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MGI - Inbred Strains: KE

Inbred Strains of Mice: KE

Inbr:F94 (Kw). Genet:

Origin: Krzanowska 1952, from mice of unknown origin; cross also produced KP.

Mean litter size 6.1; low percentage of fertilised ova. 17.6% of spermatozoa have abnormal heads, the inheritance of this character being connected to the Y chromosome and may be due to a rel. deficiency of androgens (

). Sperm head shape, the level of sperm abnormalities and fertilizing capacity are determined largely autonomously by genes acting in the germ cells. (

).

Krzanowska H., Wabik-Sliz B., and Rafinski J. (1991) Phenotype and fertilizing capacity of spermatozoa of chimaeric mice produced from two strains that differ in sperm quality. J. Reprod. Fertil. 91, 667-676.

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