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Showing content from http://www.bioconductor.org/packages/devel/bioc/html/../../bioc/html/../../bioc/html/cypress.html below:

Bioconductor - cypress (development version)

cypress

This is the development version of cypress; for the stable release version, see cypress.

Cell-Type-Specific Power Assessment

Bioconductor version: Development (3.22)

CYPRESS is a cell-type-specific power tool. This package aims to perform power analysis for the cell-type-specific data. It calculates FDR, FDC, and power, under various study design parameters, including but not limited to sample size, and effect size. It takes the input of a SummarizeExperimental(SE) object with observed mixture data (feature by sample matrix), and the cell-type mixture proportions (sample by cell-type matrix). It can solve the cell-type mixture proportions from the reference free panel from TOAST and conduct tests to identify cell-type-specific differential expression (csDE) genes.

Author: Shilin Yu [aut, cre] ORCID: 0000-0002-5494-1960 , Guanqun Meng [aut], Wen Tang [aut]

Maintainer: Shilin Yu <sy597 at georgetown.edu>

Citation (from within R, enter citation("cypress")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("cypress")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("cypress")
Details biocViews DataImport, GeneExpression, RNASeq, Sequencing, Software Version 1.5.0 In Bioconductor since BioC 3.19 (R-4.4) (1 year) License GPL-2 | GPL-3 Depends R (>= 4.4.0) Imports stats, abind, sirt, MASS, TOAST, tibble, parallel, preprocessCore, SummarizedExperiment, TCA, PROPER, methods, dplyr, utils, RColorBrewer, graphics, edgeR, BiocParallel, checkmate, mvtnorm, DESeq2, rlang, e1071 System Requirements URL https://github.com/renlyly/cypress Bug Reports https://github.com/renlyly/cypress/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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