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CRAN: Package invivoPKfit

invivoPKfit: Fits Toxicokinetic Models to In Vivo PK Data Sets

Takes in vivo toxicokinetic concentration-time data and fits parameters of 1-compartment and 2-compartment models for each chemical. These methods are described in detail in "Informatics for Toxicokinetics" (submitted).

Version: 2.0.1 Depends: R (≥ 4.1.0) Imports: cli, devtools, dplyr, ggplot2, glue, httk, magrittr, MASS, Matrix, multidplyr (≥ 0.1.3), numDeriv, optimx, PK, pracma, purrr, rlang, scales, tibble, tidyr, tidyselect Suggests: cowplot, knitr, RColorBrewer, rmarkdown, stringr, testthat (≥ 3.0.0), tidyverse Published: 2025-03-24 DOI: 10.32614/CRAN.package.invivoPKfit Author: John Wambaugh [aut, cre], Caroline Ring [aut], Gilberto Padilla Mercado [aut], Chris Cook [aut] Maintainer: John Wambaugh <wambaugh.john at epa.gov> License: GPL-3 NeedsCompilation: no Materials: README, NEWS CRAN checks: invivoPKfit results Documentation: Downloads: Linking:

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