Provides functions for the joint analysis of Q sets of p-values obtained for the same list of items. This joint analysis is performed by querying a composite hypothesis, i.e. an arbitrary complex combination of simple hypotheses, as described in Mary-Huard et al. (2021) <doi:10.1093/bioinformatics/btab592> and De Walsche et al.(2023) <doi:10.1101/2024.03.17.585412>. In this approach, the Q-uplet of p-values associated with each item is distributed as a multivariate mixture, where each of the 2^Q components corresponds to a specific combination of simple hypotheses. The dependence between the p-value series is considered using a Gaussian copula function. A p-value for the composite hypothesis test is derived from the posterior probabilities.
Version: 2.1.0 Depends: R (≥ 2.10) Imports: copula, dplyr, graphics, ks, purrr, qvalue, Rcpp, stats, stringr, utils LinkingTo: Rcpp, RcppArmadillo Published: 2025-07-04 DOI: 10.32614/CRAN.package.qch Author: Tristan Mary-Huard [aut, cre], Annaig De Walsche [aut], Franck Gauthier [ctb] Maintainer: Tristan Mary-Huard <tristan.mary-huard at agroparistech.fr> License: GPL-3 NeedsCompilation: yes CRAN checks: qch results Documentation: Downloads: Linking:Please use the canonical form https://CRAN.R-project.org/package=qch to link to this page.
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