Inbred Strains of Mice: GRS
GRSInbr (A) 101. Albino
a,c.Origin:Formerly called GR/A. Muhlbock 1965 from outbred mice obtained from Grumbach in Zurich.
CharacteristicsBreeding females have a high incidence of mammary tumours which are highly hormone-responsive. Carries a mammary tumour agent different from MTI, transmitted by milk and gametes, which is not eliminated by foster nursing. Hormone-dependent tumours are also produced in GRS x RIII F
1hybrids (Muhlbock, 1965
; van Nie and Thung, 1965; Brcand and Daehnfeldt, 1973). High incidence of hepatomas in mice treated with normal horse serum or horse-anti-mouse antilymphocyte serum (
Den Engelese et al., 1976., 1976). Leukosis 11% (
Hilgers and Galesloot, 1973). Susceptibility to mammary tumour induction with progesterone and oestrone in ovariectomised mice may be due to a single gene, although linkage with eighteen marker loci could not be established (
van Nie and Hilgers, 1976). Resistant to the development of uterine tumours following treatment with DMBA at 4-weeks of age (cf 3/6) (
Tsubura et al, 1993).
Brcand P. and Daehnfeldt J. L. (1973) Enzyme patterns of glucose catabolism in hormone-dependent and independent mammary tumours of GR mice. Eur. J. Cancer 9, 763-770. INBRED STRAINS OF MICERetroSearch is an open source project built by @garambo | Open a GitHub Issue
Search and Browse the WWW like it's 1997 | Search results from DuckDuckGo
HTML:
3.2
| Encoding:
UTF-8
| Version:
0.7.4