It provides functions to design historical controlled trials with survival outcome by group sequential method. The options for interim look boundaries are efficacy only, efficacy & futility or futility only. It also provides the function to monitor the trial for any unplanned look. The package is based on Jianrong Wu, Xiaoping Xiong (2016) <doi:10.1002/pst.1756> and Jianrong Wu, Yimei Li (2020) <doi:10.1080/10543406.2019.1684305>.
Version: 0.7.2 Imports: Rdpack, diversitree, mvtnorm, flexsurv, stats, survival, crayon Published: 2022-11-17 DOI: 10.32614/CRAN.package.HCTDesign Author: Tushar Patni [aut, cre], Yimei Li [aut], Jianrong Wu [aut], Arzu Onar-Thomas [aut] Maintainer: Tushar Patni <patni006 at umn.edu> License: GPL-3 NeedsCompilation: no CRAN checks: HCTDesign results Documentation: Downloads: Linking:Please use the canonical form https://CRAN.R-project.org/package=HCTDesign to link to this page.
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