Inbred Strains of Mice: SWXL
SWXL-Inbr. ?. Set of 7 recombinant inbred strains maintained at the Jackson Laboratory.
SWXL-4 mice exhibit tonic-clonic and generalised seizures similar to the commonest epilepsy in humans. Seizures are observed in routine handling from about 80 days of age, and are due to a dominant gene Szf1 on chromosome 7 which accounts for about 32% of the variation in susceptibility (Frankel et al, 1994).
Frankel W. N., Taylor B. A., Noebels J. L., and Lutz C. M. (1994) Genetic epilepsy model derived from common inbred mouse strains. Genetics 138, 481-489. INBRED STRAINS OF MICERetroSearch is an open source project built by @garambo | Open a GitHub Issue
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