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Showing content from http://www.bioconductor.org/packages/devel/bioc/html/../../bioc/html/../../bioc/html/CIMICE.html below:

Bioconductor - CIMICE (development version)

CIMICE

This is the development version of CIMICE; for the stable release version, see CIMICE.

CIMICE-R: (Markov) Chain Method to Inferr Cancer Evolution

Bioconductor version: Development (3.22)

CIMICE is a tool in the field of tumor phylogenetics and its goal is to build a Markov Chain (called Cancer Progression Markov Chain, CPMC) in order to model tumor subtypes evolution. The input of CIMICE is a Mutational Matrix, so a boolean matrix representing altered genes in a collection of samples. These samples are assumed to be obtained with single-cell DNA analysis techniques and the tool is specifically written to use the peculiarities of this data for the CMPC construction.

Author: Nicolò Rossi [aut, cre] (Lab. of Computational Biology and Bioinformatics, Department of Mathematics, Computer Science and Physics, University of Udine, ORCID: ORCID: 0000-0002-6353-7396 )

Maintainer: Nicolò Rossi <olocin.issor at gmail.com>

Citation (from within R, enter citation("CIMICE")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("CIMICE")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("CIMICE")
Details biocViews BiologicalQuestion, GraphAndNetwork, NetworkInference, Phylogenetics, ResearchField, SingleCell, Software, StatisticalMethod, Technology Version 1.17.0 In Bioconductor since BioC 3.13 (R-4.1) (4 years) License Artistic-2.0 Depends Imports dplyr, ggplot2, glue, tidyr, igraph, networkD3, visNetwork, ggcorrplot, purrr, ggraph, stats, utils, maftools, assertthat, tidygraph, expm, Matrix System Requirements URL https://github.com/redsnic/CIMICE Bug Reports https://github.com/redsnic/CIMICE/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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