This is the development version of MesKit; for the stable release version, see MesKit.
A tool kit for dissecting cancer evolution from multi-region derived tumor biopsies via somatic alterationsBioconductor version: Development (3.22)
MesKit provides commonly used analysis and visualization modules based on mutational data generated by multi-region sequencing (MRS). This package allows to depict mutational profiles, measure heterogeneity within or between tumors from the same patient, track evolutionary dynamics, as well as characterize mutational patterns on different levels. Shiny application was also developed for a need of GUI-based analysis. As a handy tool, MesKit can facilitate the interpretation of tumor heterogeneity and the understanding of evolutionary relationship between regions in MRS study.
Author: Mengni Liu [aut, cre] ORCID: 0000-0001-9938-9973 , Jianyu Chen [aut, ctb] ORCID: 0000-0003-4491-9265 , Xin Wang [aut, ctb] ORCID: 0000-0002-6072-599X
Maintainer: Mengni Liu <niinleslie at gmail.com>
Citation (from within R, entercitation("MesKit")): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("MesKit")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("MesKit")Follow Installation instructions to use this package in your R session.
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