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MGI - Inbred Strains: IVCS

Inbred Strains of Mice: IVCS

IVCS

Inbr: F73 (Csk). Albino. Genet:

a, B, c, S.

Origin: From outbred ddN mice of Cen. Lab. Exp. Anim., Japan, by selective breeding for regular 4 day oestrus cycles, 1960.

Characteristics

Litter size averages about 9-10 with 70 day body weight about 24 g in females and 30 g in males. Mice are docile (

Nobunga, 1973

). Resistant to induction of anaphylactic shock by ovalbumin (cf. 6/13) (

Tanioka and Esaki, 1971

).

Nobunga T. (1973) Establishment by selective inbreeding of the IVCS strain and related sister strains of the mouse, demonstrating regularly repeated 4-day estrus cycles. Lab. Animal Sci. 23, 803-811.

Tanioka Y. and Esaki K. (1971) Strain differences in mortality of anaphylactic shock in mice-challenging by intravenous injection. Exp. Animals (Japan) 20, 127-130.

INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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