A minimal set of routines to calculate the Grantham distance <doi:10.1126/science.185.4154.862>. The Grantham distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.
Version: 0.1.4 Depends: R (≥ 4.1.0) Imports: tibble, dplyr Suggests: spelling, testthat (≥ 3.0.0) Published: 2025-05-31 DOI: 10.32614/CRAN.package.grantham Author: Ramiro Magno [aut, cre], Isabel Duarte [aut], Ana-Teresa Maia [aut], University of Algarve [fnd], CINTESIS [fnd], Pattern Institute [cph, fnd] Maintainer: Ramiro Magno <rmagno at pattern.institute> BugReports: https://github.com/patterninstitute/grantham/issues License: MIT + file LICENSE URL: https://www.pattern.institute/grantham/, https://github.com/patterninstitute/grantham NeedsCompilation: no Language: en-US Materials: README, NEWS CRAN checks: grantham results Documentation: Downloads: Reverse dependencies: Linking:Please use the canonical form https://CRAN.R-project.org/package=grantham to link to this page.
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