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MGI - Inbred Strains: BOB

Inbred Strains of Mice: BOB

BOB

Inbr: F92. Albino. Genet:

a, c, rd.

Strain developed after 1945 from random-bred mice of unknown origin at Brown University.

Characteristics

Small spinal cord (22/25) (

Roderick et al., 1973

., 1973). High lymphocyte phytohaemagglutinin response (6/43) (

Heiniger et al., 1975

., 1975). Develops leukaemia on infection by Friend virus (cf. 5/11) (

Dietz and Rich, 1972

).

Dietz M. and Rick M. A. (1972) Effect of host strain and H-2 type on spontaneous regression of murine leukemia virus. Int. J. Cancer 10, 99-104.

Heiniger H. J., Taylor B. A., Hards E. J., and Meier H. (1975) Heritability of the phytohaemagglutinin responsiveness of lymphocytes and its relationship to leukemogenesis. Cancer Res. 35, 825-831.

Roderick T. H., Wimer R. E., Wimer C. C., and Schwartzkroin P. A. (1973) Genetic and phenotypic variation in weight of brain and spinal cord between inbred strains of mice. Brain Res. 64, 345-353.

INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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