Contains functions carrying out adaptive procedures using mixed scaling approach to establish bioequivalence for in-vitro permeation test (IVPT) data. Currently, the package provides procedures based on parallel replicate design and balanced data, according to the U.S. Food and Drug Administration's "Draft Guidance on Acyclovir" <https://www.accessdata.fda.gov/drugsatfda_docs/psg/Acyclovir_topical%20cream_RLD%2021478_RV12-16.pdf>. Potvin et al. (2008) <doi:10.1002/pst.294> provides the basis for our adaptive design (see Method B). For a comprehensive overview of the method, refer to Lim et al. (2023) <doi:10.1002/pst.2333>. This package reflects the views of the authors and should not be construed to represent the views or policies of the U.S. Food and Drug Administration.
Version: 1.1.0 Depends: R (≥ 3.4) Imports: Rcpp, rgl LinkingTo: Rcpp, RcppArmadillo, RcppProgress Suggests: knitr, rmarkdown Published: 2024-01-26 DOI: 10.32614/CRAN.package.adaptIVPT Author: Daeyoung Lim [aut, cre], Elena Rantou [ctb], Jessica Kim [ctb], Sungwoo Choi [ctb], Nam Hee Choi [ctb], Stella Grosser [ctb] Maintainer: Daeyoung Lim <Daeyoung.Lim at fda.hhs.gov> License: GPL (≥ 3) NeedsCompilation: yes Citation: adaptIVPT citation info Materials: NEWS CRAN checks: adaptIVPT results Documentation: Downloads: Linking:Please use the canonical form https://CRAN.R-project.org/package=adaptIVPT to link to this page.
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