First Launch: 2016-07-07. Last Launch: 2017-04-20. Number: 4 .

The improvements were as follow:

• Solar cell efficiency increased from 12% to 14% (from 12%) solar panel area increased by 1.1 m2
• A fifth 155 Ampere-hour battery added
• Additional micro meteoroid protection blankets on the orbital module at the request of NASA
• Introduction of the TsVM-101 computer, with a mass of 8.3 kg vs. the 70 kg of the Argon-16 it replaced
• Rearranged attitude control thrusters, allowing docking and undocking with one failed thruster or de-orbit with two failed thrusters.
• Improved redundancy using dual independent propellant supply subsystems.
• Addition of a Satellite Navigation System (ASN-K) using GLONASS and GPS signals for autonomous navigation. It is linked to a COSPAS-SARSAT transponder to transmit the location of the capsule within 10 m at the time of parachute deployment and landing.
• Integrated communications and telemetry system, EKTS, that can use Luch, TDRS, or EDRS satellites for relay to ground stations
• Kurs-NA automatic docking system using all-Russian components and a single phased array antenna replacing three earliers antennae
• Backup electric drive in the docking system
• Digital television
• LED powered external illumination system
• A new flght data recorder recording voice and data during the mission.

Crew Size: 3. Orbital Storage: 200 days. Habitable Volume: 9.00 m3. Spacecraft delta v: 390 m/s (1,270 ft/sec). Electric System: 0.70 average kW.

• Soyuz MS-01 - . Call Sign: Irkut. Crew: Ivanishin, Onishi, Rubins. Backup Crew: Novitskiy, Pesquet, Whitson. Return Crew: Ivanishin, Onishi, Rubins. Nation: Russia. Program: ISS. Class: Manned. Type: Manned spacecraft. Flight: Soyuz MS-01. Spacecraft Bus: Soyuz. Spacecraft: Soyuz MS. Duration: 115.10 days. Decay Date: 2016-10-30 03:58:00 . USAF Sat Cat: 41639 . COSPAR: 2016-044A. Apogee: 239 km (148 mi). Perigee: 181 km (112 mi). Inclination: 51.70 deg.

  Launched on into a 181 x 239 km orbit; docked with the ISS Rassvet module at 0406 UTC Jul 9. The Soyuz MS was a new variant of the ferry ship with upgraded onboard systems. Crew was Anatoliy Ivanishin (Roscosmos), Takuya Onishi (JAXA) and Kate Rubins (NASA). On Oct 30 at 0035 UTC Ivanishin, Onishi and Rubins undocked from Rassvet in Soyuz MS-01; they landed in Kazakhstan at 0358 UTC.

• Soyuz MS-02 - . Call Sign: Favor. Crew: Ryzhikov, Borisenko, Kimbrough. Backup Crew: Misurkin, Tikhonov, Vande Hei. Return Crew: Ryzhikov, Borisenko, Kimbrough. Nation: Russia. Program: ISS. Class: Manned. Type: Manned spacecraft. Flight: Soyuz MS-02. Spacecraft Bus: Soyuz. Spacecraft: Soyuz MS. Duration: 173.14 days. Decay Date: 2017-04-10 11:20:00 . USAF Sat Cat: 41820 . COSPAR: 2016-063A. Apogee: 306 km (190 mi). Perigee: 289 km (179 mi). Inclination: 51.60 deg.

  Soyuz MS-02 with astronauts Sergey Ryzhikov, Andrey Borisenko and Shane Kimbrough. They docked with the Poisk module at 0952 UTC Oct 21. On Apr 10, Soyuz MS-02 undocked from Poisk at 0757 UTC and landed in Kazakhstan at 1120 UTC, returing Ryzhikov, Borisenko and Kimbrough to Earth. Peggy Whitson became ISS commander of Expedition 51.

• Soyuz MS-03 - . Call Sign: Kazbek. Crew: Novitskiy, Pesquet, Whitson. Backup Crew: Yurchikhin, Fischer, Nespoli. Return Crew: Novitskiy, Pesquet. Nation: Russia. Program: ISS. Class: Manned. Type: Manned spacecraft. Flight: Soyuz MS-03. Spacecraft Bus: Soyuz. Spacecraft: Soyuz MS. Decay Date: 2017-06-02 . USAF Sat Cat: 41864 . COSPAR: 2016-070A. Apogee: 228 km (141 mi). Perigee: 195 km (121 mi). Inclination: 51.60 deg. Soyuz MS-03 was launched with the crew of Oleg Novitskiy (Roskosmos), Thomas Pesquet (ESA) and Peggy Whitson (NASA). The Soyuz docked with the ISS Rassvet module at 2158 UTC Nov 19..

• Soyuz MS-04 - . Call Sign: Olympus. Crew: Yurchikhin, Fischer. Backup Crew: Ryazansky, Bresnik. Return Crew: Yurchikhin, Fischer, Whitson. Nation: Russia. Program: ISS. Class: Manned. Type: Manned spacecraft. Flight: Soyuz MS-04. Spacecraft Bus: Soyuz. Spacecraft: Soyuz MS. Decay Date: 2017-09-03 . USAF Sat Cat: 42682 . COSPAR: 2017-020A. Apogee: 409 km (254 mi). Perigee: 399 km (247 mi). Inclination: 51.60 deg. Period: 92.66 min.

  See Soyuz-MS 04. Soyuz MS-04 docked with the ISS Poisk module 6hr 4min after launch. Soyuz commander was Fyodor Yurchikin and flight engineer was Jack Fischer. This was the first two-person Soyuz mission in 14 years (Soyuz TMA-2 in Apr 2003), as Russia scaled back its ISS crew pending completion of the delayed Nauka module.

• Soyuz MS-05 - . Call Sign: Borei. Crew: Ryazansky, Bresnik, Nespoli. Backup Crew: Misurkin, Vande Hai, Kanai. Return Crew: Ryazansky, Bresnik, Nespoli. Payload: Soyuz 11F732A48 No. 736. Nation: Russia. Program: ISS. Class: Manned. Type: Manned spacecraft. Flight: Soyuz MS-05. Spacecraft Bus: Soyuz. Spacecraft: Soyuz MS. USAF Sat Cat: 42898 . COSPAR: 2017-043A. Apogee: 407 km (252 mi). Perigee: 403 km (250 mi). Inclination: 51.64 deg. Period: 92.66 min. See Soyuz-MS 05. ..

• Soyuz MS-06 - . Call Sign: Altair. Crew: Misurkin, Vande Hai, Acaba. Backup Crew: Shkaplerov, Tingle, Walker, Shannon. Return Crew: Misurkin, Vande Hai, Acaba. Payload: Soyuz 11F732A48 No. 734. Nation: Russia. Program: ISS. Class: Manned. Type: Manned spacecraft. Flight: Soyuz MS-06. Spacecraft Bus: Soyuz. Spacecraft: Soyuz MS. USAF Sat Cat: 42937 . COSPAR: 2017-054A. Apogee: 407 km (252 mi). Perigee: 402 km (249 mi). Inclination: 51.64 deg. Period: 92.65 min. See Soyuz-MS 06. ..

• Soyuz MS-07 - . Call Sign: Astraeus. Crew: Shkaplerov, Tingle, Kanai. Backup Crew: Prokopyev, Gerst, Epps. Return Crew: Shkaplerov, Tingle, Kanai. Payload: Soyuz 11F732A48 No. 737. Nation: Russia. Program: ISS. Class: Manned. Type: Manned spacecraft. Flight: Soyuz MS-07. Spacecraft Bus: Soyuz. Spacecraft: Soyuz MS. USAF Sat Cat: 43063 . COSPAR: 2017-081A. Apogee: 407 km (252 mi). Perigee: 402 km (249 mi). Inclination: 51.64 deg. Period: 92.66 min. See Soyuz-MS 07. ..

• Soyuz MS-08 - . Call Sign: Hawaii. Crew: Artemyev, Feustel, Arnold. Backup Crew: Ovchinin, Hague. Return Crew: Artemyev, Feustel, Arnold. Payload: Soyuz 11F732A48 No. 738. Nation: Russia. Program: ISS. Class: Manned. Type: Manned spacecraft. Flight: Soyuz MS-08. Spacecraft Bus: Soyuz. Spacecraft: Soyuz MS. USAF Sat Cat: 43238 . COSPAR: 2018-026A. Apogee: 408 km (253 mi). Perigee: 403 km (250 mi). Inclination: 51.64 deg. Period: 92.68 min. See Soyuz-MS 08. ..

• Soyuz MS-09 - . Call Sign: Altai. Crew: Prokopyev, Gerst, Aunon. Backup Crew: Kononenko, Saint-Jacques, McClain. Return Crew: Prokopyev, Gerst, Aunon. Payload: Soyuz 11F732A48 No. 739. Nation: Russia. Program: ISS. Class: Manned. Type: Manned spacecraft. Flight: Soyuz MS-09. Spacecraft Bus: Soyuz. Spacecraft: Soyuz MS. USAF Sat Cat: 43493 . COSPAR: 2018-051A. Apogee: 408 km (253 mi). Perigee: 401 km (249 mi). Inclination: 51.64 deg. Period: 92.66 min. See Soyuz-MS 09. ..

• Soyuz MS-10 - . Call Sign: Burlak. Crew: Kononenko, Saint-Jacques, McClain. Backup Crew: Skvortsov, Parmitano, Morgan, Andrew. Nation: Russia. Program: ISS. Class: Manned. Type: Manned spacecraft. Flight: Soyuz MS-10. Spacecraft Bus: Soyuz. Spacecraft: Soyuz MS. COSPAR: 2018-F01. See Soyuz-MS 10. ..

• Soyuz MS-11 - . Call Sign: Antares. Crew: Ovchinin, Hague. Backup Crew: Kononenko, Saint-Jacques. Return Crew: Ovchinin, Hague. Nation: Russia. Program: ISS. Class: Manned. Type: Manned spacecraft. Flight: Soyuz MS-11. Spacecraft Bus: Soyuz. Spacecraft: Soyuz MS. USAF Sat Cat: 43756 . COSPAR: 2018-098A. Apogee: 411 km (255 mi). Perigee: 404 km (251 mi). Inclination: 51.64 deg. Period: 92.71 min. See Soyuz-MS 11. ..