Provides tools for analyzing spatial cell-cell interactions based on ligand-receptor pairs, including functions for local, regional, and global analysis using spatial transcriptomics data. Integrates with databases like 'CellChat' <http://www.cellchat.org/>, 'CellPhoneDB' <https://www.cellphonedb.org/>, 'Cellinker' <https://www.rna-society.org/cellinker/index.html>, 'ICELLNET' <https://github.com/soumelis-lab/ICELLNET>, and 'ConnectomeDB' <https://humanconnectome.org/software/connectomedb/> to identify ligand-receptor pairs, visualize interactions through heatmaps, chord diagrams, and infer interactions on different spatial scales.
Version: 1.0.4 Depends: R (≥ 3.5.0) Imports: Rcpp (≥ 1.0.13), Seurat (≥ 4.0.0), nnls, ggrepel, pheatmap, circlize (≥ 0.4.12), Matrix, dplyr, patchwork, grDevices, reshape2, graphics, ggplot2, FNN LinkingTo: Rcpp, RcppArmadillo Published: 2025-05-12 DOI: 10.32614/CRAN.package.SpaCCI Author: Li-Ting Ku [aut, cre] Maintainer: Li-Ting Ku <lku at mdanderson.org> License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] NeedsCompilation: yes CRAN checks: SpaCCI results Documentation: Downloads: Linking:Please use the canonical form https://CRAN.R-project.org/package=SpaCCI to link to this page.
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