Inbred Strains of Mice: HLG
HLGInbr. >30 (1993). Albino,
A,B,c,D.An inbred strain in 1938 at the Inst. of Radiology, Univ. of Freiburg. To Heiligernberg in 1945, then returned to Freiburg in 1950. In 1982 to Inst. of Radiation Biology, University Clinic Essen, Germany. Brother x sister mating started in 1985 by Dr. D. Buttner. Defined at 22 biochemical loci. High fat content, especially in older females. Good breeding performance. Used because of its synchrony in early embryonal development (
Molls et al 1983). High incidence of spontaneous and radiation-induced congenital malformations (
Pampfer and Streffer 1988). High incidence of gastroschisis, a herniation of the abdominal viscera with umbilical ring disruption and intestinal evisceration following X-ray exposure of the zygotes (
Hillebrandt et al, 1996).
Hillebrandt S., Streffer C., and Muller W. U. (1996) Genetic analysis of the cause of gastroschisis in the HLG mouse strain. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis 372, 43-51. INBRED STRAINS OF MICERetroSearch is an open source project built by @garambo | Open a GitHub Issue
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