Inbred Strains of Mice: AU
AUInbr: F? + 35. Genet:
a, U, rd+.Origin: R. A. Fisher, about 1937. 50% Gruneberg's CBA, 28.5% Fisher's colour stocks and 21.5% Gruneberg's wavy stock, the latter two being unrelated stocks of American origin. To Medawar 1947, to Silvers at F23 in 1957, to Jackson Laboratory 1967.
Characteristics: Females do not reject male isografts. Unusual induction of kidney beta-glucuronidase by testosterone (
Staats, 1976). High plasma cholinesterase activity (1/22) (
Angel et al., 1967., 1967). Resistant to skin ulceration by DMBA (cf. 9/22) (
Thomas et al., 1973., 1973). High degree of genetic distinctiveness (2/27) (
Taylor, 1972). Carries no detectable endogenous ecotropic MuLV DNA sequences (
Jenkins et al 1982). F1 hybrid crosses with CBA have been suggested as a good model for auditory research (
Henry and McGinn 1992). Resistant to the induction of arthritis by type II collagen (
Ortman et al, 1994).
Angel C. R., Mahin D. T., Farris R. D., and Woodward K. T. (1967) Heritability of plasma cholinesterase activity in inbred mouse strains. Science 156, 529-530.Taylor B. A. (1972) Genetic relationship between inbred strains of mice. J. Hered. 63, 83-86.
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