When multiple Cox proportional hazard models are performed on clinical data (month or year and status) and a set of differential expressions of genes, the results (Hazard risks, z-scores and p-values) can be used to create gene-expression signatures. Weights are calculated using the survival p-values of genes and are utilized to calculate expression values of the signature across the selected genes in all patients in a cohort. A Single or multiple univariate or multivariate Cox proportional hazard survival analyses of the patients in one cohort can be performed by using the gene-expression signature and visualized using our survival plots.
Version: 1.0.0 Depends: R (≥ 3.5.0) Imports: stats, utils, graphics, grDevices, dplyr, forestplot, gplots, gtools, survival, survminer, ggplot2 Suggests: Rmisc Published: 2023-07-19 DOI: 10.32614/CRAN.package.signatureSurvival Author: Yuan-De Tan [aut, cre], Yuguang Ban [ctb] Maintainer: Yuan-De Tan <tanyuande at gmail.com> License: GPL (≥ 3) NeedsCompilation: no CRAN checks: signatureSurvival results [issues need fixing before 2025-09-03] Documentation: Downloads: Linking:Please use the canonical form https://CRAN.R-project.org/package=signatureSurvival to link to this page.
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