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MGI - Inbred Strains: SEC

Inbred Strains of Mice: SEC

Pale brown:

Origin: Green prior to 1946 from a cross between NB and BALB/c. Carries

(short-ear) gene causing short ears and skeletal abnormalities. Substrains as follows:

Inbr (Rl) 100 +. Colour ?:

.Origin: E.L.Green 1948 to Rl at F20-F21. Maint. by J.

Inbr (Le) 149. Gets multiple lung cysts, especially in

.

Inbr (J) 138. From SEC/1Gn, but short-ear eliminated by E.S.Russell.

High shuttle-box avoidance (2/5) (

., 1972). High plasma cholinesterase activity (7/22 in females, 2/22 in males) (

., 1967). High hepatic delta-aminolaevulinic acid synthetase activity after DDC treatment (3/15) (

). Low sensitivity of females to X-irradiation (5/5) (

). Low lymphocyte phytohaemagglutinin response (31/43) (

., 1975). Good reproductive performance (1/5) (

).

Ehling U. H. (1964) Strain variation in reproductive capacity and radiation response of female mice. Radiation Res. 23, 603-610.

Gross S. and Hutton J. (1971) Induction of hepatic -aminolaevulinic acid synthetase activity in strains of inbred mice. J. Biol. Chem. 246, 606-614.

Heiniger H. J., Taylor B. A., Hards E. J., and Meier H. (1975) Heritability of the phytohaemagglutinin responsiveness of lymphocytes and its relationship to leukemogenesis. Cancer Res. 35, 825-831.

Messeri P., Oliverio A., and Bovet D. (1972) Relations between avoidance and activity. A diallel study in mice. Behav. Biol. 7, 733-742.

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