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CRAN: Package twosigma

twosigma: DE Analysis for Single-Cell RNA-Sequencing Data

Implements the TWO-Component Single Cell Model-Based Association Method (TWO-SIGMA) for gene-level differential expression (DE) analysis and DE-based gene set testing of single-cell RNA-sequencing datasets. See Van Buren et al. (2020) <doi:10.1002/gepi.22361> and Van Buren et al. (2021) <doi:10.1101/2021.01.24.427979>.

Version: 1.0.2 Imports: multcomp (≥ 1.4-13), glmmTMB, methods, pscl (≥ 1.5.5), pbapply (≥ 1.4.0), parallel (≥ 3.6.3), doParallel (≥ 1.0.15) Suggests: testthat Published: 2021-12-13 DOI: 10.32614/CRAN.package.twosigma Author: Eric Van Buren [aut, cre], Yun Li [aut], Di Wu [aut], Ming Hu [aut] Maintainer: Eric Van Buren <edvanburen at gmail.com> BugReports: https://github.com/edvanburen/twosigma/issues License: AGPL-3 URL: https://github.com/edvanburen/twosigma NeedsCompilation: no Materials: README NEWS CRAN checks: twosigma results Documentation: Downloads: Linking:

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