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CRAN: Package clinDR

clinDR: Simulation and Analysis Tools for Clinical Dose Response Modeling

Bayesian and ML Emax model fitting, graphics and simulation for clinical dose response. The summary data from the dose response meta-analyses in Thomas, Sweeney, and Somayaji (2014) <doi:10.1080/19466315.2014.924876> and Thomas and Roy (2016) <doi:10.1080/19466315.2016.1256229> Wu, Banerjee, Jin, Menon, Martin, and Heatherington(2017) <doi:10.1177/0962280216684528> are included in the package. The prior distributions for the Bayesian analyses default to the posterior predictive distributions derived from these references.

Version: 2.4.1 Depends: R (≥ 3.5.0), rstan (≥ 2.17.3), shiny Imports: foreach, graphics, DoseFinding, stats, mvtnorm, utils, parallel, doParallel, ggplot2, tidyr, purrr, tibble, dplyr, glue, waiter Published: 2023-08-09 DOI: 10.32614/CRAN.package.clinDR Author: Neal Thomas [aut, cre], Jing Wu [aut], Mike K. Smith [aut] Maintainer: Neal Thomas <snthomas99 at gmail.com> License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] NeedsCompilation: no Materials: NEWS In views: Pharmacokinetics CRAN checks: clinDR results [issues need fixing before 2025-09-03] Documentation: Downloads: Reverse dependencies: Linking:

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