Simple and transparent parsing of genotype/dosage data from an input Variant Call Format (VCF) file, matching of genotype coordinates to the component Single Nucleotide Polymorphisms (SNPs) of an existing polygenic score (PGS), and application of SNP weights to dosages for the calculation of a polygenic score for each individual in accordance with the additive weighted sum of dosages model. Methods are designed in reference to best practices described by Collister, Liu, and Clifton (2022) <doi:10.3389/fgene.2022.818574>.
Version: 3.0.1 Depends: R (≥ 4.2.0) Imports: vcfR, pROC, data.table, reshape2, BoutrosLab.plotting.general, lattice Suggests: knitr, rmarkdown, testthat (≥ 3.0.0) Published: 2025-03-05 DOI: 10.32614/CRAN.package.ApplyPolygenicScore Author: Paul Boutros [cre], Nicole Zeltser [aut], Rachel Dang [ctb] Maintainer: Paul Boutros <PBoutros at mednet.ucla.edu> License: GPL-2 NeedsCompilation: no Materials: README, NEWS CRAN checks: ApplyPolygenicScore results Documentation: Downloads: Linking:Please use the canonical form https://CRAN.R-project.org/package=ApplyPolygenicScore to link to this page.
RetroSearch is an open source project built by @garambo | Open a GitHub Issue
Search and Browse the WWW like it's 1997 | Search results from DuckDuckGo
HTML:
3.2
| Encoding:
UTF-8
| Version:
0.7.4