

()) {

1959  else if

(seq_entry.

IsSet

()) {

1977  if

(descr.

IsSet

()) {

1978  for

(

auto

pDesc : descr.

Set

()) {

1980

pDesc->SetUser().UpdateNcbiCleanup(ncbi_cleanup_version);

1988  auto

& user = pCleanupObject->SetUser();

1989

user.UpdateNcbiCleanup(ncbi_cleanup_version);

1990

descr.

Set

().push_back(pCleanupObject);

2000  if

((*it)->IsSource() && (*it)->GetSource().IsSetOrg()) {

2001

src_descs.push_back(*it);

2019  bool

any_changes =

false

;

2021

vector<CRef<COrg_ref> > rq_list;

2022

vector<const CSeqdesc* > src_descs;

2023

vector<CConstRef<CSeq_feat> > src_feats;

2026

vector<const CSeqdesc* >::iterator desc_it = src_descs.begin();

2027  while

(desc_it != src_descs.end()) {

2030

org->

Assign

((*desc_it)->GetSource().GetOrg());

2031

rq_list.push_back(org);

2042

rq_list.push_back(org);

2049  if

(rq_list.size() > 0) {

2053

CTaxon3_reply::TReply::const_iterator reply_it = reply->GetReply().begin();

2056

desc_it = src_descs.begin();

2058  while

(reply_it != reply->GetReply().end()

2059

&& desc_it != src_descs.end()) {

2060  if

((*reply_it)->IsData() &&

2061

!(*desc_it)->GetSource().GetOrg().Equals((*reply_it)->GetData().GetOrg())) {

2062

any_changes =

true

;

2064

desc->

SetSource

().

SetOrg

().Assign((*reply_it)->GetData().GetOrg());

2072

vector<CConstRef<CSeq_feat> >::iterator feat_it = src_feats.begin();

2073  while

(reply_it != reply->GetReply().end()

2074

&& feat_it != src_feats.end()) {

2075  if

((*reply_it)->IsData() &&

2076

!(*feat_it)->GetData().GetBiosrc().GetOrg().Equals((*reply_it)->GetData().GetOrg())) {

2077

any_changes =

true

;

2079

new_feat->

Assign

(**feat_it);

2080

new_feat->

SetData

().SetBiosrc().SetOrg().Assign((*reply_it)->GetData().GetOrg());

2108  if

(new_product.

Empty

()) {

2115

new_product->

SetDescr

().Set().push_back(molinfo);

2120

new_product->

SetId

().push_back(prot_id);

2123

prot_entry->

SetSeq

(*new_product);

2126  if

(!eh.

IsSet

()) {

2132  if

(!eh.

IsSet

()) {

2137  if

(

set

&&

set

->IsSetSeq_set()) {

2139  if

(

nuc

->IsSetDescr()) {

2141  auto

it =

nuc

->GetDescr().Get().begin();

2142  while

(it !=

nuc

->GetDescr().Get().end()) {

2143  if

(!(*it)->IsMolinfo() && !(*it)->IsTitle() && !(*it)->IsCreate_date()) {

2145  copy

->Assign(**it);

2147

neh.RemoveSeqdesc(**it);

2148  if

(

nuc

->IsSetDescr()) {

2149

it =

nuc

->GetDescr().Get().begin();

2172  if

(!bsh.

IsNa

()) {

2182  if

(!bsrc.IsSetOrg() || !bsrc.IsSetOrgname()) {

2186  if

(!orgname.IsSetGcode() && !orgname.IsSetMgcode() && !orgname.IsSetPgcode()) {

2191  bool

any_changed =

false

;

2195  for

(; feat_ci; ++feat_ci) {

2198  int

cdregionGenCode = (cds.

IsSetCode

() ?

2201  if

(cdregionGenCode != bioseqGenCode)

2208

new_feat->

Assign

(feat);

2211

new_cds.

SetCode

().SetId(bioseqGenCode);

2213

edit_handle.

Replace

(*new_feat);

2214

any_changed =

true

;

2226  const string

& sTitle,

2227  const string

& sOrganism,

2230

OrganellePos =

NPOS

;

2234  const string

sPattern =

" ["

+ sOrganism +

"]"

;

2236

answer = sTitle.length() - sPattern.length();

2243  if

(answer < 1 || answer ==

NPOS

) {

2249  if

(answer !=

NPOS

) {

2263  if

(possible_organelle_start_pos !=

NPOS

&&

2265

OrganellePos = possible_organelle_start_pos;

2277  const string

& sTitle,

2282

organelle_pos =

NPOS

;

2298  bool

is_cross_kingdom =

false

;

2310  if

(first_kingdom.empty()) {

2311

first_kingdom = te.

GetName

();

2313

is_cross_kingdom =

true

;

2314

second_kingdom = te.

GetName

();

2320  return

is_cross_kingdom;

2326  string

first_kingdom, second_kingdom;

2332  const string

& sTitle,

2337

organelle_pos =

NPOS

;

2342  if

((*it)->IsSetSubtype() && (*it)->IsSetSubname() &&

2346  if

(suffixPos !=

NPOS

) {

2356  if

(suffixPos !=

NPOS

) {

2365  if

(suffixPos !=

NPOS

) {

2373  if

(sep != string::npos) {

2382  if

(

names

.empty()) {

2386  auto

suffix_len = suffix.length();

2387  bool

change_made{

false

};

2388  for

(

auto

& name :

names

) {

2390

name.erase(

len

- suffix_len);

2392

change_made =

true

;

2404  if

(

NStr::IsBlank

(taxname) || taxname.starts_with(

"NAD"

sv)) {

2408  const string

taxname_in_brackets{

'['

+ taxname +

']'

};

2410  bool

change_made{

false

};

2414  for

(; annot_it; ++annot_it) {

2421  for

(; feat_it; ++feat_it) {

2425

change_made =

true

;

2428

pEditedFeat->SetData().SetProt().SetName() = move(temp_names);

2441  for

(

auto

id_handle : bsh.

GetId

()) {

2442  auto

pId = id_handle.GetSeqId();

2460  case

eCompleteness_partial:

2461  case

eCompleteness_no_left:

2462  case

eCompleteness_no_right:

2463  case

eCompleteness_no_ends:

2477  if

((! seq_descr.

IsSet

()) || (pMolinfoDesc && pSrcDesc)) {

2481  for

(

auto

pDesc : seq_descr.

Get

()) {

2485  if

((! pMolinfoDesc) && pDesc->IsMolinfo()) {

2486

pMolinfoDesc = pDesc;

2490

}

else if

((! pSrcDesc) && pDesc->IsSource()) {

2509  if

((! pMolinfoDesc) || (! pSrcDesc)) {

2511  if

(pParentSet && pParentSet.IsSetDescr()) {

2518  return

make_pair(pMolinfoDesc, pSrcDesc);

2526  if

(partialPos ==

NPOS

) {

2527

partialPos =

NStr::Find

(sTitle,

", partial ("

);

2534  if

(suffixPos ==

NPOS

) {

2539

sTitle.resize(suffixPos);

2540  if

(penult !=

NPOS

) {

2541

sTitle.resize(penult);

2547

partialPos != string::npos &&

2548

(partialPos == (sTitle.length() - 9)))

2550

sTitle.resize(partialPos);

2555  if

(bPartial && partialPos ==

NPOS

) {

2556

sTitle +=

", partial"

;

2563  if

(genome >= eGenome_chloroplast &&

2564

genome <= eGenome_chromatophore &&

2565

genome != eGenome_extrachrom &&

2566

genome != eGenome_transposon &&

2567

genome != eGenome_insertion_seq &&

2568

genome != eGenome_proviral &&

2569

genome != eGenome_virion &&

2570

genome != eGenome_chromosome) {

2573

sTitle +=

" ("

+

string

(organelle) +

")"

;

2577  const auto

& org = src.

GetOrg

();

2578  string

first_kingdom, second_kingdom;

2580

sTitle +=

" ["

+ first_kingdom +

"]["

+ second_kingdom +

"]"

;

2583  if

(org.IsSetTaxname()) {

2594  const auto

& desc_list = descr.

Get

();

2595  for

(

auto

it = desc_list.rbegin(); it != desc_list.rend(); ++it) {

2596  if

((*it)->IsTitle()) {

2623

molinfo_desc = molinfo_and_src.first;

2624

src_desc = molinfo_and_src.second;

2629  const auto

& org =

source

.GetOrg();

2632  if

(org.IsSetTaxname()) {

2646  string

title = title_desc->

GetTitle

();

2651  if

(title != title_desc->

GetTitle

()) {

2653

pNewTitleDesc->SetTitle() = move(title);

2674  if

(

prot

->GetData().GetProt().IsSetName() &&

2675

!

prot

->GetData().GetProt().GetName().empty()) {

2676  label

=

prot

->GetData().GetProt().GetName().front();

2677

}

else if

(

prot

->GetData().GetProt().IsSetDesc()) {

2678  label

=

prot

->GetData().GetProt().GetDesc();

2701  bool

any_change =

false

;

2705  if

((*xit)->IsSetId() && (*xit)->GetId().IsLocal()) {

2711  if

(f_start < gene_start) {

2713

gene_start = f_start;

2716  if

(f_stop > gene_stop) {

2732

{

"16S"

, { 1000,

false

} },

2733

{

"18S"

, { 1000,

false

} },

2734

{

"23S"

, { 2000,

false

} },

2735

{

"25S"

, { 1000,

false

} },

2736

{

"26S"

, { 1000,

false

} },

2737

{

"28S"

, { 3300,

false

} },

2738

{

"small"

, { 1000,

false

} },

2739

{

"large"

, { 1000,

false

} },

2740

{

"5.8S"

, { 130,

true

} },

2741

{

"5S"

, { 90,

true

} }

2752  bool

is_bad =

false

;

2754  const CRNA_ref

& rrna =

f

.GetData().GetRna();

2756  if

(rrna_name.empty()) {

2758  if

(

f

.IsSetQual()) {

2759  for

(

auto

qit :

f

.GetQual()) {

2762

rrna_name = gbq.

GetVal

();

2770  if

(pos != string::npos && len < it->second.first && !(it->second.second &&

f

.IsSetPartial() &&

f

.GetPartial()) ) {

2780  bool

any_changes =

false

;

2782  int

protein_id_counter = 1;

2786  for

(

CFeat_CI

cds_it(entry, sel); cds_it; ++cds_it) {

2787  bool

change_this_cds =

false

;

2789

new_cds->

Assign

(*(cds_it->GetSeq_feat()));

2807

new_cds->

SetProduct

().SetWhole().Assign(*new_id);

2808

change_this_cds =

true

;

2811  if

(new_cds->

IsSetProduct

() && instantiate_missing_proteins) {

2814

any_changes =

true

;

2827

new_inst->

SetSeq_data

().SetNcbieaa().Set(current);

2829

any_changes =

true

;

2835

current_name =

"hypothetical protein"

;

2836

change_this_cds =

true

;

2850  bool

change_mrna =

false

;

2852

new_mrna->

Assign

(*mrna);

2856  for

(

auto

it = new_mrna->

GetQual

().begin(); it != new_mrna->

GetQual

().end(); it++) {

2857  if

((*it)->IsSetQual() && (*it)->IsSetVal() &&

NStr::EqualNocase

((*it)->GetQual(),

"product"

)) {

2858

mrna_name = (*it)->GetVal();

2864

|| (!

NStr::Equal

(current_name,

"hypothetical protein"

) &&

2867

change_mrna =

true

;

2875

any_changes =

true

;

2881  if

(change_this_cds) {

2885

any_changes =

true

;

2895  const CSeq_feat

& rna_feat = *(rna_it->GetSeq_feat());

2900  bool

change_this_rrna =

false

;

2902

new_rrna->

Assign

(*(rna_it->GetSeq_feat()));

2909

change_this_rrna =

true

;

2913

change_this_rrna =

true

;

2918

change_this_rrna =

true

;

2922

change_this_rrna =

true

;

2926  if

(change_this_rrna) {

2929

any_changes =

true

;

2935  bool

change_this_gene =

false

;

2937

new_gene->

Assign

(*(gene_it->GetSeq_feat()));

2943  if

(change_this_gene) {

2946

any_changes =

true

;

2956  if

(run_extended_cleanup) {

2958  if

(pChanged->ChangeCount()>0) {

2969  while

(li && li.

IsEmpty

()) {

2986  while

(li && li.

IsEmpty

()) {

2999  if

(this_strand == prev_strand) {

3000  if

(

abs

((

long int

)this_start - (

long int

)prev_end) < min_len) {

3015  bool

any_change =

false

;

3033  bool

any_changes =

false

;

3036  for

(

CFeat_CI

cds_it(entry, sel); cds_it; ++cds_it) {

3037  bool

change_this_cds =

false

;

3039

new_cds->

Assign

(*(cds_it->GetSeq_feat()));

3045  if

(change_this_cds) {

3049

any_changes =

true

;

3104  const int

unknown_seqdesc =

static_cast<int>

(1 + sc_SeqdescOrderMap.size());

3107  if

(find_iter == sc_SeqdescOrderMap.end()) {

3108  return

unknown_seqdesc;

3111  return

find_iter->second;

3119

chs1 = desc1->

Which

();

3120

chs2 = desc2->

Which

();

3142  if

(

edit

.IsSetDescr()) {

3154  bool

removed =

false

;

3158  if

((*d)->IsTitle()) {

3163

last_title.

Reset

(d->GetPointer());

3173  bool

removed =

false

;

3174  if

(

set

.IsSetDescr()) {

3177  if

((*d)->IsTitle()) {

3179  set

.RemoveSeqdesc(*last_title);

3182

last_title.

Reset

(d->GetPointer());

3204  string

& auth_str = *out_authors;

3211

vector<string> name_list;

3215  if

((*auth_it)->IsSetName()) {

3217

(*auth_it)->GetName().GetLabel(&

label

);

3218

name_list.push_back(

label

);

3223

back_inserter(name_list));

3226

back_inserter(name_list));

3229  if

(name_list.size() == 0) {

3231

}

else if

(name_list.size() == 1) {

3232

auth_str = name_list.back();

3238

last_author.swap(name_list.back());

3239

name_list.pop_back();

3241  NStr::Join

(name_list,

", "

).swap(auth_str);

3242

auth_str +=

"and "

;

3243

auth_str += last_author;

3250  string

*out_authors_string,

const CPubdesc

& pd)

3252  string

& authors_string = *out_authors_string;

3253

authors_string.clear();

3256  if

((*pub)->IsSetAuthors()) {

3266

vector<TEntrezId>& pmids, vector<TEntrezId>& muids, vector<int>& serials,

3267

vector<string>& published_labels,

3268

vector<string>& unpublished_labels)

3271  bool

is_published =

false

;

3272  bool

need_label =

false

;

3278  if

((*it)->IsPmid()) {

3279

pmids.push_back((*it)->GetPmid());

3280

is_published =

true

;

3281

}

else if

((*it)->IsMuid()) {

3282

muids.push_back((*it)->GetMuid());

3283

is_published =

true

;

3284

}

else if

((*it)->IsGen()) {

3285  if

((*it)->GetGen().IsSetCit()

3289  if

((*it)->GetGen().IsSetSerial_number()) {

3290

serials.push_back((*it)->GetGen().GetSerial_number());

3291  if

((*it)->GetGen().IsSetCit()

3292

|| (*it)->GetGen().IsSetJournal()

3293

|| (*it)->GetGen().IsSetDate()) {

3299

}

else if

((*it)->IsArticle() && (*it)->GetArticle().IsSetIds()) {

3300

is_published =

true

;

3302  if

((*id)->IsPubmed()) {

3303

pmids.push_back((*id)->GetPubmed());

3304

is_published =

true

;

3305

}

else if

((*id)->IsMedline()) {

3306

muids.push_back((*id)->GetMedline());

3324

published_labels.push_back(

label

);

3326

unpublished_labels.push_back(

label

);

3334

vector<CConstRef<CPub> > pub_list;

3339

vector<TEntrezId> pmids;

3340

vector<TEntrezId> muids;

3341

vector<int> serials;

3342

vector<string> published_labels;

3343

vector<string> unpublished_labels;

3345  if

(pmids.size() > 0) {

3348

pub_list.push_back(pub);

3349

}

else if

(muids.size() > 0) {

3352

pub_list.push_back(pub);

3353

}

else if

(serials.size() > 0) {

3356

pub_list.push_back(pub);

3357

}

else if

(published_labels.size() > 0) {

3360

pub_list.push_back(pub);

3361

}

else if

(unpublished_labels.size() > 0) {

3364

pub_list.push_back(pub);

3372

vector<TEntrezId> pmids;

3373

vector<TEntrezId> muids;

3374

vector<int> serials;

3375

vector<string> published_labels;

3376

vector<string> unpublished_labels;

3378  if

(pmids.size() > 0) {

3381

pub_list.push_back(pub);

3382

}

else if

(muids.size() > 0) {

3385

pub_list.push_back(pub);

3386

}

else if

(serials.size() > 0) {

3389

pub_list.push_back(pub);

3390

}

else if

(published_labels.size() > 0) {

3393

pub_list.push_back(pub);

3394

}

else if

(unpublished_labels.size() > 0) {

3397

pub_list.push_back(pub);

3408  bool

any_change =

false

;

3409

CSeq_descr::Tdata::iterator it1 = descr.

Set

().begin();

3410  while

(it1 != descr.

Set

().end()) {

3411  if

((*it1)->IsPub()) {

3412

CSeq_descr::Tdata::iterator it2 = it1;

3414  while

(it2 != descr.

Set

().end()) {

3415  if

((*it2)->IsPub() && (*it1)->GetPub().Equals((*it2)->GetPub())) {

3416

it2 = descr.

Set

().erase(it2);

3435  if

(pd1.

GetPub

().

Get

().front()->Equals(**it)) {

3457  bool

is_embl_or_ddbj =

false

;

3459  if

((*id)->IsEmbl() || (*id)->IsDdbj()) {

3460

is_embl_or_ddbj =

true

;

3464  return

!is_embl_or_ddbj;

3488

}

else if

(parent && parent.

IsSetClass

() &&

3515  bool

any_change =

false

;

3518  if

(p->GetLocation().IsInt() &&

3523  if

(p->IsSetComment()) {

3556  bool

found_non_minimal =

false

;

3558  if

((*it)->IsMuid() || (*it)->IsPmid()) {

3559  if

(is_refseq_prot) {

3560

found_non_minimal =

true

;

3563

}

else if

((*it)->IsGen()) {

3565  if

(

gen

.IsSetCit() && !

gen

.IsSetJournal() &&

3566

!

gen

.IsSetAuthors() && !

gen

.IsSetVolume() &&

3567

!

gen

.IsSetPages()) {

3570

found_non_minimal =

true

;

3573

found_non_minimal =

true

;

3578  return

!found_non_minimal;

3584  bool

found_site_ref =

false

;

3586  while

(

f

&& !found_site_ref) {

3588

found_site_ref =

true

;

3592  if

(!found_site_ref) {

3596  bool

any_change =

false

;

3598  bool

is_refseq_prot =

false

;

3601  if

((*id_it)->IsOther()) {

3602

is_refseq_prot =

true

;

3613  bool

is_site_ref =

IsSiteRef

(*(p->GetSeq_feat()));

3616  if

((*c)->IsEquiv()) {

3685  if

(chs1 < chs2)

return true

;

3686  if

(chs1 > chs2)

return false

;

3715  const string

& n1 = s1.

GetName

();

3716  const string

& n2 = s2.

GetName

();

3737

CBioSource::TSubtype::iterator s = biosrc.

SetSubtype

().begin();

3738

CBioSource::TSubtype::iterator s_next = s;

3740  while

(s_next != biosrc.

SetSubtype

().end()) {

3756  bool

any_change =

false

;

3797  bool

any_change =

false

;

3804

on1.

SetMod

().push_back(

a

);

3853  bool

any_change =

false

;

3857  if

(!

HasMod

(org1, *it)) {

3858

org1.

SetMod

().push_back(*it);

3869

org1.

SetDb

().push_back(

a

);

3877

org1.

SetSyn

().push_back(*it);

3892  bool

any_change =

false

;

3893

CSeq_descr::Tdata::iterator src1 = seq_descr.

Set

().begin();

3894  while

(src1 != seq_descr.

Set

().end()) {

3895  if

((*src1)->IsSource() && (*src1)->GetSource().IsSetOrg() && (*src1)->GetSource().GetOrg().IsSetTaxname()) {

3896

CSeq_descr::Tdata::iterator src2 = src1;

3898  while

(src2 != seq_descr.

Set

().end()) {

3899  if

((*src2)->IsSource() &&

3906

src2 = seq_descr.

Set

().erase(src2);

3921  bool

any_change =

false

;

3922

vector<CConstRef<CBioSource> > src_list;

3923

CSeq_descr::Tdata::iterator d = descr.

Set

().begin();

3924  while

(d != descr.

Set

().end()) {

3925  if

((*d)->IsSource()) {

3926  bool

found =

false

;

3928  if

((*d)->GetSource().Equals(**s)) {

3934

d = descr.

Set

().erase(d);

3938

src_list.push_back(src);

3951  if

(!

f

.IsSetData() || !

f

.GetData().IsBiosrc()) {

3955

src->

Assign

(

f

.GetData().GetBiosrc());

3958  if

(

f

.IsSetComment()) {

3967  if

(

f

.IsSetDbxref()) {

3971

src->

SetOrg

().SetDb().push_back(

a

);

3984  bool

any_change =

false

;

3986  bool

transgenic_or_focus =

false

;

3988  while

(existing_src && !transgenic_or_focus) {

3991

transgenic_or_focus =

true

;

3995  if

(transgenic_or_focus) {

3999  if

(p->GetLocation().IsInt() &&

4043  size_t

num_gene_locus = 0;

4044  size_t

num_gene_locus_tag = 0;

4045  size_t

num_gene_xref_locus = 0;

4046  size_t

num_gene_xref_locus_tag = 0;

4054

num_gene_locus_tag++;

4059  if

(

g

->IsSetLocus()) {

4060

num_gene_xref_locus++;

4062  if

(

g

->IsSetLocus_tag()) {

4063

num_gene_xref_locus_tag++;

4067  if

(num_gene_locus > 0) {

4068  if

(num_gene_locus_tag > 0) {

4071  if

(num_gene_xref_locus > 0) {

4075  if

(num_gene_locus_tag > 0) {

4076  if

(num_gene_locus > 0) {

4079  if

(num_gene_xref_locus_tag > 0) {

4086  bool

any_change =

false

;

4087  if

(num_gene_locus == 0 && num_gene_locus_tag > 0) {

4088  if

(num_gene_xref_locus > 0 && num_gene_xref_locus_tag == 0) {

4092  bool

this_change =

false

;

4096  if

((*it)->IsSetData() && (*it)->GetData().IsGene()

4097

&& (*it)->GetData().GetGene().IsSetLocus()) {

4098

(*it)->SetData().SetGene().SetLocus_tag((*it)->GetData().GetGene().GetLocus());

4099

(*it)->SetData().SetGene().ResetLocus();

4100

this_change =

true

;

4111

}

else if

(num_gene_locus > 0 && num_gene_locus_tag == 0) {

4112  if

(num_gene_xref_locus == 0 && num_gene_xref_locus_tag > 0) {

4116  bool

this_change =

false

;

4120  if

((*it)->IsSetData() && (*it)->GetData().IsGene()

4121

&& (*it)->GetData().GetGene().IsSetLocus_tag()) {

4122

(*it)->SetData().SetGene().SetLocus((*it)->GetData().GetGene().GetLocus_tag());

4123

(*it)->SetData().SetGene().ResetLocus_tag();

4124

this_change =

true

;

4143  bool

strip_serial =

true

;

4146  switch

(sid.

Which

()) {

4152  const string

& acc =

GET_FIELD

(tsid, Accession);

4153  if

(acc.length() == 6) {

4154

strip_serial =

false

;

4161

strip_serial =

false

;

4178

strip_serial =

false

;

4184  return

strip_serial;

4190  bool

change_made =

false

;

4204

change_made =

true

;

4227  bool

change_made =

false

;

4234  if

(

NPOS

== amp ) {

4240  const static struct

{

4243

} transformations[] = {

4252

{

"#13;&#10"

,

""

},

4253

{

"#916"

,

"Delta"

},

4254

{

"#945"

,

"alpha"

},

4255

{

"#946"

,

"beta"

},

4256

{

"#947"

,

"gamma"

},

4257

{

"#952"

,

"theta"

},

4258

{

"#955"

,

"lambda"

},

4266

{

"#8710"

,

"delta"

},

4267

{

"#64257"

,

"fi"

},

4268

{

"#64258"

,

"fl"

},

4282  for

(

unsigned

idx = 0; idx <

ArraySize

(transformations); ++idx) {

4284

searcher.

AddWord

(transformations[idx].src_word, idx);

4296  result

.reserve( str_len );

4298

back_inserter(

result

) );

4302  while

( amp !=

NPOS

&& amp < str_len ) {

4308  if

(

str

[search_pos] ==

' '

) {

4311  for

( ; search_pos < str_len ; ++search_pos ) {

4312  const char

ch =

str

[search_pos];

4316  if

( ch ==

'&'

&&

state

== 0 ) {

4328  const string

& result_word = transformations[match_idx].result_word;

4329  copy

( result_word.begin(), result_word.end(),

4330

back_inserter(

result

) );

4331

change_made =

true

;

4335  if

( search_pos >= str_len ) {

4339

back_inserter(

result

) );

4347  const string

& result_word = transformations[match_idx].result_word;

4348  copy

( result_word.begin(), result_word.end(),

4349

back_inserter(

result

) );

4350

change_made =

true

;

4354  copy

(

str

.begin() + amp,

str

.begin() + search_pos + 1,

4355

back_inserter(

result

) );

4359  if

(

str

[search_pos] ==

'&'

) {

4365  if

(

NPOS

== next_amp ) {

4367  copy

(

str

.begin() + search_pos + 1,

str

.end(),

4368

back_inserter(

result

) );

4373  if

( (search_pos + 1) < next_amp ) {

4374  copy

(

str

.begin() + search_pos + 1,

str

.begin() + next_amp,

4375

back_inserter(

result

) );

4390  if

(require_inframe) {

4392  bool

is_ok =

false

;

4393  switch

(is_in_frame) {

4423

new_loc = nuc2prot_mapper->

Map

(nuc_loc);

4430  if

(!sid || (orig_id && sid->

Equals

(*orig_id))) {

4450  if

(!new_loc->

IsInt

() && !new_loc->

IsPnt

()) {

4512  bool

changed =

false

;

4518  if

((*annot_it)->IsSetData() && (*annot_it)->IsFtable()) {

4520  if

((*feat_it)->IsSetData() && (*feat_it)->GetData().IsCdregion()) {

4535  bool

any_change =

false

;

4536  for

(

CBioseq_CI

bi(seh, filter); bi; ++bi) {

4561  if

(!feat_loc_seq_id) {

4566

string::size_type

len

= 0;

4567

string::size_type loc_pos, end_pos;

4568  char

protein_letter =

'X'

;

4571  if

(aa_pos == string::npos) {

4573  if

(aa_pos != string::npos) {

4576  if

(aa_pos != string::npos) {

4583  if

(aa_pos != string::npos) {

4599

[pMessageListener](

string msg

, TSubcode subcode) {

4604  if

(loc_pos == string::npos) {

4605  if

(pMessageListener) {

4606  string msg

=

"Unable to identify code-break location in '"

+

str

+

"'"

;

4607

postMessage(

msg

, TSubcode::eParseError);

4612  while

(loc_pos <

str

.length() &&

isspace

(

str

[loc_pos])) {

4617  if

(end_pos ==

NPOS

) {

4619  if

(end_pos ==

NPOS

) {

4620

end_pos =

str

.length();

4627  if

(pos.find_first_of(

","

) != string::npos) {

4628

pos =

"join("

+ pos +

")"

;

4634  if

(pMessageListener) {

4635  string msg

=

"Unable to extract code-break location from '"

+

str

+

"'"

;

4636

postMessage(

msg

, TSubcode::eParseError);

4642  if

(pMessageListener) {

4643  string msg

=

"code-break location exceeds 3 bases"

;

4644

postMessage(

msg

, TSubcode::eBadLocation);

4648  if

((break_loc->

IsInt

() || break_loc->

IsPnt

()) &&

4650  if

(pMessageListener) {

4651  string msg

=

"code-break location lies outside of coding region"

;

4652

postMessage(

msg

, TSubcode::eBadLocation);

4672

newCodeBreak->

SetLoc

(*break_loc);

4675

orig_list.push_back(newCodeBreak);

4688  bool

any_removed =

false

;

4689

CSeq_feat::TQual::iterator it = feat.

SetQual

().begin();

4690  while

(it != feat.

SetQual

().end()) {

4691  if

((*it)->IsSetQual() &&

4693

(*it)->IsSetVal() &&

4695

it = feat.

SetQual

().erase(it);

4696

any_removed =

true

;

4701  if

(feat.

GetQual

().size() == 0) {

4719  auto

it = flu_map.

find

(

key

);

4720  if

(it == flu_map.

end

()) {

4722

new_set->AddBioseq(*bi);

4723

flu_map[

key

] = new_set;

4725

it->second->AddBioseq(*bi);

4733  for

(

auto

& entry : flu_map) {

4734  if

(entry.second->OkToMakeSet()) {

4735

entry.second->MakeSet();

4749  for

(; annot_ci; ++annot_ci) {

4750  if

((*annot_ci).IsFtable()) {

4765  f

->SetData().SetImp().SetKey(

"misc_feature"

);

4766  f

->SetLocation().SetInt().SetFrom(0);

4768  f

->SetLocation().SetInt().SetId().Assign(*(bh.

GetSeqId

()));

4771  f

->SetDbxref().push_back(xref);

4773

suppress->SetData().SetGene();

4774  f

->SetXref().push_back(suppress);

4788

COrg_ref::TDb::iterator db = org->

SetDb

().begin();

4789  while

(db != org->

SetDb

().end()) {

4790  if

((*db)->IsSetDb() &&

NStr::Equal

((*db)->GetDb(),

"IRD"

)) {

4792

db = org->

SetDb

().erase(db);

4798  if

(org->

GetDb

().size() == 0) {

4862

default : frame = 0;

break

;

4867  if

(cb->IsSetLoc()) {

4871

((

offset

- frame) / 3 ) + 1 == pos) {

4884  int

start =

static_cast<int>

((pos-1)*3);

4896

default : frame = 0;

break

;

4899  int

frame_shift = (start - frame) % 3;

4900  if

(frame_shift < 0) {

4903  if

(frame_shift == 1)

4905  else if

(frame_shift == 2)

4911  int len

= loc_iter.GetRange().GetLength();

4912  if

(offset <= start && offset + len > start) {

4914  tmp

->SetId().Assign(loc_iter.GetSeq_id());

4917  tmp

->SetTo(loc_iter.GetRange().GetTo() - (start -

offset

) );

4919  tmp

->SetFrom(loc_iter.GetRange().GetFrom() + start -

offset

);

4921  if

(offset <= start + 2 && offset + len > start + 2) {

4923  tmp

->SetFrom(loc_iter.GetRange().GetTo() - (start -

offset

+ 2) );

4925  tmp

->SetTo(loc_iter.GetRange().GetFrom() + start -

offset

+ 2);

4929  tmp

->SetFrom(loc_iter.GetRange().GetFrom());

4931  tmp

->SetTo(loc_iter.GetRange().GetTo());

4938  tmp

->SetId().Assign(loc_iter.GetSeq_id());

4941  tmp

->SetTo(loc_iter.GetRange().GetTo());

4943  tmp

->SetFrom(loc_iter.GetRange().GetTo() - (start -

offset

+ 2) );

4945  tmp

->SetFrom(loc_iter.GetRange().GetFrom());

4948  tmp

->SetFrom(loc_iter.GetRange().GetFrom());

4950  tmp

->SetTo(loc_iter.GetRange().GetFrom() + start -

offset

+ 2);

4952  tmp

->SetTo(loc_iter.GetRange().GetTo());

4989  bool

any_change =

false

;

5010  bool

any_changes =

false

;

5012

vector<CRef<COrg_ref> > rq_list;

5013

vector<const CSeqdesc* > src_descs;

5014

vector<CConstRef<CSeq_feat> > src_feats;

5017

vector<const CSeqdesc* >::iterator desc_it = src_descs.begin();

5018  while

(desc_it != src_descs.end()) {

5019  if

((*desc_it)->GetSource().IsSetSubtype()) {

5023

&& s->IsSetName()) {

5024  bool

month_ambiguous =

false

;

5027

s->SetName(new_date);

5028

any_changes =

true

;

5041  bool

local_change =

false

;

5042  for

(

auto

s : new_feat->

SetData

().SetBiosrc().SetSubtype()) {

5044

&& s->IsSetName()) {

5045  bool

month_ambiguous =

false

;

5048

s->SetName(new_date);

5049

local_change =

true

;

5054

any_changes =

true

;

5071  bool

removed =

true

;

5076  if

(

ud

->GetUser().IsAutodefOptions()) {

@ eExtreme_Positional

numerical value

@ eExtreme_Biological

5' and 3'

User-defined methods of the data storage class.

User-defined methods of the data storage class.

CRef< objects::CSeq_id > GetNewProtId(objects::CBioseq_Handle bsh, int &offset, string &id_label, bool general_only)

bool IsGeneralIdProtPresent(objects::CSeq_entry_Handle tse)

@Auth_list.hpp User-defined methods of the data storage class.

CSeqdesc & Set(bool skip_lookup=false)

static CRef< CUser_object > CreateIDOptions(CSeq_entry_Handle seh)

static bool RegenerateSequenceDefLines(CSeq_entry_Handle se)

static string GetOrganelleByGenome(unsigned int genome)

int GetGenCode(int def=1) const

bool HasSubtype(CSubSource::TSubtype subtype) const

CBioseq_set_EditHandle –.

vector< EChanges > GetAllChanges() const

vector< string_view > GetDescriptions() const

static string_view GetDescription(EChanges e)

static bool RescueSiteRefPubs(CSeq_entry_Handle seh)

Rescue pubs from Site-ref features.

static bool ConvertDeltaSeqToRaw(CSeq_entry_Handle seh, CSeq_inst::EMol filter=CSeq_inst::eMol_not_set)

static bool RenormalizeNucProtSets(CSeq_entry_Handle seh)

Convert nuc-prot sets with just one sequence to just the sequence can't be done during the explore ph...

static bool ShouldStripPubSerial(const CBioseq &bs)

static char ValidAminoAcid(string_view abbrev)

static bool RemoveOrphanLocus_tagGeneXrefs(CSeq_feat &f, CBioseq_Handle bsh)

Removes orphaned locus_tag Gene-xrefs.

static bool FixGeneXrefSkew(CSeq_entry_Handle seh)

Examine all genes and gene xrefs in the Seq-entry.

static void MoveOneFeatToPubdesc(CSeq_feat_Handle feat, CRef< CSeqdesc > d, CBioseq_Handle b, bool remove_feat=true)

static bool AddGenBankWrapper(CSeq_entry_Handle seh)

Add GenBank Wrapper Set.

static bool ConvertPubFeatsToPubDescs(CSeq_entry_Handle seh)

Convert full-length publication features to publication descriptors.

static void SetProteinName(CProt_ref &prot, const string &protein_name, bool append)

static void s_SetProductOnFeat(CSeq_feat &feat, const string &protein_name, bool append)

static bool RemovePseudoProduct(CSeq_feat &cds, CScope &scope)

Removes protein product from pseudo coding region.

static bool FixECNumbers(CSeq_entry_Handle entry)

Fix EC numbers.

static bool AddMissingMolInfo(CBioseq &seq, bool is_product)

Adds missing MolInfo descriptor to sequence.

static void SetMrnaName(CSeq_feat &mrna, const string &protein_name)

static CRef< CSeq_entry > AddProtein(const CSeq_feat &cds, CScope &scope)

static bool OkToPromoteNpPub(const CPubdesc &pd)

Some pubs should not be promoted to nuc-prot set from sequence.

static void GetPubdescLabels(const CPubdesc &pd, vector< TEntrezId > &pmids, vector< TEntrezId > &muids, vector< int > &serials, vector< string > &published_labels, vector< string > &unpublished_labels)

For Publication Citations Get labels for a pubdesc.

static bool DecodeXMLMarkChanged(std::string &str)

decodes various tags, including carriage-return-line-feed constructs

static bool SetFeaturePartial(CSeq_feat &f)

Set feature partial based on feature location.

static bool AddProteinTitle(CBioseq_Handle bsh)

Creates missing protein title descriptor.

static size_t MakeSmallGenomeSet(CSeq_entry_Handle entry)

static bool ExtendToStopIfShortAndNotPartial(CSeq_feat &f, CBioseq_Handle bsh, bool check_for_stop=true)

Extends a coding region up to 50 nt.

static bool IsGeneXrefUnnecessary(const CSeq_feat &sf, CScope &scope, const CGene_ref &gene_xref)

Calculates whether a Gene-xref is unnecessary (because it refers to the same gene as would be calcula...

static bool ClearInternalPartials(CSeq_loc &loc, bool is_first=true, bool is_last=true)

Clear internal partials.

static bool RepackageProteins(CSeq_entry_Handle seh)

Find proteins that are not packaged in the same nuc-prot set as the coding region for which they are ...

CCleanup(CScope *scope=nullptr, EScopeOptions scope_handling=eScope_Copy)

static bool WGSCleanup(CSeq_entry_Handle entry, bool instantiate_missing_proteins=true, Uint4 options=0, bool run_extended_cleanup=true, bool also_fix_location=true)

Performs WGS specific cleanup.

static bool ParseCodeBreaks(CSeq_feat &feat, CScope &scope)

Parses all valid transl_except Gb-quals into code-breaks for cdregion, then removes the transl_except...

static bool SetMolinfoTech(CBioseq_Handle seq, CMolInfo::ETech tech)

Sets MolInfo::tech for a sequence.

static bool AddLowQualityException(CSeq_entry_Handle entry)

For table2asn -c s Adds an exception of "low-quality sequence region" to coding regions and mRNAs tha...

static bool RemoveUnseenTitles(CSeq_entry_EditHandle::TSeq seq)

Remove all titles in Seqdescr except the last, because it is the only one that would be displayed in ...

static bool RemoveDupBioSource(CSeq_descr &descr)

Remove duplicate biosource descriptors.

static bool ExtendStopPosition(CSeq_feat &f, const CSeq_feat *cdregion, size_t extension=0)

TChanges ExtendedCleanup(CSeq_entry &se, Uint4 options=0)

Cleanup a Seq-entry.

static bool s_IsProductOnFeat(const CSeq_feat &cds)

static bool SetGenePartialByLongestContainedFeature(CSeq_feat &gene, CScope &scope)

Set partialness of gene to match longest feature contained in gene.

static CConstRef< CCode_break > GetCodeBreakForLocation(size_t pos, const CSeq_feat &cds)

utility function for finding the code break for a given amino acid position pos is the position of th...

TChanges BasicCleanup(CSeq_entry &se, Uint4 options=0)

static bool SetCDSPartialsByFrameAndTranslation(CSeq_feat &cds, CScope &scope)

1.

static bool RemoveBadECNumbers(CProt_ref::TEc &ec_num_list)

Delete EC numbers.

static bool AddPartialToProteinTitle(CBioseq_Handle bsh)

Adjusts protein title to reflect partialness.

void SetScope(CScope *scope)

static bool RepairXrefs(const CSeq_feat &f, const CTSE_Handle &tse)

Repairs non-reciprocal xref pairs for specified feature if xrefs between subtypes are permitted and f...

static bool ExtendToStopCodon(CSeq_feat &f, CBioseq_Handle bsh, size_t limit)

Extends a feature up to limit nt to a stop codon, or to the end of the sequence if limit == 0 (partia...

static CRef< CSeq_loc > GetProteinLocationFromNucleotideLocation(const CSeq_loc &nuc_loc, CScope &scope)

static bool ParseCodeBreak(const CSeq_feat &feat, CCdregion &cds, const CTempString &str, CScope &scope, IObjtoolsListener *pMessageListener=nullptr)

Parse string into code break and add to coding region.

static void SetCodeBreakLocation(CCode_break &cb, size_t pos, const CSeq_feat &cds)

utility function for setting code break location given offset pos is the position of the amino acid w...

static bool x_AddLowQualityException(CSeq_feat &feat)

static const string & GetProteinName(const CProt_ref &prot)

static CRef< CBioSource > BioSrcFromFeat(const CSeq_feat &f)

Get BioSource from feature to use for source descriptor.

static bool MergeDupBioSources(CSeq_descr &descr)

static bool SetFrameFromLoc(CCdregion &cdregion, const CSeq_loc &loc, CScope &scope)

Chooses best frame based on location 1.

static bool SetMolinfoBiomol(CBioseq_Handle seq, CMolInfo::EBiomol biomol)

Sets MolInfo::biomol for a sequence.

static bool MoveProteinSpecificFeats(CSeq_entry_Handle seh)

Moves protein-specific features from nucleotide sequences in the Seq-entry to the appropriate protein...

static bool TaxonomyLookup(CSeq_entry_Handle seh)

Looks up Org-refs in the Seq-entry.

static bool PubAlreadyInSet(const CPubdesc &pd, const CSeq_descr &descr)

static bool NormalizeDescriptorOrder(CSeq_descr &descr)

Normalize Descriptor Order on a specific Seq-entry.

static bool ConvertSrcFeatsToSrcDescs(CSeq_entry_Handle seh)

Convert full-length source features to source descriptors.

static bool SetBestFrame(CSeq_feat &cds, CScope &scope)

Translates coding region and selects best frame (without stops, or longest)

static bool x_MergeDupOrgNames(COrgName &on1, const COrgName &add)

static bool FindMatchingLocusGene(CSeq_feat &f, const CGene_ref &gene_xref, CBioseq_Handle bsh)

Detects gene features with matching locus.

static bool MoveFeatToProtein(CSeq_feat_Handle fh)

Moves one feature from nucleotide bioseq to the appropriate protein sequence.

static bool RemoveOrphanLocusGeneXrefs(CSeq_feat &f, CBioseq_Handle bsh)

Removes orphaned locus Gene-xrefs.

static void AddNcbiCleanupObject(int ncbi_cleanup_version, CSeq_descr &descr)

Adds NcbiCleanup User Object to Seq-descr.

static bool AreBioSourcesMergeable(const CBioSource &src1, const CBioSource &src2)

static bool ExpandGeneToIncludeChildren(CSeq_feat &gene, CTSE_Handle &tse)

Expands gene to include features it cross-references.

static vector< CConstRef< CPub > > GetCitationList(CBioseq_Handle bsh)

Get list of pubs that can be used for citations for Seq-feat on a Bioseq-handle.

static bool LocationMayBeExtendedToMatch(const CSeq_loc &orig, const CSeq_loc &improved)

Checks whether it is possible to extend the original location up to improved one.

static bool UpdateECNumbers(CProt_ref::TEc &ec_num_list)

Update EC numbers.

static bool FixRNAEditingCodingRegion(CSeq_feat &cds)

From GB-7563 An action has been requested that will do the following: 1.

static bool x_HasShortIntron(const CSeq_loc &loc, size_t min_len=11)

static bool RemoveNcbiCleanupObject(CSeq_descr &descr)

Removes NcbiCleanup User Objects in the Seq-descr.

static bool SetGeneticCodes(CBioseq_Handle bsh)

Sets genetic codes for coding regions on Bioseq-Handle.

static bool RemoveUnnecessaryGeneXrefs(CSeq_feat &f, CScope &scope)

Removes unnecessary Gene-xrefs.

static bool CleanupCollectionDates(CSeq_entry_Handle seh, bool month_first)

static bool MakeIRDFeatsFromSourceXrefs(CSeq_entry_Handle entry)

From SQD-4329 For each sequence with a source that has an IRD db_xref, create a misc_feature across t...

static bool IsMinPub(const CPubdesc &pd, bool is_refseq_prot)

Is this a "minimal" pub? (If yes, do not rescue from a Seq-feat.cit)

static bool FindMatchingLocus_tagGene(CSeq_feat &f, const CGene_ref &gene_xref, CBioseq_Handle bsh)

Detects gene features with matching locus_tag.

static bool x_MergeDupOrgRefs(COrg_ref &org1, const COrg_ref &add)

static void AutodefId(CSeq_entry_Handle seh)

static bool RemoveNonsuppressingGeneXrefs(CSeq_feat &f)

Removes non-suppressing Gene-xrefs.

static bool RemoveDuplicatePubs(CSeq_descr &descr)

Remove duplicate publications.

static bool IsMethionine(const CCode_break &cb)

static bool SeqLocExtend(CSeq_loc &loc, size_t pos, CScope &scope)

Extends a location to the specificed position.

@Gb_qual.hpp User-defined methods of the data storage class.

static const CTrans_table & GetTransTable(int id)

bool RefersToSameGene(const CGene_ref &xref) const

bool IsSuppressed(void) const

static string GetKey(const COrg_ref &org)

void BasicCleanupBioseqHandle(const CBioseq_Handle &bsh)

void BasicCleanupSeqFeat(CSeq_feat &sf)

void ExtendedCleanup(CSeq_entry_Handle &seh)

void BasicCleanupBioseqSetHandle(CBioseq_set_Handle &bssh)

void SetScope(CScope &scope)

Main methods.

void ExtendedCleanupSeqEntryHandle(CSeq_entry_Handle &seh)

void BasicCleanupSeqEntryHandle(CSeq_entry_Handle &seh)

static bool ShouldRemoveAnnot(const CSeq_annot &annot)

void BasicCleanup(CPubdesc &pd, bool strip_serial)

void BasicCleanupSeqAnnotHandle(CSeq_annot_Handle &sah)

void BasicCleanupSeqFeatHandle(CSeq_feat_Handle &sfh)

@OrgMod.hpp User-defined methods of the data storage class.

bool IsSetOrgMod(void) const

static bool IsECNumberSplit(const string &old_ecno)

static const string & GetECNumberReplacement(const string &old_ecno)

Return a replaced EC number's replacement.

EECNumberStatus

Enzyme Commission number status.

@ eEC_replaced

Obsolete synonym for some other EC number.

@ eEC_unknown

Unrecognized; possibly malformed.

@ eEC_deleted

Withdrawn, with no (single?) replacement.

static EECNumberStatus GetECNumberStatus(const string &ecno)

Determine an EC number's validity and specificity.

@Pubdesc.hpp User-defined methods of the data storage class.

@RNA_ref.hpp User-defined methods of the data storage class.

string GetRnaProductName(void) const

ESubtype GetSubtype(void) const

static bool AllowXref(CSeqFeatData::ESubtype subtype1, CSeqFeatData::ESubtype subtype2)

SeqMap related exceptions.

SeqVector related exceptions.

@Seq_descr.hpp User-defined methods of the data storage class.

const CSeq_descr & GetDescr(void) const

void SetDescr(CSeq_descr &value)

bool IsSetDescr(void) const

CSeq_feat_EditHandle –.

namespace ncbi::objects::

bool HasExceptionText(const string &exception_text) const

Returns whether or not the given exception_text is set for this feature.

bool AddSeqFeatXref(const CSeqFeatXref::TId &id)

Seq-loc iterator class – iterates all intervals from a seq-loc in the correct order.

class CStaticArrayMap<> is an array adaptor that provides an STLish interface to statically-defined a...

TBase::const_iterator const_iterator

static string FixDateFormat(const string &orig_date)

Attempt to fix the format of the date Returns a blank if the format of the date cannot be determined.

CBioseq_Handle GetBioseqHandle(const CSeq_id &id) const

Get Bioseq handle from this TSE.

TSeq_feat_Handles GetFeaturesWithId(CSeqFeatData::E_Choice type, TFeatureIdInt id) const

vector< CSeq_feat_Handle > TSeq_feat_Handles

virtual CRef< CTaxon3_reply > SendOrgRefList(const vector< CRef< COrg_ref > > &list, COrg_ref::fOrgref_parts result_parts=COrg_ref::eOrgref_default, fT3reply_parts t3result_parts=eT3reply_default)

CTempString implements a light-weight string on top of a storage buffer whose lifetime management is ...

char GetCodonResidue(int state) const

static int NextCodonState(int state, unsigned char ch)

EObjectType GetObjectType() const

@ fLabel_Unique

Append a unique tag [V1].

constexpr size_t size() const

const_iterator end() const

const_iterator find(const key_type &key) const

const unsigned int methionine_encoded

void s_GetAuthorsString(string *out_authors, const CAuth_list &auth_list)

SStaticPair< CSeqdesc::E_Choice, int > TSeqdescOrderElem

static CConstRef< CSeq_feat > s_GetCdsByLocation(CScope &scope, const CSeq_loc &feat_loc)

static bool s_NameCloseEnoughC(const CSubSource &s1, const CSubSource &s2)

void RescueProtProductQual(CSeq_feat &feat)

void GetSourceDescriptors(const CSeq_entry &se, vector< const CSeqdesc * > &src_descs)

bool s_IsLocationEndAtOtherLocationInternalEndpoint(const CSeq_loc &loc, const CSeq_loc &other_loc)

DEFINE_STATIC_ARRAY_MAP(TSeqdescOrderMap, sc_SeqdescOrderMap, sc_seqdesc_order_map)

static bool s_SameSubtypeC(const CSubSource &s1, const CSubSource &s2)

static const TRNALengthMap kTrnaLengthMap

static bool s_RemoveTaxnameFromProtRef(const string &taxname, CBioseq_Handle bsh)

string s_KeyFromProcessed(CProt_ref::EProcessed processed)

bool s_SubSourceListUniqued(CBioSource &biosrc)

static CConstRef< CSeqdesc > s_GetTitleDesc(const CSeq_descr &descr)

static int s_SeqDescToOrdering(CSeqdesc::E_Choice chs)

static const string & s_GetProteinNameFromXrefOrQual(const CSeq_feat &cds)

static SIZE_TYPE s_TitleEndsInOrganism(const string &sTitle, const string &sOrganism, SIZE_TYPE &OrganellePos)

bool HasMod(const COrg_ref &org, const string &mod)

static bool s_SubsourceCompareC(const CRef< CSubSource > &st1, const CRef< CSubSource > &st2)

static const TSeqdescOrderElem sc_seqdesc_order_map[]

bool IsSiteRef(const CSeq_feat &sf)

CProt_ref::EProcessed s_ProcessedFromKey(const string &key)

void AddIRDMiscFeature(CBioseq_Handle bh, const CDbtag &tag)

static void s_UpdateTitleString(const CBioSource &src, bool bPartial, string &sTitle)

map< string, TRNALength > TRNALengthMap

static constexpr std::array< string_view, CCleanupChangeCore::eNumberofChangeTypes > sm_ChangeDesc

pair< size_t, bool > TRNALength

CStaticPairArrayMap< CSeqdesc::E_Choice, int > TSeqdescOrderMap

static bool s_IsSwissProt(const CBioseq_Handle &bsh)

static CConstRef< CSeq_feat > s_GetCdsByProduct(CScope &scope, const CSeq_loc &product)

static bool s_RemoveSuffixFromNames(const string &suffix, list< string > &names)

static CRef< CCleanupChange > makeCleanupChange(Uint4 options)

bool s_FirstPubMatchesSecond(const CPubdesc &pd1, const CPubdesc &pd2)

static void s_GetMolInfoAndSrcDescriptors(const CSeq_descr &seq_descr, CConstRef< CSeqdesc > &pMolinfoDesc, CConstRef< CSeqdesc > &pSrcDesc)

const string kLowQualitySequence

bool s_IsPreprotein(CSeq_feat_Handle fh)

static bool s_IsPartial(const CMolInfo &molInfo)

static bool s_SeqDescLessThan(const CRef< CSeqdesc > &desc1, const CRef< CSeqdesc > &desc2)

bool ConvertProteinToImp(CSeq_feat_Handle fh)

bool IsCrossKingdom(const COrg_ref &org, string &first_kingdom, string &second_kingdom)

static bool s_CleanupIsShortrRNA(const CSeq_feat &f, CScope *scope)

static bool s_IsCleanupObject(const CSeqdesc &desc)

CRef< CSeq_loc > ReadLocFromText(const string &text, const CSeq_id *id, CScope *scope)

char x_ValidAminoAcid(string_view abbrev)

bool CleanVisStringJunk(string &str, bool allow_ellipses)

bool Asn2gnbkCompressSpaces(string &val)

weird space compression from C Toolkit

Include a standard set of the NCBI C++ Toolkit most basic headers.

static const char si[8][64]

static const struct name_t names[]

static void DLIST_NAME() append(DLIST_LIST_TYPE *list, DLIST_TYPE *item)

static const char * str(char *buf, int n)

unsigned int TSeqPos

Type for sequence locations and lengths.

constexpr size_t ArraySize(const Element(&)[Size])

#define ITERATE(Type, Var, Cont)

ITERATE macro to sequence through container elements.

#define NON_CONST_ITERATE(Type, Var, Cont)

Non constant version of ITERATE macro.

@ eDiag_Error

Error message.

virtual void Assign(const CSerialObject &source, ESerialRecursionMode how=eRecursive)

Set object to copy of another one.

const TPrim & Get(void) const

virtual bool Equals(const CSerialObject &object, ESerialRecursionMode how=eRecursive) const

Check if both objects contain the same values.

virtual void Assign(const CSerialObject &source, ESerialRecursionMode how=eRecursive)

Optimized implementation of CSerialObject::Assign, which is not so efficient.

void SetPacked_int(TPacked_int &v)

bool IsPartialStart(ESeqLocExtremes ext) const

check start or stop of location for e_Lim fuzz

ENa_strand GetStrand(void) const

Get the location's strand.

virtual void Assign(const CSerialObject &source, ESerialRecursionMode how=eRecursive)

Override Assign() to incorporate cache invalidation.

TSeqPos GetStart(ESeqLocExtremes ext) const

Return start and stop positions of the seq-loc.

bool IsSetStrand(void) const

Get strand.

const CInt_fuzz * GetFuzzFrom(void) const

const CInt_fuzz * GetFuzzTo(void) const

bool IsSetStrand(EIsSetStrand flag=eIsSetStrand_Any) const

Check if strand is set for any/all part(s) of the seq-loc depending on the flag.

bool IsEmpty(void) const

True if the current location is empty.

const CSeq_id * GetId(void) const

Get the id of the location return NULL if has multiple ids or no id at all.

TRange GetRange(void) const

Get the range.

void ResetStrand(void)

Reset the strand on this location.

void SetPartialStart(bool val, ESeqLocExtremes ext)

set / remove e_Lim fuzz on start or stop (lt/gt - indicating partial interval)

ENa_strand GetStrand(void) const

void SetStrand(ENa_strand strand)

Set the strand for all of the location's ranges.

void SetPartialStop(bool val, ESeqLocExtremes ext)

bool IsPartialStop(ESeqLocExtremes ext) const

TSeqPos GetStop(ESeqLocExtremes ext) const

bool RetranslateCDS(const CSeq_feat &cds, CScope &scope)

RetranslateCDS A function to replace the protein Bioseq pointed to by cds.product with the current tr...

bool CopyFeaturePartials(CSeq_feat &dst, const CSeq_feat &src)

CopyFeaturePartials A function to copy the start and end partialness from one feature to another.

void AddProteinFeature(const CBioseq &seq, const string &protein_name, const CSeq_feat &cds, CScope &scope)

AddProteinFeature A function to create a protein feature with the specified protein name.

ELocationInFrame IsLocationInFrame(const CSeq_feat_Handle &cds, const CSeq_loc &loc)

Determines whether location loc is in frame with coding region cds.

bool AdjustFeaturePartialFlagForLocation(CSeq_feat &new_feat)

AdjustFeaturePartialFlagForLocation A function to ensure that Seq-feat.partial is set if either end o...

bool AdjustForCDSPartials(const CSeq_feat &cds, CSeq_entry_Handle seh)

AdjustForCDSPartials A function to make all of the necessary related changes to a Seq-entry after the...

@ eLocationInFrame_InFrame

@ eLocationInFrame_BadStart

@ eLocationInFrame_BadStop

@ eLocationInFrame_BadStartAndStop

TSeqPos GetLength(const CSeq_id &id, CScope *scope)

Get sequence length if scope not null, else return max possible TSeqPos.

TSeqPos LocationOffset(const CSeq_loc &outer, const CSeq_loc &inner, EOffsetType how=eOffset_FromStart, CScope *scope=0)

returns (TSeqPos)-1 if the locations don't overlap

sequence::ECompare Compare(const CSeq_loc &loc1, const CSeq_loc &loc2, CScope *scope)

Returns the sequence::ECompare containment relationship between CSeq_locs.

CRef< CSeq_loc > Seq_loc_Subtract(const CSeq_loc &loc1, const CSeq_loc &loc2, CSeq_loc::TOpFlags flags, CScope *scope)

Subtract the second seq-loc from the first one.

CRef< CSeq_loc > Seq_loc_Merge(const CSeq_loc &loc, CSeq_loc::TOpFlags flags, CScope *scope)

Merge ranges in the seq-loc.

CRef< CSeq_loc > Seq_loc_Add(const CSeq_loc &loc1, const CSeq_loc &loc2, CSeq_loc::TOpFlags flags, CScope *scope)

Add two seq-locs.

@ fCompareOverlapping

Check if seq-locs are overlapping.

@ eOverlap_Contained

2nd contained within 1st extremes

@ eContains

First CSeq_loc contains second.

@ eSame

CSeq_locs contain each other.

@ eContained

First CSeq_loc contained by second.

bool IsPseudo(const CSeq_feat &feat, CScope &scope)

Determines whether given feature is pseudo, using gene associated with feature if necessary Checks to...

static CRef< CBioseq > TranslateToProtein(const CSeq_feat &cds, CScope &scope)

CConstRef< CSeq_feat > GetOverlappingGene(const CSeq_loc &loc, CScope &scope, ETransSplicing eTransSplicing=eTransSplicing_Auto)

CConstRef< CSeq_feat > GetOverlappingCDS(const CSeq_loc &loc, CScope &scope)

static CCdregion::EFrame FindBestFrame(const CSeq_feat &cds, CScope &scope)

Find "best" frame for a coding region.

CConstRef< CSeq_feat > GetmRNAforCDS(const CSeq_feat &cds, CScope &scope)

GetmRNAforCDS A function to find a CSeq_feat representing the appropriate mRNA for a given CDS.

vector< TFeatScore > TFeatScores

void GetOverlappingFeatures(const CSeq_loc &loc, CSeqFeatData::E_Choice feat_type, CSeqFeatData::ESubtype feat_subtype, EOverlapType overlap_type, TFeatScores &feats, CScope &scope, const TBestFeatOpts opts=0, CGetOverlappingFeaturesPlugin *plugin=NULL)

Find all features overlapping the location.

static void Translate(const string &seq, string &prot, const CGenetic_code *code, bool include_stop=true, bool remove_trailing_X=false, bool *alt_start=NULL, bool is_5prime_complete=true, bool is_3prime_complete=true)

Translate a string using a specified genetic code.

CBioseq_Handle GetBioseqHandleFromTSE(const CSeq_id &id, const CTSE_Handle &tse)

Get bioseq handle for sequence withing one TSE.

CRef< CSeq_loc > Map(const CSeq_loc &src_loc)

Map seq-loc.

static CRef< CObjectManager > GetInstance(void)

Return the existing object manager or create one.

CSeq_entry_Handle GetSeq_entryHandle(CDataLoader *loader, const TBlobId &blob_id, EMissing action=eMissing_Default)

Get Seq-entry handle by its blob-id, with possible loading.

CBioseq_Handle GetBioseqHandle(const CSeq_id &id)

Get bioseq handle by seq-id.

CSeq_feat_Handle GetSeq_featHandle(const CSeq_feat &feat, EMissing action=eMissing_Default)

CSeq_annot_Handle GetSeq_annotHandle(const CSeq_annot &annot, EMissing action=eMissing_Default)

void AddScope(CScope &scope, TPriority pri=kPriority_Default)

Add the scope's datasources as a single group with the given priority All data sources (data loaders ...

CSeq_entry_EditHandle GetSeq_entryEditHandle(const CSeq_entry &entry)

@ eLocationToProduct

Map from the feature's location to product.

vector< CSeq_id_Handle > TId

const CSeq_feat::TXref & GetXref(void) const

bool IsSetInst_Mol(void) const

TSeq ConvertSetToSeq(void) const

Do the same as CollapseSet() when sub-entry is of type bioseq.

const CTSE_Handle & GetTSE_Handle(void) const

void SetDescr(TDescr &v) const

CConstRef< CBioseq > GetCompleteBioseq(void) const

Get the complete bioseq.

TClass GetClass(void) const

const CSeq_annot_Handle & GetAnnot(void) const

Get handle to seq-annot for this feature.

bool IsFtable(void) const

CRef< CSeqdesc > RemoveSeqdesc(const CSeqdesc &v) const

CBioseq_set_Handle GetParentBioseq_set(void) const

Return a handle for the parent Bioseq-set, or null handle.

CSeq_entry_Handle GetParentEntry(void) const

Get parent Seq-entry handle.

void SetDescr(TDescr &v) const

TBioseqCore GetBioseqCore(void) const

Get bioseq core structure.

CBioseq_set_EditHandle GetParentBioseq_set(void) const

Get parent bioseq-set edit handle.

void Remove(void) const

Remove current annot.

virtual CConstRef< CSeq_feat > GetSeq_feat(void) const

bool IsSetDescr(void) const

CScope & GetScope(void) const

Get scope this handle belongs to.

const CSeqFeatData & GetData(void) const

TSeqPos GetBioseqLength(void) const

bool AddSeqdesc(CSeqdesc &d) const

CSeq_entry_EditHandle TakeEntry(const CSeq_entry_EditHandle &entry, int index=-1) const

Remove seq-entry from its location and attach to current one.

bool IsSetXref(void) const

CSeq_entry_Handle GetSeq_entry_Handle(void) const

Get parent Seq-entry handle.

TSet ConvertSeqToSet(TClass set_class=CBioseq_set::eClass_not_set) const

Convert the entry from Bioseq to Bioseq-set.

void Remove(void) const

Remove the feature from Seq-annot.

const CTSE_Handle & GetTSE_Handle(void) const

CConstRef< CSeq_annot > GetCompleteSeq_annot(void) const

Complete and return const reference to the current seq-annot.

TInst_Mol GetInst_Mol(void) const

CSeq_feat_EditHandle AddFeat(const CSeq_feat &new_obj) const

CConstRef< CBioseq_set > GetCompleteBioseq_set(void) const

Return the complete bioseq-set object.

virtual const CSeq_loc & GetProduct(void) const

bool IsSetProduct(void) const

bool HasAnnots(void) const

CConstRef< CSeq_id > GetSeqId(void) const

Get id which can be used to access this bioseq handle Throws an exception if none is available.

virtual const CSeq_loc & GetLocation(void) const

void SetInst(TInst &v) const

void Remove(ERemoveMode mode=eRemoveSeq_entry) const

CRef< CSeqdesc > ReplaceSeqdesc(const CSeqdesc &old_desc, CSeqdesc &new_desc) const

CBioseq_Handle GetBioseqHandle(const CSeq_id &id) const

Get Bioseq handle from the TSE of this Seq-entry.

CSeq_annot_EditHandle AttachAnnot(CSeq_annot &annot) const

Attach an annotation.

CSeq_entry_EditHandle GetEditHandle(void) const

Get 'edit' version of handle.

CSeq_entry_Handle GetTopLevelEntry(void) const

Get top level Seq-entry handle.

const TDescr & GetDescr(void) const

CBioseq_EditHandle GetEditHandle(void) const

Get 'edit' version of handle.

CSeq_entry_Handle GetParentEntry(void) const

Return a handle for the parent seq-entry of the bioseq.

TInst_Length GetInst_Length(void) const

bool IsSetInst(void) const

bool IsSetClass(void) const

bool AddSeqdesc(CSeqdesc &d) const

CSeq_annot_EditHandle GetEditHandle(void) const

Get 'edit' version of handle.

const TDescr & GetDescr(void) const

CConstRef< CSeq_entry > GetCompleteSeq_entry(void) const

Complete and get const reference to the seq-entry.

CScope & GetScope(void) const

Get scope this handle belongs to.

CRef< CSeqdesc > RemoveSeqdesc(const CSeqdesc &d) const

CScope & GetScope(void) const

Get scope this handle belongs to.

CScope & GetScope(void) const

Get scope this handle belongs to.

CSeq_feat_EditHandle TakeFeat(const CSeq_feat_EditHandle &handle) const

CSeq_annot_EditHandle GetAnnot(void) const

CConstRef< CSeq_feat > GetOriginalSeq_feat(void) const

CSeq_entry_EditHandle AttachEntry(CSeq_entry &entry, int index=-1) const

Attach an existing seq-entry.

CScope & GetScope(void) const

Get scope this handle belongs to.

bool IsSetDescr(void) const

const CGene_ref * GetGeneXref(void) const

get gene (if present) from Seq-feat.xref list

void Replace(const CSeq_feat &new_feat) const

Replace the feature with new Seq-feat object.

bool AddSeqdesc(CSeqdesc &v) const

const TId & GetId(void) const

bool IsSetData(void) const

const TInst & GetInst(void) const

@ eCoding_Iupac

Set coding to printable coding (Iupacna or Iupacaa)

SAnnotSelector & SetFeatType(TFeatType type)

Set feature type (also set annotation type to feat)

const CSeq_loc & GetLocation(void) const

const CSeq_feat & GetOriginalFeature(void) const

Get original feature with unmapped location/product.

const CSeq_feat_Handle & GetSeq_feat_Handle(void) const

Get original feature handle.

SAnnotSelector & IncludeFeatType(TFeatType type)

Include feature type in the search.

CConstRef< CSeq_feat > GetSeq_feat(void) const

Get current seq-feat.

@ fIncludeGivenEntry

Include the top (given) entry.

@ fRecursive

Iterate recursively.

const_iterator begin(void) const

TObjectType * GetPointer(void) const THROWS_NONE

Get pointer,.

CConstRef< C > ConstRef(const C *object)

Template function for conversion of const object pointer to CConstRef.

CRef< C > Ref(C *object)

Helper functions to get CRef<> and CConstRef<> objects.

void Reset(void)

Reset reference object.

void Reset(void)

Reset reference object.

bool Empty(void) const THROWS_NONE

Check if CRef is empty – not pointing to any object, which means having a null value.

uint32_t Uint4

4-byte (32-bit) unsigned integer

#define END_NCBI_SCOPE

End previously defined NCBI scope.

#define END_SCOPE(ns)

End the previously defined scope.

#define BEGIN_NCBI_SCOPE

Define ncbi namespace.

#define BEGIN_SCOPE(ns)

Define a new scope.

void AddWord(const string &word, const MatchType &match)

int GetNextState(int state, char letter) const

const vector< MatchType > & GetMatches(int state) const

bool IsMatchFound(int state) const

bool IsPrimed(void) const

int GetInitialState(void) const

NCBI_NS_STD::string::size_type SIZE_TYPE

static CTempString TruncateSpaces_Unsafe(const CTempString str, ETrunc where=eTrunc_Both)

Truncate whitespace in a string.

static int CompareNocase(const CTempString s1, SIZE_TYPE pos, SIZE_TYPE n, const char *s2)

Case-insensitive compare of a substring with another string.

static SIZE_TYPE FindNoCase(const CTempString str, const CTempString pattern, SIZE_TYPE start, SIZE_TYPE end, EOccurrence which=eFirst)

Find the pattern in the specified range of a string using a case insensitive search.

static bool EndsWith(const CTempString str, const CTempString end, ECase use_case=eCase)

Check if a string ends with a specified suffix value.

static bool IsBlank(const CTempString str, SIZE_TYPE pos=0)

Check if a string is blank (has no text).

static void TruncateSpacesInPlace(string &str, ETrunc where=eTrunc_Both)

Truncate whitespace in a string (in-place)

static SIZE_TYPE Find(const CTempString str, const CTempString pattern, ECase use_case=eCase, EDirection direction=eForwardSearch, SIZE_TYPE occurrence=0)

Find the pattern in the string.

static string Join(const TContainer &arr, const CTempString &delim)

Join strings using the specified delimiter.

static bool StartsWith(const CTempString str, const CTempString start, ECase use_case=eCase)

Check if a string starts with a specified prefix value.

static bool EqualNocase(const CTempString s1, SIZE_TYPE pos, SIZE_TYPE n, const char *s2)

Case-insensitive equality of a substring with another string.

static bool Equal(const CTempString s1, SIZE_TYPE pos, SIZE_TYPE n, const char *s2, ECase use_case=eCase)

Test for equality of a substring with another string.

@ eReverseSearch

Search in a backward direction.

@ eNocase

Case insensitive compare.

static const char label[]

void SetSerial_number(TSerial_number value)

Assign a value to Serial_number data member.

list< CRef< CAuthor > > TStd

list< CRef< CArticleId > > Tdata

bool IsSetNames(void) const

Check if a value has been assigned to Names data member.

void SetCit(const TCit &value)

Assign a value to Cit data member.

const TStr & GetStr(void) const

Get the variant data.

bool IsStr(void) const

Check if variant Str is selected.

const TNames & GetNames(void) const

Get the Names member data.

bool IsMl(void) const

Check if variant Ml is selected.

const TStd & GetStd(void) const

Get the variant data.

const TMl & GetMl(void) const

Get the variant data.

bool IsStd(void) const

Check if variant Std is selected.

const TSubtype & GetSubtype(void) const

Get the Subtype member data.

TGenome GetGenome(void) const

Get the Genome member data.

TOrigin GetOrigin(void) const

Get the Origin member data.

void SetSubtype(TSubtype value)

Assign a value to Subtype data member.

bool IsSetOrg(void) const

Check if a value has been assigned to Org data member.

list< CRef< CSubSource > > TSubtype

bool IsSetSubtype(void) const

Check if a value has been assigned to Subtype data member.

void SetIs_focus(void)

Set NULL data member (assign 'NULL' value to Is_focus data member).

void SetOrigin(TOrigin value)

Assign a value to Origin data member.

const TOrg & GetOrg(void) const

Get the Org member data.

bool IsSetOrigin(void) const

Check if a value has been assigned to Origin data member.

void SetGenome(TGenome value)

Assign a value to Genome data member.

TSubtype GetSubtype(void) const

Get the Subtype member data.

bool IsSetGenome(void) const

Check if a value has been assigned to Genome data member.

bool IsSetSubtype(void) const

Check if a value has been assigned to Subtype data member.

void SetOrg(TOrg &value)

Assign a value to Org data member.

void SetName(const TName &value)

Assign a value to Name data member.

const TName & GetName(void) const

Get the Name member data.

bool IsSetIs_focus(void) const

to distinguish biological focus Check if a value has been assigned to Is_focus data member.

EGenome

biological context

bool IsSetName(void) const

Check if a value has been assigned to Name data member.

TSubtype & SetSubtype(void)

Assign a value to Subtype data member.

@ eSubtype_collection_date

DD-MMM-YYYY format.

TTo GetTo(void) const

Get the To member data.

TFrom GetFrom(void) const

Get the From member data.

bool IsSetLocus_tag(void) const

systematic gene name (e.g., MI0001, ORF0069) Check if a value has been assigned to Locus_tag data mem...

bool IsSetLocus(void) const

Official gene symbol Check if a value has been assigned to Locus data member.

const TLocus_tag & GetLocus_tag(void) const

Get the Locus_tag member data.

const TLocus & GetLocus(void) const

Get the Locus member data.

TId GetId(void) const

Get the variant data.

const TMod & GetMod(void) const

Get the Mod member data.

bool IsSetDb(void) const

ids in taxonomic or culture dbases Check if a value has been assigned to Db data member.

const TLineage & GetLineage(void) const

Get the Lineage member data.

const TDiv & GetDiv(void) const

Get the Div member data.

TFixed_level GetFixed_level(void) const

Get the Fixed_level member data.

TMgcode GetMgcode(void) const

Get the Mgcode member data.

TGcode GetGcode(void) const

Get the Gcode member data.

TDb & SetDb(void)

Assign a value to Db data member.

bool IsSetFixed_level(void) const

Check if a value has been assigned to Fixed_level data member.

bool IsSetLineage(void) const

lineage with semicolon separators Check if a value has been assigned to Lineage data member.

vector< CRef< CDbtag > > TDb

bool IsSetMod(void) const

unstructured modifiers Check if a value has been assigned to Mod data member.

bool IsPartial(void) const

Check if variant Partial is selected.

void SetDiv(const TDiv &value)

Assign a value to Div data member.

TSyn & SetSyn(void)

Assign a value to Syn data member.

const TName & GetName(void) const

Get the Name member data.

const TTaxname & GetTaxname(void) const

Get the Taxname member data.

bool IsSetMgcode(void) const

mitochondrial genetic code Check if a value has been assigned to Mgcode data member.

const TLevel & GetLevel(void) const

Get the Level member data.

bool IsSetName(void) const

Check if a value has been assigned to Name data member.

const TBinomial & GetBinomial(void) const

Get the variant data.

const TDb & GetDb(void) const

Get the Db member data.

const TSyn & GetSyn(void) const

Get the Syn member data.

bool IsSetDiv(void) const

GenBank division code Check if a value has been assigned to Div data member.

bool IsSetMod(void) const

Check if a value has been assigned to Mod data member.

const Tdata & Get(void) const

Get the member data.

const TName & GetName(void) const

Get the Name member data.

list< CRef< COrgMod > > TMod

void SetGcode(TGcode value)

Assign a value to Gcode data member.

bool IsSetGenus(void) const

required Check if a value has been assigned to Genus data member.

void SetMgcode(TMgcode value)

Assign a value to Mgcode data member.

const TSpecies & GetSpecies(void) const

Get the Species member data.

list< CRef< CTaxElement > > Tdata

void ResetDb(void)

Reset Db data member.

bool IsSetOrgname(void) const

Check if a value has been assigned to Orgname data member.

bool IsSetTaxname(void) const

preferred formal name Check if a value has been assigned to Taxname data member.

bool IsSetLevel(void) const

Check if a value has been assigned to Level data member.

TMod & SetMod(void)

Assign a value to Mod data member.

bool IsSetGcode(void) const

genetic code (see CdRegion) Check if a value has been assigned to Gcode data member.

TMod & SetMod(void)

Assign a value to Mod data member.

void SetOrgname(TOrgname &value)

Assign a value to Orgname data member.

const TGenus & GetGenus(void) const

Get the Genus member data.

const TPartial & GetPartial(void) const

Get the variant data.

bool IsSet(void) const

Check if a value has been assigned to data member.

const TMod & GetMod(void) const

Get the Mod member data.

bool IsSetSyn(void) const

synonyms for taxname or common Check if a value has been assigned to Syn data member.

bool IsSetSpecies(void) const

species required if subspecies used Check if a value has been assigned to Species data member.

bool IsSetName(void) const

Check if a value has been assigned to Name data member.

void SetLineage(const TLineage &value)

Assign a value to Lineage data member.

const TOrgname & GetOrgname(void) const

Get the Orgname member data.

bool IsBinomial(void) const

Check if variant Binomial is selected.

EProcessed

processing status

const TName & GetName(void) const

Get the Name member data.

TProcessed GetProcessed(void) const

Get the Processed member data.

bool IsSetProcessed(void) const

Check if a value has been assigned to Processed data member.

bool IsSetName(void) const

protein name Check if a value has been assigned to Name data member.

const TEc & GetEc(void) const

Get the Ec member data.

TName & SetName(void)

Assign a value to Name data member.

@ eProcessed_signal_peptide

@ eProcessed_transit_peptide

TPmid & SetPmid(void)

Select the variant.

list< CRef< CPub > > Tdata

TMuid & SetMuid(void)

Select the variant.

const Tdata & Get(void) const

Get the member data.

list< CRef< CPub > > TPub

TGen & SetGen(void)

Select the variant.

bool IsSetExt(void) const

generic fields for ncRNA, tmRNA, miscRNA Check if a value has been assigned to Ext data member.

void SetAa(TAa &value)

Assign a value to Aa data member.

const TVal & GetVal(void) const

Get the Val member data.

TXref & SetXref(void)

Assign a value to Xref data member.

void SetQual(const TQual &value)

Assign a value to Qual data member.

const TKey & GetKey(void) const

Get the Key member data.

bool IsSetComment(void) const

Check if a value has been assigned to Comment data member.

vector< CRef< CDbtag > > TDbxref

const TPub & GetPub(void) const

Get the variant data.

bool IsSetData(void) const

the specific data Check if a value has been assigned to Data data member.

bool IsSetQual(void) const

qualifiers Check if a value has been assigned to Qual data member.

E_Choice Which(void) const

Which variant is currently selected.

bool IsSetCode(void) const

genetic code used Check if a value has been assigned to Code data member.

bool IsProt(void) const

Check if variant Prot is selected.

TNcbi8aa GetNcbi8aa(void) const

Get the variant data.

E_Choice Which(void) const

Which variant is currently selected.

void SetLocation(TLocation &value)

Assign a value to Location data member.

bool IsCdregion(void) const

Check if variant Cdregion is selected.

bool IsImp(void) const

Check if variant Imp is selected.

void ResetCode(void)

Reset Code data member.

void SetComment(const TComment &value)

Assign a value to Comment data member.

void SetProduct(TProduct &value)

Assign a value to Product data member.

const TQual & GetQual(void) const

Get the Qual member data.

bool IsSetKey(void) const

Check if a value has been assigned to Key data member.

const TId & GetId(void) const

Get the Id member data.

void SetCode(TCode &value)

Assign a value to Code data member.

bool IsSetXref(void) const

cite other relevant features Check if a value has been assigned to Xref data member.

const TLocation & GetLocation(void) const

Get the Location member data.

void SetExcept(TExcept value)

Assign a value to Except data member.

bool IsLocal(void) const

Check if variant Local is selected.

void ResetLoc(void)

Reset Loc data member.

bool IsGene(void) const

Check if variant Gene is selected.

list< CRef< CCode_break > > TCode_break

TFrame GetFrame(void) const

Get the Frame member data.

const TData & GetData(void) const

Get the Data member data.

bool IsSetExcept(void) const

something funny about this? Check if a value has been assigned to Except data member.

const TExcept_text & GetExcept_text(void) const

Get the Except_text member data.

bool IsSetExcept_text(void) const

explain if except=TRUE Check if a value has been assigned to Except_text data member.

const TCode & GetCode(void) const

Get the Code member data.

void SetData(TData &value)

Assign a value to Data data member.

TCode_break & SetCode_break(void)

Assign a value to Code_break data member.

void ResetComment(void)

Reset Comment data member.

const TCdregion & GetCdregion(void) const

Get the variant data.

bool IsSetAa(void) const

Check if a value has been assigned to Aa data member.

const TBiosrc & GetBiosrc(void) const

Get the variant data.

bool IsSetId(void) const

Check if a value has been assigned to Id data member.

const TAa & GetAa(void) const

Get the Aa member data.

void SetLoc(TLoc &value)

Assign a value to Loc data member.

const TProduct & GetProduct(void) const

Get the Product member data.

bool IsSetQual(void) const

Check if a value has been assigned to Qual data member.

TNcbieaa GetNcbieaa(void) const

Get the variant data.

const TComment & GetComment(void) const

Get the Comment member data.

void SetVal(const TVal &value)

Assign a value to Val data member.

const TGene & GetGene(void) const

Get the variant data.

void SetExcept_text(const TExcept_text &value)

Assign a value to Except_text data member.

const TProt & GetProt(void) const

Get the variant data.

void ResetLocation(void)

Reset Location data member.

TExcept GetExcept(void) const

Get the Except member data.

const TXref & GetXref(void) const

Get the Xref member data.

TNcbieaa & SetNcbieaa(void)

Select the variant.

vector< CRef< CSeqFeatXref > > TXref

void ResetProduct(void)

Reset Product data member.

const TQual & GetQual(void) const

Get the Qual member data.

const TRna & GetRna(void) const

Get the variant data.

TNcbistdaa GetNcbistdaa(void) const

Get the variant data.

TQual & SetQual(void)

Assign a value to Qual data member.

const TCode_break & GetCode_break(void) const

Get the Code_break member data.

bool IsSetProduct(void) const

product of process Check if a value has been assigned to Product data member.

bool IsRna(void) const

Check if variant Rna is selected.

void SetFrame(TFrame value)

Assign a value to Frame data member.

void ResetQual(void)

Reset Qual data member.

bool IsSetCode_break(void) const

individual exceptions Check if a value has been assigned to Code_break data member.

const TImp & GetImp(void) const

Get the variant data.

bool IsSetFrame(void) const

Check if a value has been assigned to Frame data member.

bool IsSetLocation(void) const

feature made from Check if a value has been assigned to Location data member.

@ e_not_set

No variant selected.

@ e_Pub

publication applies to this seq

@ eFrame_not_set

not set, code uses one

@ eFrame_three

reading frame

@ e_Ncbi8aa

NCBI8aa code.

@ e_Ncbieaa

ASCII value of NCBIeaa code.

bool IsMix(void) const

Check if variant Mix is selected.

list< CRef< CSeq_interval > > Tdata

ENa_strand

strand of nucleic acid

const Tdata & Get(void) const

Get the member data.

Tdata & Set(void)

Assign a value to data member.

const TWhole & GetWhole(void) const

Get the variant data.

list< CRef< CSeq_loc > > Tdata

E_Choice Which(void) const

Which variant is currently selected.

E_Choice Which(void) const

Which variant is currently selected.

bool IsPacked_int(void) const

Check if variant Packed_int is selected.

Tdata & Set(void)

Assign a value to data member.

bool IsWhole(void) const

Check if variant Whole is selected.

bool IsInt(void) const

Check if variant Int is selected.

bool IsPnt(void) const

Check if variant Pnt is selected.

const TPacked_int & GetPacked_int(void) const

Get the variant data.

TSet & SetSet(void)

Select the variant.

const TSet & GetSet(void) const

Get the variant data.

bool IsSeq(void) const

Check if variant Seq is selected.

bool IsSetSeq_set(void) const

Check if a value has been assigned to Seq_set data member.

list< CRef< CSeq_annot > > TAnnot

bool IsSet(void) const

Check if variant Set is selected.

const TSeq_set & GetSeq_set(void) const

Get the Seq_set member data.

void ResetDescr(void)

Reset Descr data member.

list< CRef< CSeq_entry > > TSeq_set

TSeq & SetSeq(void)

Select the variant.

TSeq_set & SetSeq_set(void)

Assign a value to Seq_set data member.

@ eClass_pop_set

population study

@ eClass_phy_set

phylogenetic study

@ eClass_wgs_set

whole genome shotgun project

@ eClass_mut_set

set of mutations

@ eClass_eco_set

ecological sample study

@ eClass_nuc_prot

nuc acid and coded proteins

@ eClass_gen_prod_set

genomic products, chrom+mRNA+protein

@ eClass_genbank

converted genbank

@ eClass_small_genome_set

viral segments or mitochondrial minicircles

const TIupacaa & GetIupacaa(void) const

Get the variant data.

bool IsSetComment(void) const

any comment on this pub in context Check if a value has been assigned to Comment data member.

bool IsSetCompleteness(void) const

Check if a value has been assigned to Completeness data member.

list< CRef< CSeqdesc > > Tdata

TId & SetId(void)

Assign a value to Id data member.

const TUser & GetUser(void) const

Get the variant data.

void ResetDescr(void)

Reset Descr data member.

bool IsSetSeq_data(void) const

the sequence Check if a value has been assigned to Seq_data data member.

void SetPub(TPub &value)

Assign a value to Pub data member.

const TInst & GetInst(void) const

Get the Inst member data.

TTitle & SetTitle(void)

Select the variant.

TPub & SetPub(void)

Select the variant.

bool IsIupacaa(void) const

Check if variant Iupacaa is selected.

const TComment & GetComment(void) const

Get the Comment member data.

bool IsSetAnnot(void) const

Check if a value has been assigned to Annot data member.

bool IsSetMol(void) const

Check if a value has been assigned to Mol data member.

const TTitle & GetTitle(void) const

Get the variant data.

const TSource & GetSource(void) const

Get the variant data.

const TPub & GetPub(void) const

Get the variant data.

bool IsSetFig(void) const

figure in paper Check if a value has been assigned to Fig data member.

const TAnnot & GetAnnot(void) const

Get the Annot member data.

const TId & GetId(void) const

Get the Id member data.

void SetReftype(TReftype value)

Assign a value to Reftype data member.

TTech GetTech(void) const

Get the Tech member data.

const Tdata & Get(void) const

Get the member data.

bool IsSetInst(void) const

the sequence data Check if a value has been assigned to Inst data member.

bool IsSetName(void) const

name used in paper Check if a value has been assigned to Name data member.

list< CRef< CSeq_id > > TId

TMol GetMol(void) const

Get the Mol member data.

TSource & SetSource(void)

Select the variant.

bool IsSetDescr(void) const

descriptors Check if a value has been assigned to Descr data member.

E_Choice

Choice variants.

bool IsSet(void) const

Check if a value has been assigned to data member.

TBiomol GetBiomol(void) const

Get the Biomol member data.

void SetBiomol(TBiomol value)

Assign a value to Biomol data member.

EMol

molecule class in living organism

void SetDescr(TDescr &value)

Assign a value to Descr data member.

bool IsSetTech(void) const

Check if a value has been assigned to Tech data member.

bool IsSetPub(void) const

the citation(s) Check if a value has been assigned to Pub data member.

TUser & SetUser(void)

Select the variant.

bool IsSetNum(void) const

numbering from paper Check if a value has been assigned to Num data member.

TCompleteness GetCompleteness(void) const

Get the Completeness member data.

list< CRef< CSeq_feat > > TFtable

E_Choice Which(void) const

Which variant is currently selected.

void SetComment(const TComment &value)

Assign a value to Comment data member.

Tdata & Set(void)

Assign a value to data member.

list< CRef< CSeq_annot > > TAnnot

void SetSeq_data(TSeq_data &value)

Assign a value to Seq_data data member.

const TPub & GetPub(void) const

Get the Pub member data.

const TSeq_data & GetSeq_data(void) const

Get the Seq_data member data.

void SetTech(TTech value)

Assign a value to Tech data member.

const TMolinfo & GetMolinfo(void) const

Get the variant data.

TMolinfo & SetMolinfo(void)

Select the variant.

bool IsUser(void) const

Check if variant User is selected.

@ eReftype_sites

refers to unspecified features

@ eReftype_feats

refers to specified features

@ eTech_concept_trans

conceptual translation

@ eTech_standard

standard sequencing

@ e_Embl

EMBL specific information.

@ e_Het

cofactor, etc associated but not bound

@ e_Org

if all from one organism

@ e_Num

a numbering system

@ e_User

user defined object

@ e_Update_date

date of last update

@ e_Pub

a reference to the publication

@ e_Pir

PIR specific info.

@ e_Genbank

GenBank specific info.

@ e_Prf

PRF specific information.

@ e_Mol_type

type of molecule

@ e_Sp

SWISSPROT specific info.

@ e_Dbxref

xref to other databases

@ e_Comment

a more extensive comment

@ e_Method

sequencing method

@ e_Modelev

model evidence for XM records

@ e_Region

overall region (globin locus)

@ e_Molinfo

info on the molecule and techniques

@ e_Maploc

map location of this sequence

@ e_Create_date

date entry first created/released

@ e_Title

a title for this sequence

@ e_Pdb

PDB specific information.

@ e_Name

a name for this sequence

@ e_Source

source of materials, includes Org-ref

@ eMol_na

just a nucleic acid

where boath are integers</td > n< td ></td > n</tr > n< tr > n< td > tse</td > n< td > optional</td > n< td > String</td > n< td class=\"description\"> TSE option controls what blob is orig

const struct ncbi::grid::netcache::search::fields::KEY key

const CharType(& source)[N]

static unsigned int ud(time_t one, time_t two)

double r(size_t dimension_, const Int4 *score_, const double *prob_, double theta_)

void copy(Njn::Matrix< S > *matrix_, const Njn::Matrix< T > &matrix0_)

static int match(PCRE2_SPTR start_eptr, PCRE2_SPTR start_ecode, uint16_t top_bracket, PCRE2_SIZE frame_size, pcre2_match_data *match_data, match_block *mb)

#define FOR_EACH_PUB_ON_PUBDESC(Itr, Var)

FOR_EACH_PUB_ON_PUBDESC EDIT_EACH_PUB_ON_PUBDESC.

CSubSource::TSubtype TSUBSOURCE_SUBTYPE

#define SUBSOURCE_ON_BIOSOURCE_IS_SORTED(Var, Func)

SUBSOURCE_ON_BIOSOURCE_IS_SORTED.

#define SORT_SUBSOURCE_ON_BIOSOURCE(Var, Func)

SORT_SUBSOURCE_ON_BIOSOURCE.

#define NCBI_SEQID(Type)

@NAME Convenience macros for NCBI objects

Utility macros and typedefs for exploring NCBI objects from seqset.asn.

#define RESET_FIELD(Var, Fld)

RESET_FIELD base macro.

#define FIELD_IS_SET(Var, Fld)

FIELD_IS_SET base macro.

#define GET_FIELD(Var, Fld)

GET_FIELD base macro.

bool seq_mac_is_sorted(Iter first, Iter last, Comp comp)

#define BEGIN_COMMA_END(container)

static SLJIT_INLINE sljit_ins msg(sljit_gpr r, sljit_s32 d, sljit_gpr x, sljit_gpr b)

Template structure SStaticPair is simlified replacement of STL pair<> Main reason of introducing this...

int g(Seg_Gsm *spe, Seq_Mtf *psm, Thd_Gsm *tdg)


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