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Showing content from http://www.bioconductor.org/packages/devel/bioc/html/../../bioc/html/../../bioc/html/HiCDOC.html below:

Bioconductor - HiCDOC (development version)

HiCDOC

This is the development version of HiCDOC; for the stable release version, see HiCDOC.

A/B compartment detection and differential analysis

Bioconductor version: Development (3.22)

HiCDOC normalizes intrachromosomal Hi-C matrices, uses unsupervised learning to predict A/B compartments from multiple replicates, and detects significant compartment changes between experiment conditions. It provides a collection of functions assembled into a pipeline to filter and normalize the data, predict the compartments and visualize the results. It accepts several type of data: tabular `.tsv` files, Cooler `.cool` or `.mcool` files, Juicer `.hic` files or HiC-Pro `.matrix` and `.bed` files.

Author: Kurylo Cyril [aut], Zytnicki Matthias [aut], Foissac Sylvain [aut], Maigné Élise [aut, cre]

Maintainer: Maigné Élise <elise.maigne at inrae.fr>

Citation (from within R, enter citation("HiCDOC")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("HiCDOC")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HiCDOC")
Details biocViews Clustering, DNA3DStructure, HiC, Normalization, Sequencing, Software Version 1.11.1 In Bioconductor since BioC 3.16 (R-4.2) (2.5 years) License LGPL-3 Depends InteractionSet, GenomicRanges, SummarizedExperiment, R (>= 4.1.0) Imports methods, ggplot2, Rcpp (>= 0.12.8), stats, S4Vectors, gtools, pbapply, BiocParallel, BiocGenerics, grid, cowplot, gridExtra, data.table, multiHiCcompare, GenomeInfoDb System Requirements C++11 URL https://github.com/mzytnicki/HiCDOC Bug Reports https://github.com/mzytnicki/HiCDOC/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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