Inbred Strains of Mice: ICGN
ICGNInbr. F26 (Asano, 1993). Albino. Origin: Outbred ICR stock inbred by Ogura,Takano, Yamamoto and Asano, Dept. of Veterinary Sci. NIH, Japan. All animals develop glomerular nephritis (
Ogura et al 1989, 1990, 1991a,b). Initially, mice develop hyproteinemia and hypoalbuminemia with a progressive rise in urinary protein. Later the concentrations of total cholesterol, triglyceride and betalipoprotein increase. Finally there is a rapid deterioration of renal function with high blood urea nitrogen and creatinine levels (
Ogura et al, 1994).
Ogura A., Asano T., Matuda J., Nakagawa M., and Fukui M. (1989) Characteristics of mutant mice (ICGN) with spontaneous renal lesions: a new model for human nephrotic syndrome. Lab. Anim. 23, 169-174. INBRED STRAINS OF MICERetroSearch is an open source project built by @garambo | Open a GitHub Issue
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