The R package 'ashr' implements an Empirical Bayes approach for large-scale hypothesis testing and false discovery rate (FDR) estimation based on the methods proposed in M. Stephens, 2016, "False discovery rates: a new deal", <doi:10.1093/biostatistics/kxw041>. These methods can be applied whenever two sets of summary statistics—estimated effects and standard errors—are available, just as 'qvalue' can be applied to previously computed p-values. Two main interfaces are provided: ash(), which is more user-friendly; and ash.workhorse(), which has more options and is geared toward advanced users. The ash() and ash.workhorse() also provides a flexible modeling interface that can accommodate a variety of likelihoods (e.g., normal, Poisson) and mixture priors (e.g., uniform, normal).
Version: 2.2-63 Depends: R (≥ 3.1.0) Imports: Matrix, stats, graphics, Rcpp (≥ 0.10.5), truncnorm, mixsqp, SQUAREM, etrunct, invgamma LinkingTo: Rcpp Suggests: testthat, knitr, rmarkdown, ggplot2, REBayes Published: 2023-08-21 DOI: 10.32614/CRAN.package.ashr Author: Matthew Stephens [aut], Peter Carbonetto [aut, cre], Chaoxing Dai [ctb], David Gerard [aut], Mengyin Lu [aut], Lei Sun [aut], Jason Willwerscheid [aut], Nan Xiao [aut], Mazon Zeng [ctb] Maintainer: Peter Carbonetto <pcarbo at uchicago.edu> BugReports: https://github.com/stephens999/ashr/issues License: GPL (≥ 3) URL: https://github.com/stephens999/ashr NeedsCompilation: yes Materials: NEWS In views: Bayesian CRAN checks: ashr results Documentation: Downloads: Reverse dependencies: Reverse depends: mashr Reverse imports: cytoKernel, debrowser, DiffBind, dreamlet, ebnm, fastTopics, ldsep, limorhyde2, MixTwice, QTLExperiment Reverse suggests: BindingSiteFinder, colocboost, dar, DESeq2, flashier, ncvreg, palasso, ribosomeProfilingQC, topconfects Linking:Please use the canonical form https://CRAN.R-project.org/package=ashr to link to this page.
RetroSearch is an open source project built by @garambo | Open a GitHub Issue
Search and Browse the WWW like it's 1997 | Search results from DuckDuckGo
HTML:
3.2
| Encoding:
UTF-8
| Version:
0.7.4