Tipping point analysis for clinical trials that employ Bayesian dynamic borrowing via robust meta-analytic predictive (MAP) priors. Further functions facilitate expert elicitation of a primary weight of the informative component of the robust MAP prior and computation of operating characteristics. Intended use is the planning, analysis and interpretation of extrapolation studies in pediatric drug development, but applicability is generally wider.
Version: 0.5.2 Depends: R (≥ 3.5.0) Imports: dplyr, magrittr, purrr, ggplot2, RBesT, assertthat, stats, furrr, future Suggests: knitr, rmarkdown, tidyr, tibble, testthat (≥ 3.0.0) Published: 2023-08-14 DOI: 10.32614/CRAN.package.tipmap Author: Christian Stock [aut, cre], Morten Dreher [aut], Emma Torrini [ctb], Boehringer Ingelheim Pharma GmbH & Co. KG [cph, fnd] Maintainer: Christian Stock <christian.stock at boehringer-ingelheim.com> BugReports: https://github.com/Boehringer-Ingelheim/tipmap/issues License: Apache License 2.0 URL: https://github.com/Boehringer-Ingelheim/tipmap NeedsCompilation: no Materials: README NEWS CRAN checks: tipmap results Documentation: Downloads: Linking:Please use the canonical form https://CRAN.R-project.org/package=tipmap to link to this page.
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