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MGI - Inbred Strains: SHM

Inbred Strains of Mice: SHM

SHM/2Gn

Inbr: 35. Genet: +

/shm.

Origin:

shm

(shambling) mutation arose in random-bred stock in March 1960. This strain descended from (SHM/Gn x C57BL/6J) x C3HeB/FeJ (SHM/Gn discontinued at F35 in 1970).

Characteristics

Homozygotes have abnormal gait, small body size, phospholipidosis, sterility, low viability (

Green, 1967

).

Green E. L. (1967) Shambling, a neurological mutant of the mouse. J. Hered. 58, 65-68. INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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