Implements target trial emulation methods to apply randomized clinical trial design and analysis in an observational setting. Using marginal structural models, it can estimate intention-to-treat and per-protocol effects in emulated trials using electronic health records. A description and application of the method can be found in Danaei et al (2013) <doi:10.1177/0962280211403603>.
Version: 0.0.4.5 Depends: R (≥ 4.1.0) Imports: broom (≥ 0.7.10), checkmate, data.table (≥ 1.9.8), DBI, duckdb, formula.tools, lifecycle, lmtest, methods, mvtnorm, parglm, Rcpp, sandwich LinkingTo: Rcpp Suggests: knitr, parsnip, rmarkdown, rpart, testthat (≥ 3.0.0), withr Published: 2025-06-13 DOI: 10.32614/CRAN.package.TrialEmulation Author: Isaac Gravestock [aut, cre], Li Su [aut], Roonak Rezvani [aut] (Original package author), Julia Moesch [aut], Medical Research Council (MRC) [fnd], F. Hoffmann-La Roche AG [cph, fnd] Maintainer: Isaac Gravestock <isaac.gravestock at roche.com> BugReports: https://github.com/Causal-LDA/TrialEmulation/issues License: Apache License (≥ 2) URL: https://causal-lda.github.io/TrialEmulation/, https://github.com/Causal-LDA/TrialEmulation NeedsCompilation: yes Language: en-GB Materials: README NEWS CRAN checks: TrialEmulation results Documentation: Downloads: Linking:Please use the canonical form https://CRAN.R-project.org/package=TrialEmulation to link to this page.
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