Allows to estimate and test high-dimensional mediation effects based on advanced mediator screening and penalized regression techniques. Methods used in the package refer to Zhang H, Zheng Y, Zhang Z, Gao T, Joyce B, Yoon G, Zhang W, Schwartz J, Just A, Colicino E, Vokonas P, Zhao L, Lv J, Baccarelli A, Hou L, Liu L. Estimating and Testing High-dimensional Mediation Effects in Epigenetic Studies. Bioinformatics. (2016) <doi:10.1093/bioinformatics/btw351>. PMID: 27357171.
Version: 2.3.2 Depends: R (≥ 3.4.0), ncvreg, glmnet Imports: utils, stats, MASS, survival, HDMT, hdi, conquer, quantreg, hommel, iterators, parallel, foreach, doParallel Suggests: knitr, rmarkdown, testthat Published: 2025-06-11 DOI: 10.32614/CRAN.package.HIMA Author: Yinan Zheng [aut, cre], Haixiang Zhang [aut], Lifang Hou [aut], Lei Liu [aut, cph] Maintainer: Yinan Zheng <y-zheng at northwestern.edu> BugReports: https://github.com/YinanZheng/HIMA/issues/ License: GPL-3 URL: https://github.com/YinanZheng/HIMA/ NeedsCompilation: no Citation: HIMA citation info Materials: README NEWS In views: Epidemiology CRAN checks: HIMA results Documentation: Downloads: Linking:Please use the canonical form https://CRAN.R-project.org/package=HIMA to link to this page.
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