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Showing content from http://www.informatics.jax.org/external/festing/mouse/docs/../docs/GT.shtml below:

MGI - Inbred Strains: GT

Inbred Strains of Mice: GT

GT

Inbr (Le) 28. Breeders are agouti:

A,gt/+;gt/gt

are light grey with white belly spot and have tremors like myelin deficient mice. Origin: Developed by Lane.

gt

mutation arose in strain HYIII/Le in 1977 at F55. One outcross to C3HeB/FeJ x C57BL/6-

AwJ

F1, then bxs. Has a spontaneous spongiform encephalopathy whose expression is determined by the interaction of genetic factors and an unconventional unrecognised transmissible agent (

Sidman et al 1985

). The strain is maintained only as frozen embryos by Dr. T Cunliffe-Beamer.

Sidman R. L., Kinney H. C., and Sweet H. O. (1985) Transmissable spongiform encephalopathy in the gray tremor mutant mouse. Proc. Natl. Acad. Sci. USA 82, 253-257. INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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